Zobrazeno 1 - 10
of 149
pro vyhledávání: '"John F Timms"'
Autor:
Vadim Demichev, Pinkus Tober-Lau, Tatiana Nazarenko, Oliver Lemke, Simran Kaur Aulakh, Harry J Whitwell, Annika Röhl, Anja Freiwald, Mirja Mittermaier, Lukasz Szyrwiel, Daniela Ludwig, Clara Correia-Melo, Lena J Lippert, Elisa T Helbig, Paula Stubbemann, Nadine Olk, Charlotte Thibeault, Nana-Maria Grüning, Oleg Blyuss, Spyros Vernardis, Matthew White, Christoph B Messner, Michael Joannidis, Thomas Sonnweber, Sebastian J Klein, Alex Pizzini, Yvonne Wohlfarter, Sabina Sahanic, Richard Hilbe, Benedikt Schaefer, Sonja Wagner, Felix Machleidt, Carmen Garcia, Christoph Ruwwe-Glösenkamp, Tilman Lingscheid, Laure Bosquillon de Jarcy, Miriam S Stegemann, Moritz Pfeiffer, Linda Jürgens, Sophy Denker, Daniel Zickler, Claudia Spies, Andreas Edel, Nils B Müller, Philipp Enghard, Aleksej Zelezniak, Rosa Bellmann-Weiler, Günter Weiss, Archie Campbell, Caroline Hayward, David J Porteous, Riccardo E Marioni, Alexander Uhrig, Heinz Zoller, Judith Löffler-Ragg, Markus A Keller, Ivan Tancevski, John F Timms, Alexey Zaikin, Stefan Hippenstiel, Michael Ramharter, Holger Müller-Redetzky, Martin Witzenrath, Norbert Suttorp, Kathryn Lilley, Michael Mülleder, Leif Erik Sander, PA-COVID-19 Study group, Florian Kurth, Markus Ralser
Publikováno v:
PLOS Digital Health, Vol 1, Iss 1, p e0000007 (2022)
Global healthcare systems are challenged by the COVID-19 pandemic. There is a need to optimize allocation of treatment and resources in intensive care, as clinically established risk assessments such as SOFA and APACHE II scores show only limited per
Externí odkaz:
https://doaj.org/article/8c7d05377e464ce084389ab5400bb7df
Autor:
Christian Eberhardt, Muhunthan Thillai, Robert Parker, Nazneen Siddiqui, Lee Potiphar, Rob Goldin, John F Timms, Athol U Wells, Onn M Kon, Melissa Wickremasinghe, Donald Mitchell, Mark E Weeks, Ajit Lalvani
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0170285 (2017)
Kveim-reagent (Kv) skin testing was a historical method of diagnosing sarcoidosis. Intradermal injection of treated sarcoidosis spleen tissue resulted in a granuloma response at injection site by 4-6 weeks. Previous work indicates proteins as the pos
Externí odkaz:
https://doaj.org/article/b6af6f3e18bf4054b48ff767b45864dd
Autor:
Sumaiyya Thawer, Jennifer Auret, Corinna Schnoeller, Alisha Chetty, Katherine Smith, Matthew Darby, Luke Roberts, Rosie-Marie Mackay, Harry J Whitwell, John F Timms, Jens Madsen, Murray E Selkirk, Frank Brombacher, Howard William Clark, William G C Horsnell
Publikováno v:
PLoS Pathogens, Vol 12, Iss 2, p e1005461 (2016)
Pulmonary epithelial cell responses can enhance type 2 immunity and contribute to control of nematode infections. An important epithelial product is the collectin Surfactant Protein D (SP-D). We found that SP-D concentrations increased in the lung fo
Externí odkaz:
https://doaj.org/article/59be50b199aa4281b57d9c22e9d338b9
Autor:
Eithne Costello, John P. Neoptolemos, John F. Timms, Robert Sutton, William Greenhalf, B. Kevin Park, David A. Tuveson, Stephen P. Pereira, Fiona Campbell, Trevor Cox, Usha Menon, Ian J. Jacobs, Evangelia-O Fourkala, Aleksandra Gentry-Maharaj, Sophia Apostolidou, Darragh P. O'Brien, Rosalind E. Jenkins, Lucy Oldfield, Anthony Evans, Victoria L. Elliott, Claire Jenkinson
Detection of CA1-9 by ELISA in (A) individual time to diagnosis groups and (B) diagnosed samples and controls.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19096ab0e1975897f554b811427938a4
https://doi.org/10.1158/1078-0432.22459275.v1
https://doi.org/10.1158/1078-0432.22459275.v1
Autor:
