Zobrazeno 1 - 10
of 38
pro vyhledávání: '"John F Nomellini"'
Autor:
Christina Farr, John F Nomellini, Evan Ailon, Iryna Shanina, Sassan Sangsari, Lisa A Cavacini, John Smit, Marc S Horwitz
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e65965 (2013)
The HIV/AIDS pandemic remains an enormous global health concern. Despite effective prevention options, 2.6 million new infections occur annually, with women in developing countries accounting for more than half of these infections. New prevention str
Externí odkaz:
https://doaj.org/article/c9b931ab1e474ae08913a53ae747815f
Autor:
John F Nomellini, Carmen Li, Danielle Lavallee, Iryna Shanina, Lisa A Cavacini, Marc S Horwitz, John Smit
Publikováno v:
PLoS ONE, Vol 5, Iss 4, p e10366 (2010)
The development of alternative strategies to prevent HIV infection is a global public health priority. Initial efforts in anti-HIV microbicide development have met with poor success as the strategies have relied on a non-specific mechanism of action.
Externí odkaz:
https://doaj.org/article/fa5791d9039049a8a855322f20046461
Autor:
Jonathan Herrmann, John Smit, John F. Nomellini, Po-Nan Li, Paul G. Bargar, Fatemeh Jabbarpour, Soichi Wakatsuki, Thomas M. Weiss, Lucy Shapiro, Thomas J. Lane
Publikováno v:
Biophysical Journal. 112:1841-1851
Surface layers (S-layers) are paracrystalline, proteinaceous structures found in most archaea and many bacteria. Often the outermost cell envelope component, S-layers serve diverse functions including aiding pathogenicity and protecting against preda
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::858887adad62dbc08e93c72705880fab
https://doi.org/10.1016/j.bpj.2017.04.003
https://doi.org/10.1016/j.bpj.2017.04.003
Autor:
John F. Nomellini, Jonathan Herrmann, Xiaofeng Zhou, Colin J. Comerci, Fatemeh Jabbarpour, Soichi Wakatsuki, Joshua Yoon, Lucy Shapiro, W. E. Moerner, John Smit
Publikováno v:
Biophysical Journal. 118:201a-202a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06ff9016da8d6bb604c9777cf66da1b8
https://doi.org/10.1016/j.bpj.2019.11.1213
https://doi.org/10.1016/j.bpj.2019.11.1213
Publikováno v:
Journal of Virology
Human immunodeficiency virus (HIV) disproportionally infects young women in sub-Saharan Africa. Current HIV-1 prevention options have had limited success among women, suggesting that alternative, female-controlled prevention options need to be develo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b801cc44514b5db3c351097d85c43b5f
https://doi.org/10.1128/jvi.00614-19
https://doi.org/10.1128/jvi.00614-19
Autor:
Colin J. Comerci, John Smit, John F. Nomellini, W. E. Moerner, Xiaofeng Zhou, Lucy Shapiro, Soichi Wakatsuki, Fatemeh Jabbarpour, Joshua Yoon, Jonathan Herrmann
Publikováno v:
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Many bacteria and most archaea possess a crystalline protein surface layer (S-layer), which surrounds their growing and topologically complicated outer surface. Constructing a macromolecular structure of this scale generally requires localized enzyma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20e28244eec001ffcd1089270ce1e3fa
https://pubmed.ncbi.nlm.nih.gov/31227690
https://pubmed.ncbi.nlm.nih.gov/31227690
Autor:
Soichi Wakatsuki, Joshua Yoon, Xiaofeng Zhou, Lucy Shapiro, W. E. Moerner, John Smit, John F. Nomellini, Colin J. Comerci, Fatemeh Jabbarpour, Jonathan Herrmann
Bacteria assemble the cell envelope using localized enzymes to account for growth and division of a topologically complicated surface1–3. However, a regulatory pathway has not been identified for assembly and maintenance of the surface layer (S-lay
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::721df0fe2d0e9ef3216c5f41b2a0e441
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-15 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-15 (2018)
HSV-2 infection is a significant health problem and a major co-morbidity factor for HIV-1 acquisition, increasing risk of infection 2–4 fold. Condom based prevention strategies for HSV-2 and HIV-1 have not been effective at stopping the HIV-1 pande
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bece0fc2083366db324c9de77c9ad4d
http://europepmc.org/articles/PMC5809452
http://europepmc.org/articles/PMC5809452
Publikováno v:
Acta crystallographica. Section F, Structural biology communications. 72(Pt 9)
Protein surface layers are self-assembling, paracrystalline lattices on the surface of many prokaryotes. Surface-layer proteins have not benefited from widespread structural analysis owing to their resistance to crystallization. Here, the successful
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80d9ad03c359941a3deac4543a7fd344
https://pubmed.ncbi.nlm.nih.gov/27599857
https://pubmed.ncbi.nlm.nih.gov/27599857
Autor:
John Smit, Marc S. Horwitz, John F. Nomellini, Christopher J. Lewis, Mark Duval, Lisa A. Cavacini
Publikováno v:
Antimicrobial Agents and Chemotherapy. 55:5547-5552
Innovative methods of prevention are needed to stop the more than two million new HIV-1 infections annually, particularly in women. Local application of anti-HIV antibodies has been shown to be effective at preventing infection in nonhuman primates;
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49c6cff4ac4ca5d58fe5803cc7bdc3c9
https://doi.org/10.1128/aac.00509-11
https://doi.org/10.1128/aac.00509-11