Zobrazeno 1 - 10
of 35
pro vyhledávání: '"John E. Hopper"'
Publikováno v:
Journal of Clinical Immunology. 20:123-137
As a marker of in vivo B-cell activity, urine levels of free light chain (FLC) were measured twice weekly by radioimmunassay (RIA) and correlated with disease activity over periods of 5–10 months in seven patients with systemic lupus erythematousus
Autor:
Aaron H. Konstam, Larry Glenn, Pat Aufderheide, John E. Hopper, Richard Stewart, Iris F. Molotsky
Publikováno v:
Academe. 82:66
Autor:
John E. Hopper
Publikováno v:
Blood. 50:203-211
Previous studies have presented evidence of shared idiotypic antigenic determinants located within the variable (VH) region of the heavy chains of monotypic IgMlambda and IgGkappa isolated from the serum of an individual patient, Bro, with Waldenstro
Autor:
Wayne Miller, Mary Ellen Gaeke, James W. Vardiman, John E. Hopper, Janet D. Rowley, Maria Medenica
Publikováno v:
Blood. 57:634-641
The aggressive clinical course and the distinctive histologic, cytochemical, and cytogenetic features of an adult non-Sezary T-cell lymphoma with suppressor activity have been investigated. Morphological and ultrastructural analysis of neoplastic cel
Publikováno v:
The Journal of Immunology. 122:2007-2010
The N-terminal sequence analyses were performed on the heavy (H) and light (L) chains of the idiotypically identical IgMκ and IgGκ paraproteins isolated from the serum of patient, Cam. The N-terminal 39 residues of the κ chains of the IgM and IgG
Publikováno v:
Mechanisms of Ageing and Development. 23:11-19
Age-related changes in the processes involved in T cell dependent polyclonal B cell activation in man were studied by comparing immunoglobulin (Ig) produced in autologous T:B (E + :E − ) cell cultures of young and old donor pairs with Ig produced i
Publikováno v:
Cancer. 44:630-644
Karyotypic abnormalities were detected in the malignant cells of 6 of 18 patients with multiple myeloma (MM). Six patients with benign monoclonal gammopathy, one with amyloidosis of immunoglobulin origin, and two with Waldenstrom's macroglobulinemia
Autor:
J. Marie Haren, John E. Hopper
Publikováno v:
Clinical Immunology and Immunopathology. 17:43-54
Patient N.R. with mycosis fungoides and Sezary Syndrome is described. Surface marker analysis of the N.R. Sezary cells revealed T-cell characteristics. As expected for thymic-derived lymphocytes, the N.R. Sezary cells failed to produce Ig in pokeweed
Publikováno v:
The Journal of Immunology. 122:2000-2006
The results of a comparative idiotypic analysis of multiple Ig paraproteins isolated from the serum of an individual patient, Ca, with Sjögren's syndrome and Waldenström's macroglobulinemia are reported. At initial presentation, Ca serum was found
Autor:
John E. Hopper, J.Donald Capra
Publikováno v:
Immunochemistry. 13:995-999
Two paraproteins (IgM lambda, IgG3 kappa) obtained from a single individual's sera had been previously shown to possess highly similar, if not identical idiotypic determinants. Preliminary structural analysis indicated that the mu and gamma chains be