Zobrazeno 1 - 10
of 256
pro vyhledávání: '"John E. Hearst"'
Autor:
Y Gao, Anat A. Herskovits, Joanne Y.H. Lim, Adam Sampson-Johannes, David N. Cook, Martin A. Giedlin, John E. Hearst, Keith S. Bahjat, W Liu, William S. Luckett, D Kapadia, A Stassinopoulos, Pamela Schnupf, Thomas W. Dubensky, G Castro, H. G. Archie Bouwer, Dirk G. Brockstedt, M Leong, Daniel A. Portnoy
Publikováno v:
Nature Medicine. 11:853-860
We developed a new class of vaccines, based on killed but metabolically active (KBMA) bacteria, that simultaneously takes advantage of the potency of live vaccines and the safety of killed vaccines. We removed genes required for nucleotide excision r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b50e6b94dcb77d5fbcbc21970260631
https://doi.org/10.1038/nm1276
https://doi.org/10.1038/nm1276
Autor:
Shaila Ahmed, Sherly Bellevue, John E. Hearst, Gillian Pereira, Wilma A. Saffran, Teleka Patrick, Marie Alberti, Wendy Sanchez, Sandra Thomas
Publikováno v:
Journal of Biological Chemistry. 279:36462-36469
The repair of psoralen interstrand cross-links in the yeast Saccharomyces cerevisiae involves the DNA repair groups nucleotide excision repair (NER), homologous recombination (HR), and post-replication repair (PRR). In repair-proficient yeast cells c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fde2ff661fc9525b68816cf345d1c4b5
https://doi.org/10.1074/jbc.m402323200
https://doi.org/10.1074/jbc.m402323200
Autor:
John E. Hearst, David L. Jaye, Sabina A. Alexander, Levan J. Lezhava, John W. Gorechlad, John D. Roback, Christopher D. Hillyer, Stephen Mittelstaedt, Mohammad S. Hossain, Sohel Talib, Edmund K. Waller
Publikováno v:
The Journal of Immunology. 171:6023-6031
Infusion of donor antiviral T cells can provide protective immunity for recipients of hemopoietic progenitor cell transplants, but may cause graft-vs-host disease (GVHD). Current methods of separating antiviral T cells from the alloreactive T cells t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d30369a78f4f0182e97b804fb6329f1d
https://doi.org/10.4049/jimmunol.171.11.6023
https://doi.org/10.4049/jimmunol.171.11.6023
Publikováno v:
Journal of Molecular Biology. 308:15-26
The single-crystal structures are presented for two DNA sequences with the thymine bases covalently cross-linked across the complementary strands by 4′-hydroxymethyl-4,5′,8-trimethylpsoralen (HMT). The HMT-adduct of d(CCGCTAGCGG) forms a psoralen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc8d9c92e2fb95038c7d25e1c0b1580d
https://doi.org/10.1006/jmbi.2001.4567
https://doi.org/10.1006/jmbi.2001.4567
Publikováno v:
The Journal of Immunology. 163:5145-5156
Donor leukocyte infusions after allogeneic bone marrow transplantation can provide a curative graft-vs-leukemia (GVL) effect, but there is a significant risk of graft-vs-host (GVH) disease. A simple and effective method for controlling the fate of na
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f4ada6134f08a442bec69cebef0c305
https://doi.org/10.4049/jimmunol.163.9.5145
https://doi.org/10.4049/jimmunol.163.9.5145
Autor:
John E. Hearst, R. A. Harris
Publikováno v:
Journal of Polymer Science Part C: Polymer Symposia. 15:331-333
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50c4b39c50e965a24fc88accd6affeb4
https://doi.org/10.1002/polc.5070150127
https://doi.org/10.1002/polc.5070150127
Autor:
John E. Hearst, Thomas C. Bishop
Publikováno v:
The Journal of Physical Chemistry B. 102:6433-6439
Most of the DNA in a eucaryotic cell nucleus is accurately described as an extremely long thin fiber which is smoothly folded by histones into a thicker fiber called the 30 nm fiber. For the DNA to remain biologically functional, the 30 nm fiber must
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::36b296973c2120454936b4440dae55aa
https://doi.org/10.1021/jp980909s
https://doi.org/10.1021/jp980909s
Publikováno v:
The Journal of Chemical Physics. 105:714-731
We have developed a new statistical mechanical theory for wormlike chains and elastic rods which will account for deformations of bending, twisting, shear, and axial extension/stretching. We have derived a Fokker–Planck equation for Green’s funct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e87d78b62e8842e74ee1a15236905358
https://doi.org/10.1063/1.471927
https://doi.org/10.1063/1.471927
Autor:
John E. Hearst, Gregory A. Armstrong
Publikováno v:
The FASEB Journal. 10:228-237
The two major functions of carotenoids in photosyn- thetic microorganisms and plants are the absorption of energy for use in photosynthesis and the protection of chlorophyll from photodamage. The synthesis of vari- ous carotenoids, therefore, is a cr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3afd5c7f1fceee27126a8a8b6091d44
https://doi.org/10.1096/fasebj.10.2.8641556
https://doi.org/10.1096/fasebj.10.2.8641556
Publikováno v:
Molecular Microbiology. 19:101-112
Summary Genes acrAB encode a multidrug efflux pump in Escherichia coli. We have previously reported that transcription of acrAB is increased under general stress conditions (i.e. 4% ethanol, 0.5 M NaCl, and the stationary phase in Luria-Bertanl mediu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f3174c9171e65ac0927486fc2a24759
https://doi.org/10.1046/j.1365-2958.1996.357881.x
https://doi.org/10.1046/j.1365-2958.1996.357881.x