Zobrazeno 1 - 10
of 40
pro vyhledávání: '"John E Sagartz"'
Autor:
Karoly Toth, Sang R Lee, Baoling Ying, Jacqueline F Spencer, Ann E Tollefson, John E Sagartz, Il-Keun Kong, Zhongde Wang, William S M Wold
Publikováno v:
PLoS Pathogens, Vol 12, Iss 1, p e1005392 (2016)
[This corrects the article DOI: 10.1371/journal.ppat.1005084.].
Externí odkaz:
https://doaj.org/article/7a88433d5c884e0eab016fe4b5b891aa
Autor:
Karoly Toth, Sang R Lee, Baoling Ying, Jacqueline F Spencer, Ann E Tollefson, John E Sagartz, Il-Keun Kong, Zhongde Wang, William S M Wold
Publikováno v:
PLoS Pathogens, Vol 11, Iss 8, p e1005084 (2015)
Human adenoviruses have been studied extensively in cell culture and have been a model for studies in molecular, cellular, and medical biology. However, much less is known about adenovirus replication and pathogenesis in vivo in a permissive host bec
Externí odkaz:
https://doaj.org/article/d6ff951ccb074add9e444fdee9313ac4
Autor:
Daniel Stone, Kelly R. Long, Michelle A. Loprieno, Harshana S. De Silva Feelixge, Elizabeth J. Kenkel, R. Matt Liley, Stephen Rapp, Pavitra Roychoudhury, Thuy Nguyen, Laurence Stensland, Rossana Colón-Thillet, Lindsay M. Klouser, Nicholas D. Weber, Connie Le, Jessica Wagoner, Erin A. Goecker, Alvason Zhenhua Li, Karsten Eichholz, Lawrence Corey, D. Lorne Tyrrell, Alexander L. Greninger, Meei-Li Huang, Stephen J. Polyak, Martine Aubert, John E. Sagartz, Keith R. Jerome
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 20, Iss , Pp 258-275 (2021)
Chronic hepatitis B virus (HBV) infection is a major public health problem. New treatment approaches are needed because current treatments do not target covalently closed circular DNA (cccDNA), the template for HBV replication, and rarely clear the v
Externí odkaz:
https://doaj.org/article/50136f1751074d8594ac5811c80e88ea
Autor:
Karoly Toth, Baoling Ying, Ann E. Tollefson, Jacqueline F. Spencer, Lata Balakrishnan, John E. Sagartz, Robert Mark L. Buller, William S. M. Wold
Publikováno v:
Viruses, Vol 7, Iss 3, Pp 1409-1428 (2015)
Adenovirus infections of immunocompromised pediatric hematopoietic stem cell transplant patients can develop into serious and often deadly multi-organ disease. There are no drugs approved for adenovirus infections. Cidofovir (an analog of 2-deoxycyti
Externí odkaz:
https://doaj.org/article/50ff05ddc4ce4937b99930b25d086754
Autor:
Jessica Wagoner, Elizabeth J. Kenkel, Daniel Stone, Nicholas D. Weber, R. Matt Liley, Lindsay M. Klouser, Martine Aubert, Stephen J. Polyak, Keith R. Jerome, Connie Le, John E. Sagartz, Pavitra Roychoudhury, Stephen R. Rapp, Lawrence Corey, Erin A. Goecker, Rossana Colón-Thillet, Thuy Nguyen, Kelly R. Long, Michelle A. Loprieno, D. Lorne Tyrrell, Alexander L. Greninger, Laurence Stensland, Meei-Li Huang, Harshana S. De Silva Feelixge, Karsten Eichholz, Alvason Zhenhua Li
Publikováno v:
Molecular Therapy. Methods & Clinical Development
Molecular Therapy: Methods & Clinical Development, Vol 20, Iss, Pp 258-275 (2021)
Molecular Therapy: Methods & Clinical Development, Vol 20, Iss, Pp 258-275 (2021)
Chronic hepatitis B virus (HBV) infection is a major public health problem. New treatment approaches are needed because current treatments do not target covalently closed circular DNA (cccDNA), the template for HBV replication, and rarely clear the v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f34c3eeb31ffde7f259c3c7a01b086e
http://europepmc.org/articles/PMC7803634
http://europepmc.org/articles/PMC7803634
Autor:
Lata Balakrishnan, Karoly Toth, Ann E. Tollefson, R. M. L. Buller, Jacqueline F. Spencer, William S. M. Wold, John E. Sagartz, Baoling Ying
Publikováno v:
Viruses
Volume 7
Issue 3
Pages 1409-1428
Viruses, Vol 7, Iss 3, Pp 1409-1428 (2015)
Volume 7
Issue 3
Pages 1409-1428
Viruses, Vol 7, Iss 3, Pp 1409-1428 (2015)
Adenovirus infections of immunocompromised pediatric hematopoietic stem cell transplant patients can develop into serious and often deadly multi-organ disease. There are no drugs approved for adenovirus infections. Cidofovir (an analog of 2-deoxycyti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::456481d7d4dc9c71147f55bdfab4df50
https://doi.org/10.3390/v7031409
https://doi.org/10.3390/v7031409
Publikováno v:
The Journal of Immunology. 194:1806-1818
Vaccines against mucosally invasive, intracellular pathogens must induce a myriad of immune responses to provide optimal mucosal and systemic protection, including CD4+ T cells, CD8+ T cells, and Ab-producing B cells. In general, CD4+ T cells are kno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17ddca9df5829c1de64197acd4f4d19c
https://doi.org/10.4049/jimmunol.1303163
https://doi.org/10.4049/jimmunol.1303163
Autor:
R. Mark L. Buller, Nathan L. Ponzar, Juan A. Villa, Lisa Wilson, R. Matt Liley, John E. Sagartz, Elena Lomonosova, Ryan P. Murelli, Kelly R. Long, John E. Tavis, John Bial, Qilan Li, Alexandre Grigoryan, Stephen R. Rapp, Erin Touchette
Chronic hepatitis B virus infection cannot be cured by current therapies, so new treatments are urgently needed. We recently identified novel inhibitors of the hepatitis B virus ribonuclease H that suppress viral replication in cell culture. Here, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b46be5b091682b241b92f80dc87b2c5
https://europepmc.org/articles/PMC5743599/
https://europepmc.org/articles/PMC5743599/
Autor:
John E. Sagartz, Jacqueline F. Spencer, William S. M. Wold, Baoling Ying, Ann E. Tollefson, Karoly Toth
Publikováno v:
Journal of Virology. 91
Syrian hamsters are permissive for the replication of species C human adenoviruses (HAdV-C). The virus replicates to high titers in the liver of these animals after intravenous infection, while respiratory infection results in virus replication in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a721cb8ba50f042ad2cba28df5e78ae6
https://doi.org/10.1128/jvi.00284-17
https://doi.org/10.1128/jvi.00284-17
Autor:
Thanh-Long M. Nguyen, Clifford J. Bellone, Russell A. Kesman, John E. Sagartz, Shradha S. Khurana, Benjamin J. Capoccia, Jason C. Mills, Richard J. DiPaolo
Publikováno v:
Cancer Research. 73:2117-2126
Chronic inflammation is a major risk factor for cancer, including gastric cancers and other gastrointestinal cancers. For example, chronic inflammation caused by autoimmune gastritis (AIG) is associated with an increased risk of gastric polyps, gastr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1076d64404a0da2b23243c2ddea6577f
https://doi.org/10.1158/0008-5472.can-12-3957
https://doi.org/10.1158/0008-5472.can-12-3957