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pro vyhledávání: '"John Ewalt"'
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 17, p 4237 (2019)
G protein-coupled receptors (GPCRs) are critical drug targets. GPCRs convey signals from the extracellular to the intracellular environment through G proteins. Some ligands that bind to GPCRs activate different downstream signaling pathways. G protei
Externí odkaz:
https://doaj.org/article/c07fe29b641c4fd188a107f1397a6858
Publikováno v:
Biophysical and Computational Tools in Drug Discovery ISBN: 9783030852801
A drug-like-molecule library can contain 1023–1060 molecules, among which only approximately 1012 molecules may be synthesized in labs. However, it is still challenging for researchers to find the most promising candidates among the vast number of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b12518a5fcb77238fc144d0180c381d3
https://doi.org/10.1007/7355_2021_124
https://doi.org/10.1007/7355_2021_124
G protein-coupled receptors (GPCRs) are critical drug targets. GPCRs convey signals from the extracellular to the intracellular environment through G proteins. There is evidence that some ligands that bind to the GPCRs activate different downstream s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a29125eb057c8e5211529e037f9e331
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 20, Iss 17, p 4237 (2019)
International Journal of Molecular Sciences, Vol 20, Iss 17, p 4237 (2019)
G protein-coupled receptors (GPCRs) are critical drug targets. GPCRs convey signals from the extracellular to the intracellular environment through G proteins. Some ligands that bind to GPCRs activate different downstream signaling pathways. G protei