Zobrazeno 1 - 6
of 6
pro vyhledávání: '"John E. Brogie"'
Autor:
John E. Brogie, David H. Price
Publikováno v:
Nucleic Acids Research
The 7SK small nuclear ribonucleoprotein (snRNP) plays a central role in RNA polymerase II elongation control by regulating the availability of active P-TEFb. We optimized conditions for analyzing 7SK RNA by SHAPE and demonstrated a hysteretic effect
Autor:
Kyle A. Nilson, Jiannan Guo, John E. Brogie, David H. Price, Michael E. Turek, Elizabeth Delaney, Donal S. Luse
Publikováno v:
Molecular Cell. 59(4):576-587
The Cdk7 subunit of TFIIH phosphorylates RNA polymerase II (Pol II) during initiation, and, while recent studies show that inhibition of human Cdk7 negatively influences transcription, the mechanisms involved are unclear. Using in vitro transcription
Stress from Nucleotide Depletion Activates the Transcriptional Regulator HEXIM1 to Suppress Melanoma
Autor:
Alvaro C. Laga, John M. Asara, Howard Y. Chang, Justin L. Tan, Brian T. Do, Leonard I. Zon, Anne Bothmer, Richard M. White, David H. Price, Ng Shyh-Chang, Ryan A. Flynn, Nicole Pandell, Song Yang, Violaine Saint-André, Yoon Jung Kim, Zi Peng Fan, Koh Fujinaga, Elliott J. Hagedorn, Serine Avagyan, Tae Hoon Kim, Cristina Santoriello, B. Matija Peterlin, Ellen van Rooijen, John G. Clohessy, John E. Brogie, Richard A. Young, Celeste B. Greer, Yi Zhou, Pier Paolo Pandolfi, Rachel D. Fogley, Julien Ablain
Publikováno v:
Molecular Cell
Molecular Cell, 2016, 62 (1), pp.34-46. ⟨10.1016/j.molcel.2016.03.013⟩
Molecular Cell, Elsevier, 2016, 62 (1), pp.34-46. ⟨10.1016/j.molcel.2016.03.013⟩
PMC
Molecular cell, vol 62, iss 1
Molecular Cell, 2016, 62 (1), pp.34-46. ⟨10.1016/j.molcel.2016.03.013⟩
Molecular Cell, Elsevier, 2016, 62 (1), pp.34-46. ⟨10.1016/j.molcel.2016.03.013⟩
PMC
Molecular cell, vol 62, iss 1
International audience; Studying cancer metabolism gives insight into tumorigenic survival mechanisms and susceptibilities. In melanoma, we identify HEXIM1, a transcription elongation regulator, as a melanoma tumor suppressor that responds to nucleot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d2be414500e23e7e55cf569d834dacf
https://hal-pasteur.archives-ouvertes.fr/pasteur-02871949
https://hal-pasteur.archives-ouvertes.fr/pasteur-02871949
Autor:
Abbie Saunders, John E. Brogie, A. Greg Matera, T. K. Rajendra, Brian J. Krueger, John T. Lis, Jason T. Rogers, Stanley C. Sedore, Patricia Uguen, Duy Nguyen, David H. Price
Publikováno v:
Nucleic Acids Research
Regulation of the positive transcription elongation factor, P-TEFb, plays a major role in controlling mammalian transcription and this is accomplished in part by controlled release of P-TEFb from the 7SK snRNP that sequesters the kinase in an inactiv
Publikováno v:
Wiley Interdisciplinary Reviews: RNA. 3:92-103
The human 7SK small nuclear RNA (snRNA) is an abundant noncoding RNA whose function has been conserved in evolution from invertebrates to humans. It is transcribed by RNA polymerase III (RNAPIII) and is located in the nucleus. Together with associate
Autor:
Bret D. Freudenthal, M. Todd Washington, Lokesh Gakhar, John E. Brogie, Christine M. Kondratick
Publikováno v:
Journal of Molecular Biology. 406:9-17
Eukaryotic proliferating cell nuclear antigen (PCNA) is a replication accessory protein that functions in DNA replication, repair, and recombination. The various functions of PCNA are regulated by post-translational modifications including mono-ubiqu