Výsledky vyhledávání - "John E Moran"

Fourteen-Day Evolution of COVID-19 Symptoms during the Third Wave in Nonvaccinated Subjects and Effects of Hesperidin Therapy: A Randomized, Double-Blinded, Placebo-Controlled Study

Autor: Jocelyn Dupuis, Pierre Laurin, Jean-Claude Tardif, Leslie Hausermann, Camille Rosa, Marie-Claude Guertin, Karen Thibaudeau, Lyne Gagnon, Frank Cesari, Martin Robitaille, John E. Moran

Publikováno v: Evidence-Based Complementary and Alternative Medicine. 2022:1-10

COVID-19 symptoms can cause substantial disability, yet no therapy can currently reduce their frequency or duration. We conducted a double-blind placebo-controlled trial of hesperidin 1000 mg once daily for 14 days in 216 symptomatic nonvaccinated CO

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::282b131042ecab7307c99c36053f5733
https://doi.org/10.1155/2022/3125662

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Patterns of altered neural synchrony in the default mode network in autism spectrum disorder revealed with magnetoencephalography (MEG): Relationship to clinical symptomatology

Autor: Maggie Ugolini, Jeremy J. Albright, Kenneth W. Rusiniak, Annette E. Richard, Ana Mercedes Flores, Ioulia Kovelman, Kaitlyn McFarlane, Neelima Wagley, John E. Moran, Ryan Goodcase, Jonathan Brennan, Susan M. Bowyer, Renee Lajiness-O'Neill, Casey Swick, Tiffany Andersen

Publikováno v: Autism Research. 11:434-449

Disrupted neural synchrony may be a primary electrophysiological abnormality in autism spectrum disorders (ASD), altering communication between discrete brain regions and contributing to abnormalities in patterns of connectivity within identified neu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::926b11e5aa934ce7ae141f01d9266fb4
https://doi.org/10.1002/aur.1908

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Phase 2 clinical trial of PBI-4050 in patients with idiopathic pulmonary fibrosis

Autor: John E. Moran, Gary R. Albert, Lyne Gagnon, Nasreen Khalil, Martin Kolb, Frank Cesari, Joseph M. Parker, Christopher J. Ryerson, Renata Sawtell, Paul Hernandez, Aline Hagerimana, Pierre Laurin, Eric Turcotte, Shane Shapera, Hélène Manganas, André M. Cantin

Publikováno v: The European Respiratory Journal

PBI-4050 is a novel orally active small-molecule compound with demonstrated anti-fibrotic activity in several models of fibrosis, including lung fibrosis. We present results from our first clinical study of PBI-4050 in patients with idiopathic pulmon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::410340e43330324b8fe13d84beff9849
http://europepmc.org/articles/PMC6422836

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Potential Biomarkers of Schizophrenia from MEG Resting-State Functional Connectivity Networks: Preliminary Data

Autor: Norman Tepley, Lawrence Kim, Valentina Gumenyuk, Susan M. Bowyer, Klevest Gjini, Syeda U. Rizvi, Nash N. Boutros, John E. Moran, Xiao Zhu

Publikováno v: Journal of Behavioral and Brain Science. :1-11

Previous studies examining coherence and connectivity deviations in schizophrenia patients relied on standard coherence measures between recording sites (at the sensor level). A coherence source imaging (CSI) methodology where coherence is assessed w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4b08ec5e4a4e679a40ea867ea2980c29
https://doi.org/10.4236/jbbs.2015.51001

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Plasminogen replacement therapy for the treatment of children and adults with congenital plasminogen deficiency

Autor: Gary R. Albert, Joseph M. Parker, John E. Moran, Brandon M. Hardesty, Pierre Laurin, Neelam Thukral, Per Morten Sandset, Charles Nakar, Karen Thibaudeau, Amy D. Shapiro

Publikováno v: Blood. 131(12)

