Zobrazeno 1 - 10
of 170
pro vyhledávání: '"John F. Malone"'
Autor:
Brian Daly, Thomas S. Moody, Allen J. M. Huxley, Chaoyi Yao, Benjamin Schazmann, Andre Alves-Areias, John F. Malone, H. Q. Nimal Gunaratne, Peter Nockemann, A. Prasanna de Silva
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-7 (2019)
While many processes in biological cells can be understood in terms of molecular logic gates that process information sequentially and combinationally, the design and construction of such devices in the laboratory are unknown. Here the authors achiev
Externí odkaz:
https://doaj.org/article/1b35087ef644490da85fcbe6ae8a7dec
Publikováno v:
CEU Repositorio Institucional
Fundación Universitaria San Pablo CEU (FUSPCEU)
Fundación Universitaria San Pablo CEU (FUSPCEU)
Este es el post-print que se ha publicado de forma definitiva en: https://pubs.rsc.org/en/content/articlelanding/2017/ob/c6ob02618d#!divAbstract By comparison with close contact interactions between benzene rings there is a paucity of experimental da
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ccdf8209fe09d4e451c636a8d0bca32
https://doi.org/10.1039/c6ob02618d
https://doi.org/10.1039/c6ob02618d
Autor:
John F. Malone, Steven D. Shepherd, Derek R. Boyd, Christopher C. R. Allen, Deirdre Murphy, Vera Ljubez, Narain D. Sharma
Publikováno v:
Organic & Biomolecular Chemistry. 14:2651-2664
Enantiopure β-hydroxy sulfoxides and catechol sulfoxides were obtained, by chemoenzymatic synthesis, involving dioxygenase-catalysed benzylic hydroxylation or arene cis-dihydroxylation and cis-diol dehydrogenase-catalysed dehydrogenation. Absolute c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71c390cb41dc16af9734b78f9eafa183
https://doi.org/10.1039/c5ob02411k
https://doi.org/10.1039/c5ob02411k
Autor:
Christopher C. R. Allen, Amit Gohil, Colin McRoberts, Peter B. A. McIntyre, Peter N. Horton, Paul J. Stevenson, John F. Malone, Narain D. Sharma, Simon J. Coles, Stewart Floyd, Derek R. Boyd
Publikováno v:
ResearcherID
Using toluene dioxygenase as biocatalyst, enantiopure cis-dihydrodiol and cis-tetrahydrodiol metabolites, isolated as their ketone tautomers, were obtained from meta and ortho methoxyphenols. Although these isomeric phenol substrates are structurally
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfb4cda644f48ed1ab317d1be5408f31
https://doi.org/10.1021/jo5028968
https://doi.org/10.1021/jo5028968
Autor:
Peter Goodrich, Narain D. Sharma, John F. Malone, Gareth McConville, John S. Harrison, Christopher C. R. Allen, Paul J. Stevenson, Derek R. Boyd
Publikováno v:
Chirality. 30(1)
The relative merits of the methods employed to determine enantiomeric excess (ee) values and absolute configurations of chiral arene and alkene cis-1,2-diol metabolites, including boronate formation, using racemic or enantiopure (+) and (-)-2-(1-meth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a9616960c9b0f924527b8805b6aeb2b
https://pubmed.ncbi.nlm.nih.gov/29024058
https://pubmed.ncbi.nlm.nih.gov/29024058
Publikováno v:
Tetrahedron Letters. 52:960-963
Spiro-fused indanones were constructed using a [4 + 2]-cycloaddition approach from α-methylene indanone dienophiles, which were elaborated from 4-chromanone in a number of steps including a key rearrangement process. This type of spiro-fused structu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec2a77a9f94f24a67755c3c5b2ce624f
https://doi.org/10.1016/j.tetlet.2010.12.086
https://doi.org/10.1016/j.tetlet.2010.12.086
Autor:
B. Kelly, Paul J. Stevenson, Derek R. Boyd, K. S. Dunne, Christopher Hardacre, Stuart McGregor, John F. Malone, M. V. Berberian, Narain D. Sharma, M. Kaik
Publikováno v:
Advanced Synthesis & Catalysis. 352:855-868
Enantiopure cis-dihydro-1,2-diol metabolites, obtained from toluene dioxygenase-catalysed cis-dihydroxylation of six monosubstituted benzene substrates, have been converted to their corresponding cis-hexahydro-1,2-diol derivatives by catalytic hydrog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba694b4d644af4f2e0903e4e46ff55d2
https://doi.org/10.1002/adsc.200900818
https://doi.org/10.1002/adsc.200900818
Publikováno v:
Chemistry - A European Journal. 13:5804-5811
A series of ten cis-dihydrodiol metabolites has been obtained by bacterial biotransformation of the corresponding 1,4-disubstituted benzene substrates using Pseudomonas putida UV4, a source of toluene dioxygenase (TDO). Their enantiomeric excess (ee)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8abde48c3c260f439dfb0c49c074d89
https://doi.org/10.1002/chem.200601852
https://doi.org/10.1002/chem.200601852
Publikováno v:
Journal of Chemical Technology & Biotechnology. 82:1072-1081
Factors that control the competition between toluene dioxgenase-catalysed arene cis-dihydroxylation and dehydrogenase-catalysed ketone reduction have been studied, using whole cells of Pseudomonas putida UV and three alkylaryl ketones. The triol meta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::622f833e962205d19a22d2002ae3915a
https://doi.org/10.1002/jctb.1686
https://doi.org/10.1002/jctb.1686
Publikováno v:
The Journal of Organic Chemistry. 71:2277-2282
As part of a search for systems that exhibit intramolecular aromatic edge-to-face interactions, a series of four biaryl compounds containing a phenethyl side chain were prepared. These compounds exist as a slowly interconverting mixture of two atropi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f2c593484d48095367adbe2b4119c08
https://doi.org/10.1021/jo0520902
https://doi.org/10.1021/jo0520902