Zobrazeno 1 - 9
of 9
pro vyhledávání: '"John F. Hoke"'
Autor:
Natalie D. Eddington, Zhongming Liang, John F. Hoke, Julian E. Moreton, Sam H. Haidar, Keith T. Muir
Publikováno v:
Journal of Pharmaceutical Sciences. 86:1278-1282
Remifentanil (Ultiva) is a novel, ultra-short-acting opioid which has recently been approved for use as an analgesic during induction and maintenance of general anesthesia. Esmolol is a short-acting beta-blocker used during surgical procedures to red
Autor:
Valerie Billard, Charles F. Minto, Thomas W. Schnider, Jaap W. Mandema, Talmage D. Egan, David J. Hermann, John F. Hoke, Steven L. Shafer, Pedro L. Gambús, Harry J. M. Lemmens, Katherine H. P. Moore, Keith T. Muir, Elizabeth J. Youngs
Publikováno v:
Anesthesiology. 86:10-23
Background Previous studies have reported conflicting results concerning the influence of age and gender on the pharmacokinetics and pharmacodynamics of fentanyl, alfentanil, and sufentanil. The aim of this study was to determine the influence of age
Publikováno v:
Drug Metabolism Reviews. 23:375-411
As a result of their ability to transport oxygen, PFC emulsions are being investigated for possible use in a wide variety of conditions. The recent FDA approval of F-DA to diminish myocardial ischemia during angioplasty is the first marketing approva
Autor:
Fania Szlam, Keith T. Muir, Cheryl L. Westmoreland, Peter S. Sebel, John F. Hoke, Carl C. Hug
Publikováno v:
Anesthesia and analgesia. 80(5)
Remifentanil is a new potent opioid analgesic that undergoes rapid esterase metabolism. The purpose of this study was to investigate hemodynamic responses to 2-30 micrograms/kg remifentanil (escalating doses) injected as a bolus over 1 min during gen
Autor:
Neil M. Sussman, Kelly K. Antony, John F. Hoke, Lianng Yuh, James M. Elberfeld, Richard A. Okerholm
Publikováno v:
Journal of clinical pharmacology. 33(5)
The pharmacokinetics of vigabatrin were investigated after single and multiple oral doses in two groups of 24 healthy male volunteers. Vigabatrin was well tolerated by the volunteers; headache was the most frequently reported adverse event. There wer
Autor:
William R. Ravis, John F. Hoke
Publikováno v:
Journal of pharmaceutical sciences. 81(4)
Autor:
David J. Hermann, Charles F. Minto, Talmage D. Egan, Steven L. Shafer, Valerie Billard, John F. Hoke, Katherine H. P. Moore, George F. Rich, Harryj M. Lemmens, Pedro L. Gambús, Keith T. Muir, Jaap W. Mandema, Thomas W. Schnider, Elizabeth J. Youngs
Publikováno v:
Survey of Anesthesiology. 41:337
Publikováno v:
Survey of Anesthesiology. 40:32
Autor:
John F. Hoke, William R. Ravis
Publikováno v:
MRS Proceedings. 110
The effect of a perfluorochemical blood substitute (Fluosol-DA 20%) on the disposition kinetics of digoxin in the dog was studied. An intravenous dose of digoxin was administered at either 0.25 or 24 hours following a 30% blood exchange with the dog'