Zobrazeno 1 - 10
of 175
pro vyhledávání: '"John F Pearson"'
Autor:
Barry D Hock, Liping Goddard, Sean A MacPherson, Matthew Strother, David Gibbs, John F Pearson, Judith L McKenzie
Publikováno v:
PLoS ONE, Vol 18, Iss 9, p e0290793 (2023)
The efficacy of PD-1 monoclonals such as pembrolizumab can be modulated by the signals delivered via their Fc region. Tumour/inflammation associated proteases can generate F(ab')2 fragments of therapeutic monoclonals, and subsequent recognition of F(
Externí odkaz:
https://doaj.org/article/5c5343f1c5614282a9d7c4d55c3316c4
Publikováno v:
JMIR Research Protocols, Vol 12, p e37011 (2023)
BackgroundHeart disease and stroke are major and often unheralded causes of serious morbidity and premature death in middle age. Early detection of those most at risk is an urgent unmet need for instituting preventative measures. In an earlier commun
Externí odkaz:
https://doaj.org/article/bd66c9c8c83d4526aa4596d9987813e4
Publikováno v:
PLoS ONE, Vol 17, Iss 6, p e0269541 (2022)
BackgroundCarriage of certain bacterial species may represent potential biomarkers of colorectal cancer (CRC). Prominent among these is Fusobacterium nucleatum. We explored the association of F. nucleatum DNA in stool samples with the presence of col
Externí odkaz:
https://doaj.org/article/34b332f98e114e9e8cf714d4c6555638
Publikováno v:
PLoS ONE, Vol 15, Iss 9, p e0238498 (2020)
There are currently many tools available for capturing and defining the context of one's environment. Digital phenotyping, the use of technology and sensors to capture moment-to-moment behavior, has shown potential in quantifying the lived experience
Externí odkaz:
https://doaj.org/article/ab7904dd251d46be862610b4e7df2c35
Autor:
Ann K Richardson, Margaret J Currie, Bridget A Robinson, Helen Morrin, Yen Phung, John F Pearson, Trevor P Anderson, John D Potter, Logan C Walker
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0118989 (2015)
Findings of polymerase chain reaction (PCR) studies of cytomegalovirus (CMV) and Epstein-Barr virus (EBV) and breast cancer vary, making it difficult to determine whether either, both, or neither virus is causally associated with breast cancer. We in
Externí odkaz:
https://doaj.org/article/48a3d14608c048ca8e472651ee4de17a
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e97102 (2014)
Telomeres are specialised structures that cap the ends of chromosomes. They shorten with each cell division and have been proposed as a marker of cellular aging. Previous studies suggest that early life stressors increase the rate of telomere shorten
Externí odkaz:
https://doaj.org/article/300930e8c0da4a63963c71be97ded7cb
Autor:
Anna P Pilbrow, Lasse Folkersen, John F Pearson, Chris M Brown, Les McNoe, Nancy M Wang, Wendy E Sweet, W H Wilson Tang, Michael A Black, Richard W Troughton, A Mark Richards, Anders Franco-Cereceda, Anders Gabrielsen, Per Eriksson, Christine S Moravec, Vicky A Cameron
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e39574 (2012)
Genome-wide association studies have identified a coronary artery disease (CAD) risk locus in a non-coding region at 9p21.3, the nearest genes being CDKN2A and CDKN2B. To understand the pathways by which this locus might influence CAD susceptibility,
Externí odkaz:
https://doaj.org/article/b227e4d2771f4468a9b7acaf2e702444
Autor:
Ida Amir, Ben J. Thomson, Jenny Herrod, Melanie Anne Souter, Jill Mustard, John F. Pearson, Philip Bird
Publikováno v:
Otology & Neurotology. 44:e133-e139
Autor:
Nasya Thompson, Grace Gatenby, Oliver Waddell, Rachel Purcell, Jacqui Keenan, John F. Pearson, Francis Frizelle, Tamara Glyn
Publikováno v:
ANZ Journal of Surgery.
Autor:
Alexandra J. Noble, John F. Pearson, Alasdair D. Noble, Joseph M. Boden, L. John Horwood, Martin A. Kennedy, Amy J. Osborne
Publikováno v:
Reproduction, Fertility and Development. 34:540-548
Maternal tobacco smoking during pregnancy is a large driver of health inequalities and a higher prevalence of conduct problem (CP) has been observed in exposed offspring. Further, maternal tobacco use during pregnancy can also alter offspring DNA met