Zobrazeno 1 - 10
of 12
pro vyhledávání: '"John E. Romanowski"'
Autor:
Robert M. Q. Shanks, Eric G. Romanowski, John E. Romanowski, Katherine Davoli, Nancy A. McNamara, Jes K. Klarlund
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-8 (2023)
Abstract Biologics are almost exclusively administered systemically, but localized delivery is preferable as it minimizes off-target exposure and allows more aggressive treatments. Topical application of biologics to epithelia is generally ineffectiv
Externí odkaz:
https://doaj.org/article/e531d3377b2743a18c3e0c7a3f926b03
Autor:
Robert M. Q. Shanks, Sarah Atta, Nicholas A. Stella, Chollapadi V. Sundar-Raj, John E. Romanowski, Arman S. Grewal, Hazel Q. Shanks, Sonya M. Mumper, Deepinder K. Dhaliwal, Alex Mammen, Jake D. Callaghan, Rachel C. Calvario, Eric G. Romanowski, Regis P. Kowalski, Michael E. Zegans, Vishal Jhanji
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
IntroductionPseudomonas aeruginosa causes vision threatening keratitis. The LasR transcription factor regulates virulence factors in response to the quorum sensing molecule N-3-oxo-dodecanoyl-L-homoserine lactone. P. aeruginosa isolates with lasR mut
Externí odkaz:
https://doaj.org/article/8ec495ac464e460e8c137979a0a63935
Autor:
Eric G. Romanowski, Kathleen A. Yates, Eric J. Daniels, Brian M. Strem, John E. Romanowski, Regis P. Kowalski
Publikováno v:
Pathogens, Vol 11, Iss 12, p 1485 (2022)
Adenovirus ocular infections are common ocular viral infections seen worldwide, for which there is no approved antiviral therapy available. Ranpirnase is a novel ribonuclease which preferentially degrades tRNA resulting in an inhibition of protein sy
Externí odkaz:
https://doaj.org/article/e6dfd7ae89a540419bd1f53424162552
Autor:
John E. Romanowski, Shannon V. Nayyar, Eric G. Romanowski, Vishal Jhanji, Robert M. Q. Shanks, Regis P. Kowalski
Publikováno v:
Antibiotics, Vol 10, Iss 6, p 721 (2021)
Coagulase-negative staphylococci (CoNS) are frequently occurring ocular opportunistic pathogens that are not easily identifiable to the species level. The goal of this study was to speciate CoNS and document antibiotic susceptibilities from cases of
Externí odkaz:
https://doaj.org/article/826effd6e9ce4a56b37d66e38a7a8145
Autor:
Samantha J. LaCroce, Mollie N. Wilson, John E. Romanowski, Jeffrey D. Newman, Vishal Jhanji, Robert M. Q. Shanks, Regis P. Kowalski
Publikováno v:
Microorganisms, Vol 7, Iss 6, p 163 (2019)
Moraxella is an ocular bacterial pathogen isolated in cases of keratitis, conjunctivitis, and endophthalmitis. Gram-negative brick-shaped diplobacilli from ocular specimens, and slow growth in culture, are early indications of Moraxella ocular infect
Externí odkaz:
https://doaj.org/article/5711d79bf6414860936785a1292e3141
Autor:
Kathleen A. Yates, Nicholas A. Stella, John E Romanowski, Deepinder K. Dhaliwal, Sanya Yadav, Robert M. Q. Shanks, Eric G. Romanowski
Publikováno v:
Curr Eye Res
PURPOSE: Females and males respond differently to a number of systemic viral infections. Differences between females and males with respect to the severity of keratitis caused by Gram-negative bacteria such as Serratia marcescens are less well establ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3564881a4600b1a95e962f0ece7dcaf3
https://europepmc.org/articles/PMC9156527/
https://europepmc.org/articles/PMC9156527/
Autor:
Regis P. Kowalski, Deepinder K. Dhaliwal, Robert M. Q. Shanks, Eric G. Romanowski, John E Romanowski, Vishal Jhanji, Kathleen A. Yates, Alex Mammen
Publikováno v:
Cornea. 39:250-253
Purpose Topical vancomycin 5% (50 mg/mL) has been used for the treatment of methicillin-resistant Staphylococcus aureus (MRSA) keratitis, but patient comfort has many clinicians using lower concentrations. We compared the efficacy of different concen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8e933375e7de7be34cfbbf6d41a0ea1
https://doi.org/10.1097/ico.0000000000002186
https://doi.org/10.1097/ico.0000000000002186
Autor:
Shannon V. Nayyar, John E Romanowski, Vishal Jhanji, Regis P. Kowalski, Robert M. Q. Shanks, Eric G. Romanowski
Publikováno v:
Antibiotics, Vol 10, Iss 721, p 721 (2021)
Antibiotics
Volume 10
Issue 6
Antibiotics
Volume 10
Issue 6
Coagulase-negative staphylococci (CoNS) are frequently occurring ocular opportunistic pathogens that are not easily identifiable to the species level. The goal of this study was to speciate CoNS and document antibiotic susceptibilities from cases of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3274569336ce9b55338856b4fc8efcdc
https://www.mdpi.com/2079-6382/10/6/721
https://www.mdpi.com/2079-6382/10/6/721
Autor:
Robert M. Q. Shanks, Eric G. Romanowski, Anthony J. St. Leger, John E Romanowski, Deepinder K. Dhaliwal, Kathleen A. Yates, Nicholas A. Stella
Publikováno v:
Infect Immun
In this study, we tested the hypothesis that the conserved bacterial IgaA-family protein, GumB, mediates microbial pathogenesis associated with Serratia marcescens ocular infections through regulation of the Rcs stress response system. The role of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2590add828f2b28b4762baa03e838da1
https://pubmed.ncbi.nlm.nih.gov/33820815
https://pubmed.ncbi.nlm.nih.gov/33820815
Autor:
Nicholas A. Stella, Robert M. Q. Shanks, Eric G. Romanowski, Deepinder K. Dhaliwal, John E Romanowski, Kathleen A. Yates
In this study, we tested the hypothesis that the conserved bacterial Rcs stress response system mediates corneal pathogenesis associated withSerratia marcescensocular infections. This was accomplished by modifying Rcs activity using mutant strains. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e9ae6b96244fd08646a1036be8949568
https://doi.org/10.1101/2020.08.07.242446
https://doi.org/10.1101/2020.08.07.242446