Eithne Costello, John P. Neoptolemos, John F. Timms, Robert Sutton, William Greenhalf, B. Kevin Park, David A. Tuveson, Stephen P. Pereira, Fiona Campbell, Trevor Cox, Usha Menon, Ian J. Jacobs, Evangelia-O Fourkala, Aleksandra Gentry-Maharaj, Sophia Apostolidou, Darragh P. O'Brien, Rosalind E. Jenkins, Lucy Oldfield, Anthony Evans, Victoria L. Elliott, Claire Jenkinson
Peptides and their fragment ions used in MRM assays for TSP-1.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82586653ba68850b11189fca847fbfd2
https://doi.org/10.1158/1078-0432.22459269.v1
https://doi.org/10.1158/1078-0432.22459269.v1
Autor:
Eithne Costello, John P. Neoptolemos, William Greenhalf, Christopher Halloran, John F. Timms, Phoebe A. Phillips, Quentin Nunes, Rebecca Dawson, Mehdi Jalali, Milton Ashworth, Triantafillos Liloglou, Pedro A. Perez-Mancera, Zipeng Lu, Timothy Andrews, Fiona Campbell, Frances E. Oldfield, Sarah Brumskill, Brian Lane, Anthony Evans, Lawrence N. Barrera
Patient characteristics of UoL serum sample cohorts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13e57539fda1e0c0724f441e7808f996
https://doi.org/10.1158/0008-5472.22424308.v1
https://doi.org/10.1158/0008-5472.22424308.v1
Autor:
John F. Timms, Stephen P. Pereira, Eithne Costello, Usha Menon, Ian J. Jacobs, Ross C. Smith, Alexey Zaikin, Anne Dawnay, Richard Gunu, Oleg Blyuss, Stephane Camuzeaux, Evangelia-Ourania Fourkala, Sophia Apostolidou, Aleksandra Gentry-Maharaj, Claire Jenkinson, Neomal S. Sandanayake, Darragh P. O'Brien
PDF file - 206K, Table S1 Numbers of test positive cases and controls using CA19-9 37 U/mL and CA125 30 U/mL cut-offs Figure S1 Scatter plots showing distribution of CA19-9, CA125, CEACAM1 and REG3A levels against time to diagnosis for discovery set.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19db5b9040eeb056a80b0dfe16f82fe0
https://doi.org/10.1158/1078-0432.22455122
https://doi.org/10.1158/1078-0432.22455122
Autor:
Eithne Costello, John P. Neoptolemos, William Greenhalf, Christopher Halloran, John F. Timms, Phoebe A. Phillips, Quentin Nunes, Rebecca Dawson, Mehdi Jalali, Milton Ashworth, Triantafillos Liloglou, Pedro A. Perez-Mancera, Zipeng Lu, Timothy Andrews, Fiona Campbell, Frances E. Oldfield, Sarah Brumskill, Brian Lane, Anthony Evans, Lawrence N. Barrera
Patient characteristics of samples included on TMAs histologically stained for TNC.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18a730e87d849d6697af26861a9786d7
https://doi.org/10.1158/0008-5472.22424305.v1
https://doi.org/10.1158/0008-5472.22424305.v1
Autor:
Usha Menon, Alexey Zaikin, Ian Jacobs, Steven J. Skates, Mahesh Parmar, John F. Timms, Ranjit Manchanda, Jatinderpal Kalsi, Inés P. Mariño, Aleksandra Gentry-Maharaj, Andy Ryan, Matthew Burnell, Oleg Blyuss
Purpose: In the United Kingdom Collaborative Trial of Ovarian Cancer Screening (UKCTOCS), women in the multimodal (MMS) arm had a serum CA125 test (first-line), with those at increased risk, having repeat CA125/ultrasound (second-line test). CA125 wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2d928eba856b28985914abe3a2f4ca9
https://doi.org/10.1158/1078-0432.c.6527328
https://doi.org/10.1158/1078-0432.c.6527328
Autor:
Eithne Costello, John P. Neoptolemos, William Greenhalf, Christopher Halloran, John F. Timms, Phoebe A. Phillips, Quentin Nunes, Rebecca Dawson, Mehdi Jalali, Milton Ashworth, Triantafillos Liloglou, Pedro A. Perez-Mancera, Zipeng Lu, Timothy Andrews, Fiona Campbell, Frances E. Oldfield, Sarah Brumskill, Brian Lane, Anthony Evans, Lawrence N. Barrera
Although fibrotic stroma forms an integral component of pancreatic diseases, whether fibroblasts programmed by different types of pancreatic diseases are phenotypically distinct remains unknown. Here, we show that fibroblasts isolated from patients w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19972385b09ec376377d8842dc566672
https://doi.org/10.1158/0008-5472.c.6511738
https://doi.org/10.1158/0008-5472.c.6511738