Achieving human and machine accessibility of cited data in scholarly publications

Autor: Joan Starr, Eleni Castro, Mercè Crosas, Michel Dumontier, Robert R. Downs, Ruth Duerr, Laurel L. Haak, Melissa Haendel, Ivan Herman, Simon Hodson, Joe Hourclé, John Ernest Kratz, Jennifer Lin, Lars Holm Nielsen, Amy Nurnberger, Stefan Proell, Andreas Rauber, Simone Sacchi, Arthur Smith, Mike Taylor, Tim Clark

Publikováno v: PeerJ Computer Science, Vol 1, p e1 (2015)

Reproducibility and reusability of research results is an important concern in scientific communication and science policy. A foundational element of reproducibility and reusability is the open and persistently available presentation of research data

Externí odkaz: https://doaj.org/article/cccb9a6fed394c4cbbc45a9cac4ea7b3

A Disease-causing Mutation Illuminates the Protein Membrane Topology of the Kidney-expressed Prohibitin Homology (PHB) Domain Protein Podocin

Autor: Judit Tax, Tobias Lamkemeyer, Bernhard Schermer, Thomas Benzing, Linus A. Völker, John Ernest Kratz, Denise Ungrue, Markus M. Rinschen, Eva-Maria Schurek, Martin Höhne, Martin Chalfie, Karl Kunzelmann, Lalida Sirianant

Publikováno v: Schurek, E M, Völker, L A, Tax, J, Lamkemeyer, T, Rinschen, M M, Ungrue, D, Kratz, J E, Sirianant, L, Kunzelmann, K, Chalfie, M, Schermer, B, Benzing, T & Höhne, M 2014, ' A disease-causing mutation illuminates the protein membrane topology of the kidney-expressed prohibitin homology (PHB) domain protein podocin ', Journal of Biological Chemistry, vol. 289, no. 16, pp. 11262-11271 . https://doi.org/10.1074/jbc.M113.521773

Mutations in the NPHS2 gene are a major cause of steroid-resistant nephrotic syndrome, a severe human kidney disorder. The NPHS2 gene product podocin is a key component of the slit diaphragm cell junction at the kidney filtration barrier and part of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cde98c227b8d1c0eb858bdea75c2559
https://doi.org/10.1074/jbc.m113.521773

Making data count

Autor: John Ernest Kratz, Carly Strasser

Publikováno v: Scientific Data. 2

Science is built on a foundation of data. The production and publication of that data should be recognized as valuable scholarship, but data lacks an essential prerequisite for modern-day scholarly recognition—accepted metrics of significance. The

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d395a9d96c5b8a6f3c49155db48dc204

hTERT Gene Amplification and Increased mRNA Expression in Central Nervous System Embryonal Tumors

Autor: Xing Fan, Yves Robitaille, Daniel J. Brat, John Ernest Kratz, Chi V. Dang, Peter C. Burger, Yunyue Wang, T. Albert Moghrabi, Elizabeth J. Perlman, Charles G. Eberhart

Publikováno v: The American Journal of Pathology. 162:1763-1769

High-level gains at 5p15, a chromosomal region including the human telomerase catalytic protein subunit (hTERT) gene, have been documented in several medulloblastomas. We therefore analyzed hTERT gene dosage in a group of medulloblastomas and other e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52d9d7ef9f577c4f68b6c1885e1477ec
https://doi.org/10.1016/s0002-9440(10)64311-8

Microtubule depolymerization in Caenorhabditis elegans touch receptor neurons reduces gene expression through a p38 MAPK pathway

Autor: Alexander Bounoutas, Lesley Emtage, Ken C. Nguyen, Martin Chalfie, John Ernest Kratz, Charles Ma

Microtubules are integral to neuronal development and function. They endow cells with polarity, shape, and structure, and their extensive surface area provides substrates for intracellular trafficking and scaffolds for signaling molecules. Consequent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8377e4bda03dc6f6e0fc19caf0f6bc97
https://europepmc.org/articles/PMC3054000/