Zobrazeno 1 - 10 of 289 pro vyhledávání: '"John E. Coligan"'
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Akademický článek
Aberrant Development of Thymocytesin Mice Lacking Laminin-2
Autor: William J. Magner, Andrew C. Chang, Jennie Owens, M-J. P. Hong, Andrew Brooks, John E. Coligan
Publikováno v: Clinical and Developmental Immunology, Vol 7, Iss 2-4, Pp 179-193 (2000)
Externí odkaz: https://doaj.org/article/d5b44317aa8041f59b3b73ad75828c6e
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Dendritic cells expressing immunoreceptor CD300f are critical for controlling chronic gut inflammation
Autor: Linjie Tian, Jacquice Davis, Ha-Na Lee, Yasmine Belkaid, Nicolas Bouladoux, Konrad Krzewski, Mariam Quinones, John E. Coligan
Publikováno v: Journal of Clinical Investigation. 127:1905-1917
Proinflammatory cytokine overproduction and excessive cell death, coupled with impaired clearance of apoptotic cells, have been implicated as causes of failure to resolve gut inflammation in inflammatory bowel diseases. Here we have found that dendri
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a24ef676a5fab96a48b59246e13ad0bc
https://doi.org/10.1172/jci89531
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4
Natural killer cell activity and dysfunction in Hermansky-Pudlak syndrome
Autor: Bernadette R. Gochuico, William A. Gahl, John E. Coligan, Konrad Krzewski, Yousuke Murakami, Melissa A. Merideth, Aleksandra Gil-Krzewska, Kevin J. O'Brien, Giovanna Peruzzi, Andrew R. Cullinane
Publikováno v: British Journal of Haematology. 176:118-123
Hermansky-Pudlak syndrome (HPS) encompasses disorders with abnormal function of lysosomes and lysosome-related organelles, and some patients who develop immunodeficiency. The basic mechanisms contributing to immune dysfunction in HPS are ill-defined.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a29777f88c9baea80e136089b9907779
https://doi.org/10.1111/bjh.14390
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5
Lipopolysaccharide-Induced CD300b Receptor Binding to Toll-like Receptor 4 Alters Signaling to Drive Cytokine Responses that Enhance Septic Shock
Autor: Konrad Krzewski, Yousuke Murakami, David H. Margulies, Jonathan M. Street, John E. Coligan, Chen-Feng Qi, Linjie Tian, Mirna Pena, Peter S.T. Yuen, Ha-Na Lee, Oliver H. Voss
Publikováno v: Immunity. 44:1365-1378
Receptor CD300b is implicated in regulating the immune response to bacterial infection by an unknown mechanism. Here, we identified CD300b as a lipopolysaccharide (LPS)-binding receptor and determined the mechanism underlying CD300b augmentation of s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::da8aca7bc20dd5af7ec7ce07ae1b1ed7
https://doi.org/10.1016/j.immuni.2016.05.005
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6
Enhanced efferocytosis by dendritic cells underlies memory T-cell expansion and susceptibility to autoimmune disease in CD300f-deficient mice
Autor: Oliver H. Voss, Chen-Feng Qi, Linjie Tian, Ha-Na Lee, Yousuke Murakami, Seung-Chul Choi, Sengottuvelu M, Konrad Krzewski, John E. Coligan
Publikováno v: Cell Death & Differentiation. 23:1086-1096
Homeostasis requires the immunologically silent clearance of apoptotic cells before they become pro-inflammatory necrotic cells. CD300f (CLM-1) is a phosphatidylserine receptor known to positively regulate efferocytosis by macrophages, and CD300f gen
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a29a2a620af4fc5c0c2af02ebef08125
https://doi.org/10.1038/cdd.2015.161
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7
Liposome Preparation for the Analysis of Lipid-Receptor Interaction and Efferocytosis
Autor: Linjie Tian, Oliver H. Voss, John E. Coligan, Ha-Na Lee, Konrad Krzewski
Publikováno v: Current Protocols in Immunology
Efficient phagocytosis of apoptotic cells (efferocytosis) is essential for immune homeostasis. Phospholipids exposed on the surface of apoptotic cells, such as phosphatidylserine, supply important "eat-me" signals. Liposomes are lipid bilayer vesicle
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2604985dd7e2d8bac669fae77c41558
https://pubmed.ncbi.nlm.nih.gov/29512142
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8
CD300f associates with IL-4 receptor α and amplifies IL-4–induced immune cell responses
Autor: Aroa Ejarque-Ortiz, Linjie Tian, Joan Sayós, Netali Morgenstern-Ben-Baruch, Itay Moshkovits, Danielle Karo-Atar, Hadar Reichman, Alon Y. Hershko, Michal Itan, Perri Rozenberg, Ariel Munitz, Dana Shik, John E. Coligan
Publikováno v: Proceedings of the National Academy of Sciences. 112:8708-8713
IL-4 receptor (R) α, the common receptor chain for IL-4 and IL-13, is a critical component in IL-4- and IL-13-mediated signaling and subsequent effector functions such as those observed in type 2 inflammatory responses. Nonetheless, the existence of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70d835c6a8ab776d8032777baab0f7ab
https://doi.org/10.1073/pnas.1507625112
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9
The ITIM-containing receptor LAIR1 is essential for acute myeloid leukaemia development
Autor: Xiangshu Xiao, Xin Han, M. James You, Robert H. Collins, Baijun Dong, Cheng Cheng Zhang, Jeffrey W. Tyner, Yuqi Fan, Changhao Cui, Mi Deng, Xunlei Kang, John E. Coligan, Fuchun Xie, Zhigang Lu
Publikováno v: Nature cell biology
Conventional strategies are not particularly successful in the treatment of leukaemia, and identification of signalling pathways crucial to the activity of leukaemia stem cells will provide targets for the development of new therapies. Here we report
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b475b7a0c030a2cf5a1ea697f52747c
https://doi.org/10.1038/ncb3158
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