An invasive Haemophilus influenzae serotype b infection in an Anglo-Saxon plague victim

Autor: Meriam Guellil, Marcel Keller, Jenna M. Dittmar, Sarah A. Inskip, Craig Cessford, Anu Solnik, Toomas Kivisild, Mait Metspalu, John E. Robb, Christiana L. Scheib

Publikováno v: Genome Biology, Vol 23, Iss 1, Pp 1-27 (2022)

Abstract Background The human pathogen Haemophilus influenzae was the main cause of bacterial meningitis in children and a major cause of worldwide infant mortality before the introduction of a vaccine in the 1980s. Although the occurrence of serotyp

Externí odkaz: https://doaj.org/article/57dcd6e304104b79b4e22fe972e9b4e6

Phylogeography of the second plague pandemic revealed through analysis of historical Yersinia pestis genomes

Autor: Maria A. Spyrou, Marcel Keller, Rezeda I. Tukhbatova, Christiana L. Scheib, Elizabeth A. Nelson, Aida Andrades Valtueña, Gunnar U. Neumann, Don Walker, Amelie Alterauge, Niamh Carty, Craig Cessford, Hermann Fetz, Michaël Gourvennec, Robert Hartle, Michael Henderson, Kristin von Heyking, Sarah A. Inskip, Sacha Kacki, Felix M. Key, Elizabeth L. Knox, Christian Later, Prishita Maheshwari-Aplin, Joris Peters, John E. Robb, Jürgen Schreiber, Toomas Kivisild, Dominique Castex, Sandra Lösch, Michaela Harbeck, Alexander Herbig, Kirsten I. Bos, Johannes Krause

Publikováno v: Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)

The second plague pandemic, caused by Yersinia pestis, started in the 14th century and recurred in Europe until the 18th century. Here, the authors reconstruct ancient Y. pestis genomes from human remains spanning this period, shedding light into the

Externí odkaz: https://doaj.org/article/3862cca408484a71a11606bbdad3d933

Caring for the injured: Exploring the immediate and long-term consequences of injury in medieval Cambridge, England

Autor: Jenna M. Dittmar, Bram Mulder, Anna Tran, Piers D. Mitchell, Peter D. Jones, Sarah A. Inskip, Craig Cessford, John E. Robb

Publikováno v: International Journal of Paleopathology. 40:7-19

To combine paleopathological and biomechanical analysis to reconstruct the impact that a severe skeletal injury had on an individual's ability to function and participate in medieval society.Three medieval individuals from Cambridge, England with ant

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c37dba90d40c536bf4cae3fab3390fc5
https://doi.org/10.1016/j.ijpp.2022.07.004

Ancient herpes simplex 1 genomes reveal recent viral structure in Eurasia

Autor: Meriam Guellil, Lucy van Dorp, Sarah A. Inskip, Jenna M. Dittmar, Lehti Saag, Kristiina Tambets, Ruoyun Hui, Alice Rose, Eugenia D’Atanasio, Aivar Kriiska, Liivi Varul, A. M. H. C. Koekkelkoren, Rimma D. Goldina, Craig Cessford, Anu Solnik, Mait Metspalu, Johannes Krause, Alexander Herbig, John E. Robb, Charlotte J. Houldcroft, Christiana L. Scheib

Publikováno v: Science Advances, 2022, Vol.8(30) [Peer Reviewed Journal]
Science Advances
bioRxiv

Human herpes simplex virus 1 (HSV-1), a life-long infection spread by oral contact, today infects a majority of adults globally1, yet no ancient HSV-1 genomes have yet been published. Phylogeographic clustering of sampled diversity into European, pan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fd82e4a62b81454d9da020623ffea6b
http://dro.dur.ac.uk/37048/

Ancient Yersinia pestis genomes from across Western Europe reveal early diversification during the First Pandemic (541–750)

Autor: Bernd Päffgen, Kirsten I. Bos, Sarah Inskip, Dominique Castex, Joris Peters, Craig Cessford, Andreas Kröpelin, Gunnar U. Neumann, Raphaël Durand, Kathrin Nägele, Jessica S. Bates, Johannes Krause, Bernd Trautmann, Jochen Haberstroh, Michaela Harbeck, Marcel Keller, Peter F. Stadler, Albert Ribera i Lacomba, Maria A. Spyrou, Toomas Kivisild, Alexander Herbig, Michael McCormick, John E. Robb, Claude Raynaud, Christiana L. Scheib, Brigitte Haas-Gebhard

Publikováno v: Keller, Marcel; Spyrou, Maria A.; Scheib, Christiana L.; Neumann, Gunnar U.; Kröpelin, Andreas; Haas-Gebhard, Brigitte; Päffgen, Bernd; Haberstroh, Jochen; Ribera i Lacomba, Albert; Raynaud, Claude; Cessford, Craig; Durand, Raphaël; Stadler, Peter; Nägele, Kathrin; Bates, Jessica S.; Trautmann, Bernd; Inskip, Sarah A.; Peters, Joris; Robb, John E.; Kivisild, Toomas; ... (2019). Ancient Yersinia pestis genomes from across Western Europe reveal early diversification during the First Pandemic (541–750). Proceedings of the National Academy of Sciences of the United States of America-PNAS, 116(25), pp. 12363-12372. National Academy of Sciences NAS 10.1073/pnas.1820447116
Proceedings of the National Academy of Sciences of the United States of America

The first historically documented pandemic caused by Yersinia pestis began as the Justinianic Plague in 541 within the Roman Empire and continued as the so-called First Pandemic until 750. Although paleogenomic studies have previously identified the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9a41a800fdd3098ecf1b9e782c813e6
https://boris.unibe.ch/177461/1/pnas.1820447116.pdf