Zobrazeno 1 - 10
of 312
pro vyhledávání: '"John F, Keaney"'
Autor:
Amada D. Caliz, Anastassiia Vertii, Vijay Fisch, Soonsang Yoon, Hyung-Jin Yoo, John F. Keaney, Shashi Kant
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Stress-activated mitogen-activated protein kinase kinase 7 (MKK7) is a member of the dual-specificity mitogen-activated protein kinase family. In the human body, MKK7 controls essential physiological processes, including but not limited to proliferat
Externí odkaz:
https://doaj.org/article/62e44ed299d74a1782584d4034c7a9b9
Autor:
Shashi Kant, Siobhan M. Craige, Kai Chen, Michaella M. Reif, Heather Learnard, Mark Kelly, Amada D. Caliz, Khanh-Van Tran, Kasmir Ramo, Owen M. Peters, Marc Freeman, Roger J. Davis, John F. Keaney
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Stress kinases are activated in peripheral ischemic tissues in the presence of vascular diseases. Here the authors show that inhibition of the neural JNK3 kinase improves recovery from hind limb ischemia in animals through activation of the transcrip
Externí odkaz:
https://doaj.org/article/c85d0f19e33747f1a03502a4c952220b
Autor:
Omar Hahad, Natalie Arnold, Jürgen H. Prochaska, Marina Panova-Noeva, Andreas Schulz, Karl J. Lackner, Norbert Pfeiffer, Irene Schmidtmann, Matthias Michal, Manfred Beutel, Philipp S. Wild, John F. Keaney, Andreas Daiber, Thomas Münzel
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Aims: Cigarette smoking is one of the most complex and least understood cardiovascular risk factors. Importantly, differences in the tobacco-related pathophysiology of endothelial dysfunction, an early event in atherogenesis, between circulatory beds
Externí odkaz:
https://doaj.org/article/de4dc1526aa042f6afc8d55c058a1478
Autor:
Kalyn S. Specht, Shashi Kant, Adele K. Addington, Ryan P. McMillan, Matthew W. Hulver, Heather Learnard, Maura Campbell, Sarah R. Donnelly, Amada D. Caliz, Yongmei Pei, Michaella M. Reif, Jacob M. Bond, Anthony DeMarco, Branch Craige, John F. Keaney, Jr., Siobhan M. Craige
Publikováno v:
Molecular Metabolism, Vol 45, Iss , Pp 101160- (2021)
Objective: The immediate signals that couple exercise to metabolic adaptations are incompletely understood. Nicotinamide adenine dinucleotide phosphate oxidase 4 (Nox4) produces reactive oxygen species (ROS) and plays a significant role in metabolic
Externí odkaz:
https://doaj.org/article/42e8a6b1e9fb448a8d2777118c18bc64
Autor:
Thomas Jansen, Miroslava Kvandová, Isabella Schmal, Sanela Kalinovic, Paul Stamm, Marin Kuntic, Marc Foretz, Benoit Viollet, Andreas Daiber, Matthias Oelze, John F. Keaney, Thomas Münzel, Eberhard Schulz, Swenja Kröller-Schön
Publikováno v:
Antioxidants, Vol 10, Iss 12, p 1974 (2021)
Voluntary exercise training is an effective way to prevent cardiovascular disease, since it results in increased NO bioavailability and decreased reactive oxygen species (ROS) production. AMP-activated protein kinase (AMPK), especially its α1AMPK su
Externí odkaz:
https://doaj.org/article/c3092ec682ea409c88933837019f9feb
Autor:
Minwoo Nam, Thomas E. Akie, Masato Sanosaka, Siobhan M. Craige, Shashi Kant, John F. Keaney Jr, Marcus P. Cooper
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Mitochondrial respiration plays a crucial role in determining the metabolic state of brown adipose tissue (BAT), due to its direct roles in thermogenesis, as well as through additional mechanisms. Here, we show that respiration-dependent ret
Externí odkaz:
https://doaj.org/article/a66f49441c9b45cab90f279e62a62661
Autor:
Cheng-Hai Zhang, Pei Wang, Dong-Hai Liu, Cai-Ping Chen, Wei Zhao, Xin Chen, Chen Chen, Wei-Qi He, Yan-Ning Qiao, Tao Tao, Jie Sun, Ya-Jing Peng, Ping Lu, Kaizhi Zheng, Siobhan M. Craige, Lawrence M. Lifshitz, John F. Keaney Jr, Kevin E. Fogarty, Ronghua ZhuGe, Min-Sheng Zhu
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
The molecular basis of the basal tone generated by internal anal sphincters (IAS) is largely unknown. Here, the authors show that the tone arises from a global rise in intracellular Ca2+ in smooth muscle cells via a Ryanodine receptor-TMEM16A-L-type
Externí odkaz:
https://doaj.org/article/b4b7ab0c59cd416bb5911aec0550d29f
Autor:
Miroslava Kvandová, Sanela Rajlic, Paul Stamm, Isabella Schmal, Dominika Mihaliková, Marin Kuntic, Maria Teresa Bayo Jimenez, Omar Hahad, Marta Kollárová, Henning Ubbens, Lea Strohm, Katie Frenis, Georg Daniel Duerr, Marc Foretz, Benoit Viollet, Yue Ruan, Subao Jiang, Qi Tang, Hartmut Kleinert, Steffen Rapp, Adrian Gericke, Eberhard Schulz, Matthias Oelze, John F Keaney, Andreas Daiber, Swenja Kröller-Schön, Thomas Jansen, Thomas Münzel
Publikováno v:
European Journal of Preventive Cardiology.
Aims Environmental stressors such as traffic noise represent a global threat, accounting for 1.6 million healthy life years lost annually in Western Europe. Therefore, the noise-associated health side effects must be effectively prevented or mitigate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d096410f2f507920163645eb05c006b
https://doi.org/10.1093/eurjpc/zwad075
https://doi.org/10.1093/eurjpc/zwad075
Autor:
Paul Stamm, Miroslava Kvandová, Sanela Kalinovic, Isabella Schmal, Dominika Mihaliková, Marin Kuntic, Maria Teresa Bayo Jimenez, Omar Hahad, Marta Kollarová, Henning Ubbens, Lea Strohm, Marc Foretz, Benoit Viollet, Yue Ruan, Subao Jiang, Qi Tang, Hartmut Kleinert, Steffen Rapp, Adrian Gericke, Eberhard Schulz, Matthias Oelze, John F. Keaney, Andreas Daiber, Swenja Kröller-Schön, Thomas Jansen, Thomas Münzel
Publikováno v:
Free Radical Biology and Medicine. 201:11-12
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::274e7c746af975ffb8bfeb36e3fd7ae6
https://doi.org/10.1016/j.freeradbiomed.2023.03.067
https://doi.org/10.1016/j.freeradbiomed.2023.03.067
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