Zobrazeno 1 - 10
of 31
pro vyhledávání: '"John E. Brandt"'
Autor:
John E. Brandt, Sandra K. Prucka, Sandra Gilardi, Lester J. Arnold, Lea C. Harty, Feng Hong, David J. Pulford, Joanne Malia
Publikováno v:
Bioethics
The ease with which genotyping technologies generate tremendous amounts of data on research participants has been well chronicled, a feat that continues to become both faster and cheaper to perform. In parallel to these advances come additional ethic
Publikováno v:
Blood. 96:3414-3421
The marrow repopulating potential (MRP) of different sources of human hematopoietic stem cells (HSCs) was directly compared using an in vivo assay in which severe combined immunodeficient disease (SCID) mice were implanted with human fetal bones. HSC
Publikováno v:
Blood. 96:3414-3421
The marrow repopulating potential (MRP) of different sources of human hematopoietic stem cells (HSCs) was directly compared using an in vivo assay in which severe combined immunodeficient disease (SCID) mice were implanted with human fetal bones. HSC
Autor:
Brian W. Mcguire, Michael S. Gordon, Ronald Hoffman, Jie Tong, C. M. Traycoff, E Bruno, John E. Brandt, Edward F. Srour, Ian K. McNiece
Publikováno v:
STEM CELLS. 11:76-82
The c-kit ligand or stem cell factor (SCF) and the c-kit ligand receptor (KR) are thought to play pivotal roles in the regulation of human hematopoiesis. When added to interleukin 3 (IL-3) and/or granulocyte-macrophage colony stimulating factor (GM-C
Publikováno v:
Blood. 86:502-511
Interactions of hematopoietic progenitor cells (HPC) with bone marrow stroma, mediated by adhesion molecules, are assumed to be critically important to the regulation of hematopoiesis. However, the specific roles of individual adhesion molecules invo
Publikováno v:
Europe PubMed Central
We examined the effects of interleukin-3 (IL-3) and c-kit ligand (KL) on the survival of differentiated hematopoietic progenitor cells (HPC), the burst-forming unit-erythroid (BFU-E); colony-forming unit- granulocyte, erythroid, monocyte, megakaryocy
Autor:
John E. Brandt, Ronald Hoffman, C. M. Traycoff, Tom Leemhuis, Mark Hedrick, Edward F. Srour, Alan W. Flake, Esmail D. Zanjani, Kenneth Cornetta
Publikováno v:
Blood. 82:3333-3342
We have previously reported the ability of uncharacterized human bone marrow (BM) cells to engraft into preimmune fetal sheep, thereby creating sheep-human chimera suitable for in vivo examination of the properties of human hematopoietic stem cells (
Autor:
Ronald Hoffman, Edward F. Srour, Tom Leemhuis, Robert A. Briddell, Susan Grigsby, John E. Brandt
Publikováno v:
Blood. 81:661-669
Although sustained production of committed human hematopoietic progenitor cells in long-term bone marrow cultures (LTBMC) is well documented, evidence for the generation and expansion of human primitive hematopoietic progenitor cells (PHPC) in such c
Autor:
Derigs Hg, Ronald Hoffman, John E. Brandt, S. L. Litz, Boswell Hs, Edward F. Srour, D. A. Morgan
Publikováno v:
Platelets. 6(1)
Terminal megakaryocytic development is characterized by nuclear poly ploidization, appearance of specific granules, and enhanced expression of membrane platelet glycoproteins. We utilized a human GM-CSF-dependent cell line, MB-02, which is capable of
Autor:
E Bruno, Virginia C. Broudy, Ronald Hoffman, Edward F. Srour, John E. Brandt, Robert A. Briddell
Publikováno v:
Blood. 79:3159-3167
A mouse antihuman monoclonal IgG2a antibody, termed stem cell receptor- 1 (SR-1), specific for a determinant of the c-kit ligand receptor (KR), was used as an immunologic probe to analyze KR expression by human bone marrow hematopoietic progenitor ce