Zobrazeno 1 - 10 of 247 pro vyhledávání: '"John E. Repine"'
1
Akademický článek
L-ergothioneine reduces nitration of lactoferrin and loss of antibacterial activity associated with nitrosative stress
Autor: Amani Y. Alhalwani, Rachel L. Davey, John E. Repine, J. Alex Huffman
Publikováno v: Biochemistry and Biophysics Reports, Vol 34, Iss , Pp 101447- (2023)
Lactoferrin (LF) is a multifunctional antimicrobial, anti-inflammatory, and antioxidant protein that occurs naturally in mammals, most notably in exocrine gland tissues and fluids, such as in the eye. Nitrosative stress can promote changes to tyrosin
Externí odkaz: https://doaj.org/article/2f2fe5511ce54f11a0eac52fabb93705
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2
Akademický článek
Nasopharyngeal Type-I Interferon for Immediately Available Prophylaxis Against Emerging Respiratory Viral Infections
Autor: Amos C. Lee, Yunjin Jeong, Sumin Lee, Haewook Jang, Allen Zheng, Sunghoon Kwon, John E. Repine
Publikováno v: Frontiers in Immunology, Vol 12 (2021)
In addition to SARS-CoV-2 and its variants, emerging viruses that cause respiratory viral infections will continue to arise. Increasing evidence suggests a delayed, possibly suppressed, type 1 interferon (IFN-I) response occurs early during COVID-19
Externí odkaz: https://doaj.org/article/52f303b87e0a43a7b3ae83c8355e9067
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3
Akademický článek
Brief Glutamine Pretreatment Increases Alveolar Macrophage CD163/Heme Oxygenase-1/p38-MAPK Dephosphorylation Pathway and Decreases Capillary Damage but Not Neutrophil Recruitment in IL-1/LPS-Insufflated Rats.
Autor: Ana Fernandez-Bustamante, Amanda Agazio, Paul Wilson, Nancy Elkins, Luke Domaleski, Qianbin He, Kaily A Baer, Angela F D Moss, Paul E Wischmeyer, John E Repine
Publikováno v: PLoS ONE, Vol 10, Iss 7, p e0130764 (2015)
Glutamine (GLN) attenuates acute lung injury (ALI) but its effect on alveolar macrophages is unknown. We hypothesized that GLN pretreatment would induce the anti-inflammatory CD163/heme oxygenase (HO)-1/p38-MAPK dephosphorylation pathway in alveolar
Externí odkaz: https://doaj.org/article/93844e1dedbf4094a1cd53d0b4ffa234
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4
Depressed prostaglandins and leukotrienes in veterans with Gulf War illness
Autor: Beatrice A. Golomb, Uwe Christians, Hayley J. Koslik, Dwight M. Smith, Jost Klawitter, Jelena Klawitter, Janis B. Ritchie, Nancy D. Elkins, Paul F. Wilson, John E. Repine
Publikováno v: Journal of Environmental Science and Health, Part B. 54:623-639
Background: There is need to understand biological markers and mechanisms in Gulf War illness (GWI).Goal: To examine whether and how eicosanoids – prostaglandins and leukotrienes – are alte...
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::950c0579c921e2d1181c3872c4dc06d3
https://doi.org/10.1080/03601234.2019.1596001
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6
Development of a sandwich ELISA with potential for selective quantification of human lactoferrin protein nitrated through disease or environmental exposure
Autor: Michelle K. Knowles, Amani Y. Alhalwani, John E. Repine, J. Alex Huffman
Publikováno v: Analytical and Bioanalytical Chemistry. 410:1389-1396
Lactoferrin (LF) is an important multifunctional protein that comprises a large fraction of the protein mass in certain human fluids and tissues, and its concentration is often used to assess health and disease. LF can be nitrated by multiple routes,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ab2f1842032d2edf79814d855747e8b
https://doi.org/10.1007/s00216-017-0779-7
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7
Injury characteristics and von Willebrand Factor for the prediction of Acute Respiratory Distress Syndrome in patients with burn injury: Development and Internal Validation
Autor: Luis Ramirez, Elizabeth J. Kovacs, John E. Repine, Joslyn M. Albright, Majid Afshar, Robin C Gagnon, Ellen L. Burnham, Robert C. Dunn, Giora Netzer, Cara Joyce
Publikováno v: Ann Surg
OBJECTIVE: To derive and validate a prediction model for the development of ARDS in burn-injured patients. SUMMARY BACKGROUND DATA: Burn injury carries the highest incidence of acute respiratory distress syndrome (ARDS) among all predisposing conditi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::340055209f8e832f19a8737ab9a8e826
https://europepmc.org/articles/PMC6200654/
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8
Inhalation of two putative Gulf War toxins by mice
Autor: Uwe Christians, Paul Wilson, John E. Repine, Ben Peters, Nancy D. Elkins, Jelena Klawitter, Dwight M. Smith
Publikováno v: Journal of Environmental Science and Health, Part B. 51:366-373
We employed our inhalation methodology to examine whether biomarkers of inflammation and oxidative stress would be produced in mice following inhalation of aerosols containing carbonaceous particles or the vapor of pesticides prevalent during the fir
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a4e6be2b19dd659af54f7429f37f87d
https://doi.org/10.1080/03601234.2016.1142318
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10
Chronic Inflammatory Diseases and the Acute Respiratory Distress Syndrome (ARDS)
Autor: Ana Fernandez-Bustamante, John E. Repine
Publikováno v: Current Pharmaceutical Design. 20:1400-1408
The Acute Respiratory Distress Syndrome (ARDS) is a highly fatal pro-inflammatory oxidative respiratory disease. Relatively recently, the modulating effects of chronic inflammatory processes on ARDS susceptibility have been recognized in a number of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b06902e841c154f3d2e56352ca3755c
https://doi.org/10.2174/13816128113199990561
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