Zobrazeno 1 - 10
of 35
pro vyhledávání: '"John F Kernien"'
Autor:
Tracy M Smith, Madison A Youngblom, John F Kernien, Mohamed A Mohamed, Sydney S Fry, Lindsey L Bohr, Tatum D Mortimer, Mary B O'Neill, Caitlin S Pepperell
Publikováno v:
eLife, Vol 11 (2022)
Tuberculosis (TB), caused by Mycobacterium tuberculosis (M. tb), is a leading cause of death due to infectious disease. TB is not traditionally associated with biofilms, but M. tb biofilms are linked with drug and immune tolerance and there is increa
Externí odkaz:
https://doaj.org/article/5fc89de44b6d43769f6e64d4c6e6a35a
Autor:
J Scott Fites, Michael Gui, John F Kernien, Paige Negoro, Zeina Dagher, David B Sykes, Jeniel E Nett, Michael K Mansour, Bruce S Klein
Publikováno v:
PLoS Pathogens, Vol 14, Iss 5, p e1007073 (2018)
Neutrophils are classically defined as terminally differentiated, short-lived cells; however, neutrophils can be long-lived with phenotypic plasticity. During inflammation, a subset of neutrophils transdifferentiate into a population called neutrophi
Externí odkaz:
https://doaj.org/article/8c19581c703a430a8d5962c8363b744a
Autor:
Chad J Johnson, Jonathan Cabezas-Olcoz, John F Kernien, Steven X Wang, David J Beebe, Anna Huttenlocher, Hamayail Ansari, Jeniel E Nett
Publikováno v:
PLoS Pathogens, Vol 12, Iss 9, p e1005884 (2016)
Neutrophils release extracellular traps (NETs) in response to planktonic C. albicans. These complexes composed of DNA, histones, and proteins inhibit Candida growth and dissemination. Considering the resilience of Candida biofilms to host defenses, w
Externí odkaz:
https://doaj.org/article/9f616fe9cde949c8a40136c673d5fd6f
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Invasive candidiasis frequently involves medical device placement. On the surfaces of these devices, Candida can form biofilms and proliferate in adherent layers of fungal cells surrounded by a protective extracellular matrix. Due in part to this ext
Externí odkaz:
https://doaj.org/article/770d72b070aa463bbcb450f869e1df46
Autor:
Hanxiao Wan, Chad J. Johnson, Jeniel E. Nett, John F. Kernien, Lindsay Kalan, Angela Gibson, Aiping Liu, J. Z. Alex Cheong
Publikováno v:
The ISME Journal
Polymicrobial biofilms are a hallmark of chronic wound infection. The forces governing assembly and maturation of these microbial ecosystems are largely unexplored but the consequences on host response and clinical outcome can be significant. In the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fb68abf8d8af9df2e02f10eee50e19e
http://europepmc.org/articles/PMC8245565
http://europepmc.org/articles/PMC8245565
Autor:
Madison A Youngblom, Tracy M Smith, John F Kernien, Mohamed A Mohamed, Sydney S Fry, Lindsey L Bohr, Tatum D Mortimer, Mary B O'Neill, Caitlin S Pepperell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1604c43a18637e7deed91b97db63b079
https://doi.org/10.7554/elife.78454.sa2
https://doi.org/10.7554/elife.78454.sa2
Autor:
Emily F Eix, Chad J Johnson, Kayla M Wartman, John F Kernien, Jennifer J Meudt, Dhanansayan Shanmuganayagam, Angela L F Gibson, Jeniel E Nett
Publikováno v:
J Infect Dis
Candida auris proliferates and persists on the skin of patients, often leading to health care-associated infections with high mortality. Here, we describe 2 clinically relevant skin models and show that C. auris grows similarly on human and porcine s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::296dba651e265f3271d4c178fa31dcb4
https://europepmc.org/articles/PMC9113498/
https://europepmc.org/articles/PMC9113498/
Autor:
Chad J. Johnson, Taylor J. Schoen, Robert Zarnowski, Michael Kruppa, Jeniel E. Nett, Anna Huttenlocher, John F. Kernien, Mark V. Horton, Zuchao Ma, David L. Williams, Brody D Andes, Douglas W. Lowman
Publikováno v:
mSphere, Vol 6, Iss 3 (2021)
mSphere
mSphere
Candida auris, a recently emergent fungal pathogen, has caused invasive infections in health care settings worldwide. Mortality rates approach 60% and hospital spread poses a public health threat. Compared to other Candida spp., C. auris avoids trigg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ce2abb235540c830b8aec58ad549cdd
https://doi.org/10.1128/msphere.00406-21
https://doi.org/10.1128/msphere.00406-21
Autor:
John F. Kernien, Michael Feldman, Shuying Xu, Paige E. Negoro, Allison K. Scherer, Alex Hopke, Jennifer L. Reedy, Jeniel E. Nett, Daniel Irimia, Natalie J. Alexander, J. Scott Fites, Nida S. Khan, Michael K. Mansour, Zeina Dagher, Richard A. Dutko, Jatin M. Vyas, Natalie J. Atallah, Bruce S. Klein, Adam Viens, David B. Sykes, Jane B Jeffery
Publikováno v:
mBio, Vol 11, Iss 3 (2020)
mBio, Vol 11, Iss 3, p e02043-19 (2020)
mBio, Vol 11, Iss 3, p e02043-19 (2020)
Invasive fungal infections constitute a lethal threat, with patient mortality as high as 90%. The incidence of invasive fungal infections is increasing, especially in the setting of patients receiving immunomodulatory agents, chemotherapy, or immunos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b16557bea15c0fec40fed9416f529256
https://journals.asm.org/doi/10.1128/mBio.02043-19
https://journals.asm.org/doi/10.1128/mBio.02043-19
Autor:
Paige E, Negoro, Shuying, Xu, Zeina, Dagher, Alex, Hopke, Jennifer L, Reedy, Michael B, Feldman, Nida S, Khan, Adam L, Viens, Natalie J, Alexander, Natalie J, Atallah, Allison K, Scherer, Richard A, Dutko, Jane, Jeffery, John F, Kernien, J Scott, Fites, Jeniel E, Nett, Bruce S, Klein, Jatin M, Vyas, Daniel, Irimia, David B, Sykes, Michael K, Mansour
Publikováno v:
mBio
Neutrophils are recognized to represent significant immune cell mediators for the clearance and elimination of the human-pathogenic fungal pathogen Candida. The sensing of fungi by innate cells is performed, in part, through lectin receptor recogniti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::74fa4d90bca69f7df4c3c1c5c4cab341
https://pubmed.ncbi.nlm.nih.gov/32398316
https://pubmed.ncbi.nlm.nih.gov/32398316