Zobrazeno 1 - 10
of 718
pro vyhledávání: '"John F. Hartwig"'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-9 (2024)
Abstract In pharmaceutical discovery, the “magic methyl” effect describes a substantial improvement in the pharmacological properties of a drug candidate with the incorporation of methyl groups. Therefore, to expedite the synthesis of methylated
Externí odkaz:
https://doaj.org/article/bbc89bcc25a34a7cbc7eee6fa450c10d
Autor:
Zhi-Tao He, John F. Hartwig
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Methods to prepare small, strained rings are sought after due to the importance of such scaffolds in medicinal chemistry. Here, the authors report a palladium-catalyzed α-arylation of cyclopropyl, cyclobutyl and azetidinyl esters.
Externí odkaz:
https://doaj.org/article/0a82f86cdee2462bac4e2ef54fef7ea5
Publikováno v:
ACS Central Science, Vol 3, Iss 8, Pp 895-903 (2017)
Externí odkaz:
https://doaj.org/article/3cab938b508e4e7fbe01c07cc6d69d80
Autor:
Hanna M. Key, Paweł Dydio, Zhennan Liu, Jennifer Y.-E. Rha, Andrew Nazarenko, Vida Seyedkazemi, Douglas S. Clark, John F. Hartwig
Publikováno v:
ACS Central Science, Vol 3, Iss 4, Pp 302-308 (2017)
Externí odkaz:
https://doaj.org/article/58903bcafc4a4090a05d1eaed0844f0f
Publikováno v:
ACS Central Science, Vol 2, Iss 10, Pp 715-724 (2016)
Externí odkaz:
https://doaj.org/article/53267200ba554843b87d640a92bbce0d
Publikováno v:
ACS Central Science, Vol 2, Iss 9, Pp 647-652 (2016)
Externí odkaz:
https://doaj.org/article/a2b49428b1d246518f3f43a1c21ef554
Autor:
John F. Hartwig, Matthew A. Larsen
Publikováno v:
ACS Central Science, Vol 2, Iss 5, Pp 281-292 (2016)
Externí odkaz:
https://doaj.org/article/87f5456a0f7e454a8b89f3dff8f084eb
Autor:
Isaac F. Yu, Jenna L. Manske, Alejandro Diéguez-Vázquez, Antonio Misale, Alexander E. Pashenko, Pavel K. Mykhailiuk, Sergey V. Ryabukhin, Dmitriy M. Volochnyuk, John F. Hartwig
Publikováno v:
Nature Chemistry. 15:685-693
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b59c6234dfc6ddcb10b9dd3bce9c94e5
https://doi.org/10.1038/s41557-023-01159-4
https://doi.org/10.1038/s41557-023-01159-4
Publikováno v:
Journal of the American Chemical Society. 145:3875-3881
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::94e0cc0298943e8a1de1cbd8c063aefc
https://doi.org/10.1021/jacs.2c13054
https://doi.org/10.1021/jacs.2c13054
Autor:
Brandon J. Bloomer, Sean N. Natoli, Marc Garcia-Borràs, Jose H. Pereira, Derek B. Hu, Paul D. Adams, K. N. Houk, Douglas S. Clark, John F. Hartwig
Publikováno v:
Nature Catalysis. 6:39-51
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c9dc640530e9a350ee951fad3d1ecf12
https://doi.org/10.1038/s41929-022-00899-9
https://doi.org/10.1038/s41929-022-00899-9