Zobrazeno 1 - 10
of 47
pro vyhledávání: '"John E M Midgley"'
Publikováno v:
Drugs in Context, Vol 8, Pp 1-18 (2019)
Levothyroxine (LT4) therapy has a long history, a well-defined pharmacological profile and a favourable safety record in the alleviation of hypothyroidism. However, questions remain in defining the threshold for the requirement of treatment in patien
Externí odkaz:
https://doaj.org/article/7a37aa97e1a04b3d83a5cac22483a1c3
Publikováno v:
Frontiers in Endocrinology, Vol 7 (2016)
Thyroid hormone concentrations only become sufficient to maintain a euthyroid state through appropriate stimulation by pituitary TSH. In such a dynamic system under constant high pressure, guarding against overstimulation becomes vital. Therefore, se
Externí odkaz:
https://doaj.org/article/4754e0423d6947e4854099f98ec9080b
Publikováno v:
Therapeutic Advances in Endocrinology and Metabolism, Vol 14 (2023)
Background: Thyroid hormones are controlled by the hypothalamic–pituitary–thyroid (HPT) axis through a complex network of regulatory loops, involving the hormones TRH, TSH, FT4, and FT3. The relationship between TSH and FT4 is widely used for dia
Externí odkaz:
https://doaj.org/article/944d026a2fab4c45b525bb41f59166b0
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Endocrine regulation in the hypothalamic-pituitary-thyroid (HPT) axis is orchestrated by physiological circuits which integrate multiple internal and external influences. Essentially, it provides either of the two responses to overt biological challe
Externí odkaz:
https://doaj.org/article/a6382158f0cf4200a150a2f0d15ee32c
Publikováno v:
Frontiers in Endocrinology, Vol 8 (2017)
In thyroid health, the pituitary hormone thyroid-stimulating hormone (TSH) raises glandular thyroid hormone production to a physiological level and enhances formation and conversion of T4 to the biologically more active T3. Overstimulation is limited
Externí odkaz:
https://doaj.org/article/fba70484ecea4f66a7a5541fd800e9f2
Publikováno v:
Frontiers in endocrinology. 13
Endocrine regulation in the hypothalamic-pituitary-thyroid (HPT) axis is orchestrated by physiological circuits which integrate multiple internal and external influences. Essentially, it provides either of the two responses to overt biological challe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74f5159918b9d1ecb7544438a2d3ac29
https://pubmed.ncbi.nlm.nih.gov/35757421
https://pubmed.ncbi.nlm.nih.gov/35757421
Publikováno v:
European Journal of Endocrinology. 183:L1-L3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43f3fa6af93a864e259b82c7175039d9
https://doi.org/10.1530/eje-20-0134
https://doi.org/10.1530/eje-20-0134
Publikováno v:
Clinical Pharmacokinetics. 59:655-657
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4248d3437d7398905643467707500f80
https://doi.org/10.1007/s40262-020-00887-x
https://doi.org/10.1007/s40262-020-00887-x
Publikováno v:
Drugs in Context, Vol 8, Pp 1-18 (2019)
Drugs in Context
Drugs in Context
Levothyroxine (LT4) therapy has a long history, a well-defined pharmacological profile and a favourable safety record in the alleviation of hypothyroidism. However, questions remain in defining the threshold for the requirement of treatment in patien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7407a855df9cfbd4e8f900d4fd01c40
https://www.drugsincontext.com/individualised-requirements-for-optimum-treatment-of-hypothyroidism:-complex-needs,-limited-options/
https://www.drugsincontext.com/individualised-requirements-for-optimum-treatment-of-hypothyroidism:-complex-needs,-limited-options/
Publikováno v:
European Journal of Endocrinology. 185:L5-L6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce766f3ce70b026a95b3db10ef61986b
https://doi.org/10.1530/eje-20-1405
https://doi.org/10.1530/eje-20-1405