Zobrazeno 1 - 10
of 25
pro vyhledávání: '"John E. Mata"'
Autor:
Bernard Séguin, Guangheng Li, Nicolle E. Hofmann, Atiya Mansoor, Shay Bracha, Charles Keller, Elaine T. Huang, Lara E. Davis, Marc M. Loriaux, Jinu Abraham, John E. Mata, Stuart C. Helfand, Kevin Marley, Jeffrey W. Tyner
Publikováno v:
Pediatric Blood & Cancer. 60:1313-1319
Osteosarcomaisthemostcommonmalignantbonetumor,yettheincidenceofosteosarcomaislowenoughtoposeasignificantbarrierto the timely completion of traditionally designed clinical trials.While research laboratories continue to investigate the underlyingmecha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89d670107e6a08ec01bcc7ed6689cd80
https://doi.org/10.1002/pbc.24512
https://doi.org/10.1002/pbc.24512
Autor:
Carole Jubert, George S. Bailey, William G. Tracewell, Kenneth W. Turteltaub, Cliff Pereira, Roderick H. Dashwood, John E. Mata, Graham Bench, David E. Williams
Publikováno v:
Cancer Prevention Research. 2:1015-1022
Chlorophyll (Chla) and chlorophyllin (CHL) were shown previously to reduce carcinogen bioavailability, biomarker damage, and tumorigenicity in trout and rats. These findings were partially extended to humans, where CHL reduced excretion of aflatoxin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfe9a068fbae9c3b4ef1c5a32b4074c8
https://doi.org/10.1158/1940-6207.capr-09-0099
https://doi.org/10.1158/1940-6207.capr-09-0099
Autor:
James E. Summerton, Arhie Reid Tyson, Leslie A. Dyal, Scott B. Gustafson, John E. Mata, Margorie E. Slauson, Rosita Rodriguez-Proteau, Christiane V Loehr
Publikováno v:
Nanomedicine: Nanotechnology, Biology and Medicine. 3:297-305
Solid tumors often display metabolic abnormalities that consistently produce low pH in the extracellular space of poorly perfused tissue. These acidic regions may provide a mechanism for drug targeting. Peptides have been designed in such a manner th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49aae939b2feee101d0d0da7dbb46575
https://doi.org/10.1016/j.nano.2007.08.001
https://doi.org/10.1016/j.nano.2007.08.001
Autor:
Michael R. Bishop, Carol R. Angle, Stanley A. Swanson, Stefano R. Tarantolo, John E. Mata, Patrick L. Iversen
Publikováno v:
Journal of Toxicology: Clinical Toxicology. 38:383-387
Phosphorothioate oligonucleotides, in general, possess properties that could be utilized in the development of therapeutic heavy metal chelators.Iron excretion was measured in 16 patients participating in studies to test the safety of OL(1)p53, a 20-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68afa0dad955fa01a4055274fa604e83
https://doi.org/10.1081/clt-100100947
https://doi.org/10.1081/clt-100100947
Autor:
Todd J. Page, John E. Mata, Patrick L. Iversen, James R. Neff, Julia A. Bridge, Justin C Siebler
Publikováno v:
Experimental Cell Research. 252:41-49
Telomerase is a ribonucleoprotein that adds 5′-d(TTAGGG)-3′ hexameric repeats onto the 3′ ends of chromosomes. High telomerase activity has been associated with immortal cells, transformed cells, mitogenic stimulation, and proliferative disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31ec10244f2f4189e51f8c8874ff4bd8
https://doi.org/10.1006/excr.1999.4613
https://doi.org/10.1006/excr.1999.4613
Autor:
Patric L. Iversen, Atsushi Takeda, Shoji Okada, Mai Suzuki, John E. Mata, Harumi Hisada, Manuchair Ebadi
Publikováno v:
ResearcherID
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a52280ee39976f42351a6625e1b06481
https://doi.org/10.1002/(sici)1520-670x(1998)11:1<1::aid-jtra1>3.0.co
https://doi.org/10.1002/(sici)1520-670x(1998)11:1<1::aid-jtra1>3.0.co
Autor:
John E. Mata, Jennifer M. Simpson, Bernard Séguin, Kevin Marley, William G. Tracewell, Stuart C. Helfand, Shay Bracha, Lisa Brownlee
Publikováno v:
Journal of Experimental & Clinical Cancer Research : CR
Background Osteosarcoma in dogs and humans share many similarities and the dog has been described as an excellent model to study this disease. The median survival in dogs has not improved in the last 25 years. Taurolidine has been shown to be cytotox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6e4af0ae573f774ddd1cc0f67438ca6
https://doi.org/10.1186/1756-9966-32-74
https://doi.org/10.1186/1756-9966-32-74
Publikováno v:
Journal of Drug Targeting. 2:477-485
5' cholesteryl-conjugated phosphorothioate oligodeoxynucleotides with sequence complementary to the rat CYP2B1 mRNA were evaluated in adult male Sprague-Dawley rats for their pharmacokinetic properties, toxicity, and ability to modulate CYP2B1 expres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e6d267371856afab3dc968625c9e557
https://doi.org/10.3109/10611869509015917
https://doi.org/10.3109/10611869509015917
Autor:
Lara E, Davis, Nicolle E, Hofmann, Guangheng, Li, Elaine T, Huang, Marc M, Loriaux, Shay, Bracha, Stuart C, Helfand, John E, Mata, Kevin, Marley, Atiya, Mansoor, Jeffrey W, Tyner, Jinu, Abraham, Bernard, Séguin, Charles, Keller
Publikováno v:
Pediatric bloodcancer. 60(8)
Effective targeted therapies are needed in sarcomas, but the biological heterogeneity of these tumors has presented a challenge to clinical integration of small molecule inhibitors in sarcoma treatment. Here we outline a process to personalize therap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6afc69a3183d47514bff8ded0f13bf1b
https://pubmed.ncbi.nlm.nih.gov/23526721
https://pubmed.ncbi.nlm.nih.gov/23526721
Autor:
S.F. Pang, Chiu-Yin Kwan, Alice Y.-C. Liu, Peter D. Kitchener, Edwin E. Daniel, Nien-Tze Chang, Manuchair Ebadi, Patrick L. Iversen, J.-P. Bourreau, Bao-Cun Sun, John E. Mata, Y. Song, Guo-Zhang Jin
Publikováno v:
Neurosignals. 1:I-V
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9eac77abeb8b578441049ef10754998b
https://doi.org/10.1159/000109341
https://doi.org/10.1159/000109341