Zobrazeno 1 - 10
of 16
pro vyhledávání: '"John E. Monahan"'
Autor:
Ping Zhu, Wenlai Zhou, William R. Sellers, Thomas M. Roberts, Frank Stegmeier, John E. Monahan, Vesselina G. Cooke, Sunkyu Kim, Steve G. Kovats, Jing Yuan, Shivang Doshi, David A. Ruddy, Daniel P. Rakiec, Xueliang Gao, Joshua M. Korn, Manav Korpal
Supplementary Figures - PDF file 1014K, F876L mutation in AR rescues androgen signaling and confers resistance to MDV3100 treatment (Figures S1-S15)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::024b4c32a71e374811d4fc06e73ca731
https://doi.org/10.1158/2159-8290.22529795.v1
https://doi.org/10.1158/2159-8290.22529795.v1
Autor:
Diana Graus-Porta, William R. Sellers, Francesco Hofmann, Carlos Garcia-Echeverria, David M. Thomas, Thomas Brümmendorf, Kavitha Venkatesan, John E. Monahan, Jason Borawski, L. Alex Gaither, Mickaël Le Douget, Vincent Bordas, Christopher J. Wilson, Zhi Chen, Yun Zhang, Fang Li, Yao Yao, Astrid Pornon, Louise Barys, Moriko Ito, Christelle Stamm, Simon Wöhrle, Audrey Kauffmann, Vito Guagnano
PDF file - 1.4MB, Response to NVP-BGJ398; FGFR pathway modulation by NVP-BGJ398; NVP-BGJ398 - predictive features; FGFR2-c3 mRNA expression in cell lines and FGFR2 DNA copy number in tumors; FGF19 DNA copy number in CCLE cell lines and FGFR3 DNA copy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::055d71ccbe50a65e308a5319a0af558a
https://doi.org/10.1158/2159-8290.22529469
https://doi.org/10.1158/2159-8290.22529469
Autor:
Alan Huang, John E. Monahan, Robert Schlegel, Daniel P. Rakiec, Angela Tam, Shumei Qiu, Pierce Chow, Richard Ong, Youzhen Wang, David A. Ruddy, Xiaoyan Li, Hung Huynh, Fang Li
Differentially expressed genes (DEGs) identified from RNA-Seq by DeSeq between control and imatinib-treated GIST cell lines.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2168353ec3e91bc8711c987d0230ac23
https://doi.org/10.1158/2159-8290.22530129
https://doi.org/10.1158/2159-8290.22530129
Autor:
Alan Huang, John E. Monahan, Robert Schlegel, Daniel P. Rakiec, Angela Tam, Shumei Qiu, Pierce Chow, Richard Ong, Youzhen Wang, David A. Ruddy, Xiaoyan Li, Hung Huynh, Fang Li
Supplementary Figure and Table Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9684d65770c7d5e5ab6db4553ae7af81
https://doi.org/10.1158/2159-8290.22530138
https://doi.org/10.1158/2159-8290.22530138
Autor:
Diana Graus-Porta, William R. Sellers, Francesco Hofmann, Carlos Garcia-Echeverria, David M. Thomas, Thomas Brümmendorf, Kavitha Venkatesan, John E. Monahan, Jason Borawski, L. Alex Gaither, Mickaël Le Douget, Vincent Bordas, Christopher J. Wilson, Zhi Chen, Yun Zhang, Fang Li, Yao Yao, Astrid Pornon, Louise Barys, Moriko Ito, Christelle Stamm, Simon Wöhrle, Audrey Kauffmann, Vito Guagnano
XML file - 99K, Kinase activity and selectivity for NVP-BGJ398; CCLE cell lines sensitive to NVP-BGJ398; GeneSet expression signatures; FGFR genetic alterations and concomitant mutations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::394b8c19ed3865b26c4b23f7077d34aa
https://doi.org/10.1158/2159-8290.22529463.v1
https://doi.org/10.1158/2159-8290.22529463.v1
Autor:
Ping Zhu, Wenlai Zhou, William R. Sellers, Thomas M. Roberts, Frank Stegmeier, John E. Monahan, Vesselina G. Cooke, Sunkyu Kim, Steve G. Kovats, Jing Yuan, Shivang Doshi, David A. Ruddy, Daniel P. Rakiec, Xueliang Gao, Joshua M. Korn, Manav Korpal
Supplementary Material - PDF file 198K, Supplementary figure legends, tables S1 and S2, and methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::246a37796048c476edaed9ae1f9dd835
https://doi.org/10.1158/2159-8290.22529792.v1
https://doi.org/10.1158/2159-8290.22529792.v1
Autor:
Diana Graus-Porta, William R. Sellers, Francesco Hofmann, Carlos Garcia-Echeverria, David M. Thomas, Thomas Brümmendorf, Kavitha Venkatesan, John E. Monahan, Jason Borawski, L. Alex Gaither, Mickaël Le Douget, Vincent Bordas, Christopher J. Wilson, Zhi Chen, Yun Zhang, Fang Li, Yao Yao, Astrid Pornon, Louise Barys, Moriko Ito, Christelle Stamm, Simon Wöhrle, Audrey Kauffmann, Vito Guagnano
XML file - 56K, High throughput pharmacological screen of BGJ398 in 517 cancer cell lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2881a9c58817a03993b13427e5d262a1
https://doi.org/10.1158/2159-8290.22529466.v1
https://doi.org/10.1158/2159-8290.22529466.v1
Autor:
Francesco Hofmann, William R. Sellers, Clive McCarthy, Markus Wartmann, Peter Drueckes, Dorothea Haasen, Jutta Blank, Michael D. Jones, John E. Monahan, David A. Ruddy, Emily Buck, Joseph Schoepfer, Sabrina Wagner, Brent A. Appleton, Pascal Furet, Elisa Degenkolbe, Ralph Tiedt
Supplementary Figures 1-2, Tables 1-4, Methods from A Drug Resistance Screen Using a Selective MET Inhibitor Reveals a Spectrum of Mutations That Partially Overlap with Activating Mutations Found in Cancer Patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3613711d07dd229641d5f5262ca31848
https://doi.org/10.1158/0008-5472.22388450.v1
https://doi.org/10.1158/0008-5472.22388450.v1
Autor:
Anupama Reddy, Joseph D Growney, Nick S Wilson, Caroline M Emery, Jennifer A Johnson, Rebecca Ward, Kelli A Monaco, Joshua Korn, John E Monahan, Mark D Stump, Felipa A Mapa, Christopher J Wilson, Janine Steiger, Jebediah Ledell, Richard J Rickles, Vic E Myer, Seth A Ettenberg, Robert Schlegel, William R Sellers, Heather A Huet, Joseph Lehár
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0146635 (2016)
Externí odkaz:
https://doaj.org/article/59c3f93f2d5c4482aef340a64a791f66
Autor:
Anupama Reddy, Joseph D Growney, Nick S Wilson, Caroline M Emery, Jennifer A Johnson, Rebecca Ward, Kelli A Monaco, Joshua Korn, John E Monahan, Mark D Stump, Felipa A Mapa, Christopher J Wilson, Janine Steiger, Jebediah Ledell, Richard J Rickles, Vic E Myer, Seth A Ettenberg, Robert Schlegel, William R Sellers, Heather A Huet, Joseph Lehár
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0138486 (2015)
Death Receptor 5 (DR5) agonists demonstrate anti-tumor activity in preclinical models but have yet to demonstrate robust clinical responses. A key limitation may be the lack of patient selection strategies to identify those most likely to respond to
Externí odkaz:
https://doaj.org/article/65b59ba5d911495fa33f7b9acb527174