Zobrazeno 1 - 10
of 94
pro vyhledávání: '"John E. Mullinax"'
Autor:
Kate E. Beekman, Danielle K. DePalo, Lily M. Parker, Kelly M. Elleson, John E. Mullinax, Amod A. Sarnaik, Vernon K. Sondak, Jonathan S. Zager
Publikováno v:
Cancer Control, Vol 31 (2024)
Background Radar-guided localization (RGL) offers a wire-free, nonradioactive surgical guidance method consisting of a small percutaneously-placed radar reflector and handheld probe. This study investigates the feasibility, timing, and outcomes of RG
Externí odkaz:
https://doaj.org/article/09dc533c0fad4b4ab04ed742c27070bd
Autor:
Thomas Karadimas, Thien Huong Huynh, Chloe Chose, Guston Zervoudakis, Bryan Clampitt, Sean Lapp, David Joyce, George Douglas Letson, Jonathan Metts, Odion Binitie, John E. Mullinax, Alexander Lazarides
Publikováno v:
Viruses, Vol 16, Iss 7, p 1139 (2024)
Primary bone malignancies, including osteosarcoma (OS), are rare but aggressive. Current OS treatment, involving surgical resection and chemotherapy, has improved survival for non-metastatic cases but remains ineffective for recurrent or metastatic O
Externí odkaz:
https://doaj.org/article/c308cbcdccbf4a6b9246d6e9332da5fa
Autor:
Michael J. Carr, James Sun, William A. Adams, Michelle M. Dugan, Syeda M. H. Naqvi, Youngchul Kim, Jane L. Messina, Ricardo J. Gonzalez, Jonathan S. Zager, John E. Mullinax
Publikováno v:
Cancer Control, Vol 30 (2023)
Background and Objectives Primary cutaneous leiomyosarcoma (cLMS), a rare, typically intradermal tumor, has previously been reported to exhibit an indolent course of disease with zero-to-low risk of local recurrence or distant metastasis. This study
Externí odkaz:
https://doaj.org/article/93775b12258842a69b36239e6c205c1c
Autor:
Shari Pilon-Thomas, Daniel Abate-Daga, Amod A. Sarnaik, James J. Mule, Xiaoqing Yu, Patrick Innamarato, Jamie Blauvelt, Holly Branthoover, Jake Ceccarelli, TJ Langer, MacLean S. Hall, Jamie K. Teer, Sebastian Snedal, Madeline Rodriguez-Valentin, Luz Nagle, Ellen Scott, Ben Schachner, Amy M. Hall, Carolyn J. Rich, Allison D. Richards, Sean J. Yoder, Matthew S. Beatty, Cheryl A. Cox, Jane L. Messina, John E. Mullinax
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 10 (2023)
Background Adoptive cell therapy (ACT) with tumor-infiltrating lymphocytes (TILs) is a promising immunotherapeutic approach for patients with advanced solid tumors. While numerous advances have been made, the contribution of neoantigen-specific CD4+T
Externí odkaz:
https://doaj.org/article/389eec90db77472d949e719312488bf2
Autor:
Aya G. Elmarsafawi, Rebecca S. Hesterberg, Mario R. Fernandez, Chunying Yang, Lancia N.F. Darville, Min Liu, John M. Koomen, Otto Phanstiel IV, Reginald Atkins, John E. Mullinax, Shari A. Pilon-Thomas, Frederick L. Locke, Pearlie K. Epling-Burnette, John L. Cleveland
Publikováno v:
JCI Insight, Vol 8, Iss 18 (2023)
Glutaminolysis is a hallmark of the activation and metabolic reprogramming of T cells. Isotopic tracer analyses of antigen-activated effector CD8+ T cells revealed that glutamine is the principal carbon source for the biosynthesis of polyamines putre
Externí odkaz:
https://doaj.org/article/b2a468345105429b88b1c9a8b533e6c4
Autor:
Patrick Innamarato, Jennifer Morse, Amy Mackay, Sarah Asby, Matthew Beatty, Jamie Blauvelt, Scott Kidd, John E. Mullinax, Amod A. Sarnaik, Shari Pilon-Thomas
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-12 (2021)
Abstract Background Chemotherapy regimens that include the utilization of gemcitabine are the standard of care in pancreatic cancer patients. However, most patients with advanced pancreatic cancer die within the first 2 years after diagnosis, even wh
Externí odkaz:
https://doaj.org/article/32e2ee001c5e4d209c02f66427128c37
Autor:
George Yang, Zhigang Yuan, Kamran Ahmed, Eric A. Welsh, William J. Fulp, Ricardo J. Gonzalez, John E. Mullinax, Douglas Letson, Marilyn Bui, Louis B. Harrison, Jacob G. Scott, Javier F. Torres-Roca, Arash O. Naghavi
Publikováno v:
Translational Oncology, Vol 14, Iss 10, Pp 101165- (2021)
Background: Soft-tissue sarcomas (STS) are heterogeneous with variable response to radiation therapy (RT). Utilizing the radiosensitivity index (RSI) we estimated the radiobiologic ratio of lethal to sublethal damage (α/β), genomic-adjusted radiati
Externí odkaz:
https://doaj.org/article/ddb740cb8b0b41ac990b8c196e3698d1
Autor:
Dandan Li, John E. Mullinax, Taylor Aiken, Hongwu Xin, Gordon Wiegand, Andrew Anderson, Snorri Thorgeirsson, Itzhak Avital, Udo Rudloff
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-15 (2018)
Abstract Background Label-retaining cancer cells (LRCC) have been proposed as a model of slowly cycling cancer stem cells (CSC) which mediate resistance to chemotherapy, tumor recurrence, and metastasis. The molecular mechanisms of chemoresistance in
Externí odkaz:
https://doaj.org/article/a4743a3086ed419bb528b86c0d708e75
Autor:
Arash O. Naghavi, Ricardo J. Gonzalez, Jacob G. Scott, Youngchul Kim, Yazan A. Abuodeh, Tobin J. Strom, Michelle Echevarria, John E. Mullinax, Kamran A. Ahmed, Louis B. Harrison, Daniel C. Fernandez
Publikováno v:
Journal of Contemporary Brachytherapy, Vol 9, Iss 1, Pp 20-29 (2017)
Purpose : Adjuvant brachytherapy (AB) with immediate (IR) and staged reconstruction (SR) are distinct treatment modalities available for patients with recurrent soft tissue sarcoma (STS). Although SR may offer local control and toxicity benefit, it r
Externí odkaz:
https://doaj.org/article/a7e2f2dd73c44d59ba70febb6ea09c87
Autor:
John E. Mullinax, MacLean Hall, Sangeetha Prabhakaran, Jeffrey Weber, Nikhil Khushalani, Zeynep Eroglu, Andrew S. Brohl, Joseph Markowitz, Erica Royster, Allison Richards, Valerie Stark, Jonathan S. Zager, Linda Kelley, Cheryl Cox, Vernon K. Sondak, James J. Mulé, Shari Pilon-Thomas, Amod A. Sarnaik
Publikováno v:
Frontiers in Oncology, Vol 8 (2018)
PurposeAdoptive cell therapy (ACT) using tumor-infiltrating lymphocytes (TIL) for metastatic melanoma can be highly effective, but attrition due to progression before TIL administration (32% in prior institutional experience) remains a limitation. We
Externí odkaz:
https://doaj.org/article/3e14ab4dede64fa39939188dae9bb51b