Congenital plasminogen deficiency is caused by mutations in PLG, the gene coding for production of the zymogen plasminogen, and is an ultrarare disorder associated with abnormal accumulation or growth of fibrin-rich pseudomembranous lesions on mucous

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cec892cf0c83322b7d97ac76a9d032d
https://pubmed.ncbi.nlm.nih.gov/29567753

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Patterns of altered neural synchrony in the default mode network in autism spectrum disorder revealed with magnetoencephalography (MEG): Relationship to clinical symptomatology

Autor: Renée, Lajiness-O'Neill, Jonathan R, Brennan, John E, Moran, Annette E, Richard, Ana-Mercedes, Flores, Casey, Swick, Ryan, Goodcase, Tiffany, Andersen, Kaitlyn, McFarlane, Kenneth, Rusiniak, Ioulia, Kovelman, Neelima, Wagley, Maggie, Ugolini, Jeremy, Albright, Susan M, Bowyer

Publikováno v: Autism research : official journal of the International Society for Autism Research. 11(3)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::db19ec3bbc4cd7c7e2966c90be945d01
https://pubmed.ncbi.nlm.nih.gov/29251830

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Neurophysiological findings from magnetoencephalography in autism spectrum disorder: a comprehensive review

Autor: Annette E. Richard, Renee Lajiness-O'Neill, John E. Moran, Nash N. Boutros, Andrew Zillgitt, Susan M. Bowyer

Publikováno v: Future Neurology. 9:355-384

ABSTRACT: Autism spectrum disorder (ASD) is an etiologically and clinically heterogeneous group of neurodevelopmental disorders, diagnosed exclusively by the behavioral phenotype. The neural basis of altered social, communicative, somatosensory, and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f82dbbfb3b8a12a1a2909bfdfaf51e8c
https://doi.org/10.2217/fnl.14.24

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Magnetoencephalography Coherence Source Imaging in Dyslexia: Activation of Working Memory Pathways

Autor: Daniel Jacobson, Amy K. Olszewski, Renee Lajiness-O'Neill, Kelly Vogt, Aimee M. Moore, Laszlo A. Erdodi, Lesley Pawluk, Susan M. Bowyer, John E. Moran, Alfred Mansour, Annette E. Richard

Publikováno v: Psychology. :1879-1910

This study investigates the functional connectivity of neuronal networks critical for working memory in individuals with dyslexia by means of magnetoenchephalographic (MEG) coherence imaging. Individuals with dyslexia showed an early onset of activat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0ec7e059732d5713c6d2cae0d530cfbf
https://doi.org/10.4236/psych.2014.516193

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Periodic Discharges: Insight From Magnetoencephalography

Autor: Norman Tepley, Susan M. Bowyer, Karen M. Mason, John E. Moran, Vladimir Shvarts, Gabor Zoltay, Andrew Zillgitt, David E. Burdette

Publikováno v: Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society. 34(3)

PURPOSE This study used magnetoencephalography (MEG) dipole localization and coherence measurement to evaluate the magnetic fields associated with periodic discharges. The primary goal of the study was to evaluate whether MEG could consistently local

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ec83fc1de8fc3ffef77722aa545265b
https://pubmed.ncbi.nlm.nih.gov/27832046

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Application of DTI connectivity in lateralization of mTLE

Autor: Mohammad R. Nazem-Zadeh, Esmaeil Davoodi-Bojd, Fariborz Mahmoudi, Susan M. Bowyer, John E. Moran, Hassan Bagher-Ebadian, Andrew Zillgitt, Kost Elisevich, Hamid Soltanian-Zadeh

Publikováno v: EMBC

Diffusion tensor imaging (DTI) is a noninvasive imaging method for measuring the diffusion properties of the underlying white matter tracts through which epileptiform activity is propagated. This study investigates the structural abnormalities quanti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e09e82f788361ec88040216a56720dc
https://doi.org/10.1109/embc.2016.7591978

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