Zobrazeno 1 - 10
of 196
pro vyhledávání: '"John F. Valliant"'
Autor:
Rowan Swann, Daniel Hernández-Valdés, Luis Rafael Silva, Yusra Mahmood Marfatia, Mohamed E. El-Zaria, Afaf R. Genady, Jacek M. Kwiecien, John F. Valliant, Saman Sadeghi
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract The development of a non-invasive infection-specific diagnostic probe holds the potential to vastly improve early-stage detection of infection, enabling precise therapeutic intervention and potentially reducing the incidence of antibiotic re
Externí odkaz:
https://doaj.org/article/c7b341b4b2b24371bd4940472d18e5aa
Autor:
Kevin Wyszatko, Nancy Janzen, Luis Rafael Silva, Luke Kwon, Teesha Komal, Manuela Ventura, Chitra Venugopal, Sheila K. Singh, John F. Valliant, Saman Sadeghi
Publikováno v:
EJNMMI Research, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Background Cancer stem cells play an important role in driving tumor growth and treatment resistance, which makes them a promising therapeutic target to prevent cancer recurrence. Emerging cancer stem cell-targeted therapies would benefit fr
Externí odkaz:
https://doaj.org/article/492baa18e4e34a2ca48ac359ab64cdc4
Autor:
Afaf R. Genady, Samantha R. Slikboer, Rowan Swann, Kevin Wyszatko, Nancy Janzen, Luis Rafael Silva, Mohamed E. El-Zaria, Saman Sadeghi, John F. Valliant
Publikováno v:
European Journal of Medicinal Chemistry Reports, Vol 4, Iss , Pp 100021- (2022)
Photoacoustic (PA) imaging is a nonradioactive and noninvasive imaging modality that can volumetrically map the distribution of photo-absorbing molecules with deeper tissue penetration than optical modalities. Here, we report on a convenient strategy
Externí odkaz:
https://doaj.org/article/90cffabfae8347119f9b42df3ad7963d
Autor:
Patricia E. Edem, Jean-Philippe Sinnes, Stefanie Pektor, Nicole Bausbacher, Raffaella Rossin, Abdolreza Yazdani, Matthias Miederer, Andreas Kjær, John F. Valliant, Marc S. Robillard, Frank Rösch, Matthias M. Herth
Publikováno v:
EJNMMI Research, Vol 9, Iss 1, Pp 1-8 (2019)
Abstract Background Pretargeted imaging allows the use of short-lived radionuclides when imaging the accumulation of slow clearing targeting agents such as antibodies. The biotin-(strept)avidin and the bispecific antibody-hapten interactions have bee
Externí odkaz:
https://doaj.org/article/3c3a2b2c7f3b4c0690ccc0893c5a719d
Publikováno v:
Synthesis.
Fluoro-benziodoxole, a fluorinated hypervalent iodine (HVI) reagent, has been prepared by fluoride exchange with fluorous- or polystyrene-based sulfonyloxy-benziodoxole precursors. Key to this strategy was the facile O-sulfonylation of a common hydro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe9aef55a34326e142d8942e130c9c46
https://doi.org/10.1055/a-2085-3284
https://doi.org/10.1055/a-2085-3284
Autor:
Charles A. Maitz, Samantha Delaney, Brendon E. Cook, Afaf R. Genady, Rebecca Hoerres, Marina Kuchuk, Georgios Makris, John F. Valliant, Saman Sadeghi, Jason S. Lewis, Heather M. Hennkens, Jeffrey N. Bryan, Brian M. Zeglis
Publikováno v:
Mol Pharm
The last decade has played witness to the creation of a highly effective approach to in vivo pretargeting based on the inverse electron demand Diels-Alder (IEDDA) click ligation between tetrazine (Tz) and trans-cyclooctene (TCO). Despite the steady p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29a6e2a1495044b98593dcf69cc7e61b
https://doi.org/10.1021/acs.molpharmaceut.2c00220
https://doi.org/10.1021/acs.molpharmaceut.2c00220
Autor:
Patricia E. Edem, Jesper T. Jørgensen, Kamilla Nørregaard, Rafaella Rossin, Abdolreza Yazdani, John F. Valliant, Marc Robillard, Matthias M. Herth, Andreas Kjaer
Publikováno v:
Molecules, Vol 25, Iss 3, p 463 (2020)
The bioorthogonal reaction between a tetrazine and strained trans-cyclooctene (TCO) has garnered success in pretargeted imaging. This reaction was first validated in nuclear imaging using an 111In-labeled 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetra
Externí odkaz:
https://doaj.org/article/85b9fd37569b45a5b072f1124512022f
Autor:
Bjoern Wängler, Frank Wuest, Justin J. Bailey, Michael Wagner, John F. Valliant, Melinda Wuest, Carmen Wängler, Ralf Schirrmacher, Atul Bhardwaj
Publikováno v:
Journal of Medicinal Chemistry. 64:15671-15689
Positron emission tomography (PET) imaging of prostate-specific membrane antigen (PSMA) with gallium-68 (68Ga) and fluorine-18 (18F) radiotracers has aroused tremendous interest over the past few years. The use of organosilicon-[18F]fluoride acceptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::651fc934801349cbb702eb39a14ca03f
https://doi.org/10.1021/acs.jmedchem.1c00812
https://doi.org/10.1021/acs.jmedchem.1c00812
Autor:
Srinivas Raman, Douglass Vines, Nathan Perlis, Antonio Finelli, Tony Lam, Peter Chung, Alexandre R. Zlotta, Zhihui Liu, Robert G. Bristow, Padraig Warde, Neil Fleshner, Girish S. Kulkarni, Joelle Helou, Mary Gospodarowicz, Rachel Glicksman, Rosanna Chan, Alejandro Berlin, David Green, Robert J. Hamilton, Charles Catton, David A. Jaffray, John F. Valliant, Ur Metser, Andrew Bayley
Publikováno v:
European Urology. 80:374-382
Background The hypothesis of a curable oligometastatic prostate cancer (PCa) state remains to be clinically-proven. Conventional imaging often fails to localize early recurrences, hampering the potential for radical approaches. Objective We hypothesi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::681f232b7efd58b9c38f2a72ab928e1e
https://doi.org/10.1016/j.eururo.2021.02.031
https://doi.org/10.1016/j.eururo.2021.02.031
Autor:
Alyssa Vito, Hussain Alarabi, Shannon Czorny, Omid Beiraghi, Jeff Kent, Nancy Janzen, Afaf R Genady, Salma A Al-Karmi, Stephanie Rathmann, Zoya Naperstkow, Megan Blacker, Lisset Llano, Paul J Berti, John F Valliant
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0171909 (2017)
[This corrects the article DOI: 10.1371/journal.pone.0167425.].
Externí odkaz:
https://doaj.org/article/6fc4cd242af94f67be03c01544ac5bdf