Zobrazeno 1 - 7
of 7
pro vyhledávání: '"John E. Battersby"'
Autor:
John E. Battersby, Sharon Ann Baughman, Johannes Kneer, Edward H. Chin, Yvonne S. Lin, Damon I. Papac, Rodney G. Keck, Andrew J. S. Jones
Publikováno v:
Glycobiology. 17:529-540
To understand how the carbohydrate moieties of a recombinant glycoprotein affected its pharmacokinetic (PK) properties, the glycan distribution was directly assessed from serial blood samples taken during PK studies in cynomolgus monkeys and humans.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c41537e4599ba5f9301863f632c93c8
https://doi.org/10.1093/glycob/cwm017
https://doi.org/10.1093/glycob/cwm017
Autor:
Martin Vanderlaan, Kathleen M. Champion, Brad Snedecor, Christina Y. Chen, John E. Battersby, Lavon Riddle
Publikováno v:
Journal of Chromatography A. 927:61-76
An automated dual-column liquid chromatography assay comprised of affinity and reversed-phase separations that quantifies the majority of antibody-related protein species found in crude cell extracts of recombinant origin is described. Although poten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c36cc6f87c5b01895adafc447e431b14
https://doi.org/10.1016/s0021-9673(01)01108-6
https://doi.org/10.1016/s0021-9673(01)01108-6
Autor:
Estela Puchulu-Campanella, William S. Hancock, John E. Battersby, David R. K. Harding, Neill Ward Haggarty, Ross G. Clark, D.J. Poll
Publikováno v:
Journal of Controlled Release. 42:143-156
Dextran T40 was oxidized with periodate to form aldehyde groups to which recombinant human growth hormone (rhGH) was attached. Complex formation involved the reversible formation of an imine conjugate and the extent of complex formation was proportio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0094e63e5b0e626ab124ad2edba3f5c9
https://doi.org/10.1016/0168-3659(96)01370-3
https://doi.org/10.1016/0168-3659(96)01370-3
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 662:335-342
Using capillary HPLC, femtomole amounts of recombinant DNA-derived human growth hormone (rhGH) have been successfully detected from solutions at nanomolar concentrations. The separation used capillaries of 15 cm × 320 μm I.D. and detection was with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::896d9e25416ce7fb76f367164cd62e63
https://doi.org/10.1016/0378-4347(94)00312-2
https://doi.org/10.1016/0378-4347(94)00312-2
Autor:
Christina Y. Chen, Dana C. Andersen, John C. Joly, John E. Battersby, Kathleen M. Champion, Brad Snedecor, Nancy C. Mcfarland, Julie C. Nishihara
Publikováno v:
Biotechnology and bioengineering. 85(5)
During production of a humanized antibody fragment secreted into the periplasm of Escherichia coli, proteolytic degradation of the light chain was observed. In order to determine which protease(s) were responsible for this degradation, we compared ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b2a89649cea6f4eefb23308668ef46b
https://pubmed.ncbi.nlm.nih.gov/14760686
https://pubmed.ncbi.nlm.nih.gov/14760686
Publikováno v:
Journal of chromatography. B, Biomedical sciences and applications. 728(1)
The development of an automated, dual column assay to quantitate and recover the glycoprotein, tumor necrosis factor receptor immunoadhesin (TNFr-IgG) from monkey plasma, human serum, cell culture fluid and buffer samples is described. A combination
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b0fba1f266a2417a6d317ca628a9700
https://pubmed.ncbi.nlm.nih.gov/10379653
https://pubmed.ncbi.nlm.nih.gov/10379653
Autor:
Andrew J.S. Jones, Damon I. Papac, Edward H. Chin, Rodney Keck, Sharon A. Baughman, Yvonne S. Lin, Johannes Kneer, John E. Battersby
Publikováno v:
Glycobiology; May2007, Vol. 17 Issue 5, p529-529, 1p