Zobrazeno 1 - 10
of 525
pro vyhledávání: '"John E Harris"'
Publikováno v:
JAAD Case Reports, Vol 49, Iss , Pp 65-67 (2024)
Externí odkaz:
https://doaj.org/article/6e2dd6a84b104ae98ffc19dd5538cd22
Autor:
Thierry Passeron, Khaled Ezzedine, Iltefat Hamzavi, Nanja van Geel, Bethanee J. Schlosser, Xiaoqiang Wu, Xiaohong Huang, Ahmed M. Soliman, David Rosmarin, John E. Harris, Heidi S. Camp, Amit G. Pandya
Publikováno v:
EClinicalMedicine, Vol 73, Iss , Pp 102655- (2024)
Summary: Background: Janus kinase (JAK) inhibition is a promising approach for treating vitiligo. We aimed to assess the efficacy and safety of upadacitinib, an oral selective JAK inhibitor, in adults with non-segmental vitiligo. Methods: This was a
Externí odkaz:
https://doaj.org/article/9da9413afcff468688e2a1b4240ef6c2
Autor:
Nicole Trepanowski, MD, Rebecca M. Yim, BA, Rachel Wetstone, MPH, Elizabeth MacDonald, BS, Sarah Servattalab, MD, Subin Jacob-George, PA, John E. Harris, MD, PhD
Publikováno v:
JAAD Case Reports, Vol 42, Iss , Pp 26-30 (2023)
Externí odkaz:
https://doaj.org/article/970c59f6f05341b483ee08942368a88c
Autor:
Qi Tang, Hassan H. Fakih, Mohammad Zain UI Abideen, Samuel R. Hildebrand, Khashayar Afshari, Katherine Y. Gross, Jacquelyn Sousa, Allison S. Maebius, Christina Bartholdy, Pia Pernille Søgaard, Malene Jackerott, Vignesh Hariharan, Ashley Summers, Xueli Fan, Ken Okamura, Kathryn R. Monopoli, David A. Cooper, Dimas Echeverria, Brianna Bramato, Nicholas McHugh, Raymond C. Furgal, Karen Dresser, Sarah J. Winter, Annabelle Biscans, Jane Chuprin, Nazgol-Sadat Haddadi, Shany Sherman, Ümmügülsüm Yıldız-Altay, Mehdi Rashighi, Jillian M. Richmond, Claire Bouix-Peter, Carine Blanchard, Adam Clauss, Julia F. Alterman, Anastasia Khvorova, John E. Harris
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Inhibition of Janus kinase (JAK) family enzymes is a popular strategy for treating inflammatory and autoimmune skin diseases. In the clinic, small molecule JAK inhibitors show distinct efficacy and safety profiles, likely reflecting variable
Externí odkaz:
https://doaj.org/article/4a8cb6635b9d4fb98e9074b6bcb3b50f
Autor:
Qi Tang, Katherine Y. Gross, Hassan H. Fakih, Samuel O. Jackson, Mohammad Zain U.I. Abideen, Kathryn R. Monopoli, Carine Blanchard, Claire Bouix-Peter, Thibaud Portal, John E. Harris, Anastasia Khvorova, Julia F. Alterman
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 35, Iss 1, Pp 102117- (2024)
Identifying therapeutic oligonucleotides that are cross-reactive to experimental animal species can dramatically accelerate the process of preclinical development and clinical translation. Here, we identify fully chemically-modified small interfering
Externí odkaz:
https://doaj.org/article/20b9e2482d6e42e2ba4c20b806a408b4
Autor:
Michael D. Howell, Fiona I. Kuo, Beth Rumberger, Erika Boarder, Kang Sun, Kathleen Butler, John E. Harris, Pearl Grimes, David Rosmarin
Publikováno v:
JID Innovations, Vol 3, Iss 6, Pp 100230- (2023)
Background: Efficacy of ruxolitinib cream, a topical Jak1/Jak2 inhibitor, was demonstrated in a phase 2 trial in patients with vitiligo. Objective: This study aimed to characterize circulating inflammatory biomarker profiles in patients who demonstra
Externí odkaz:
https://doaj.org/article/a9d77786420842d382dae991fba53ce0
Autor:
Rhea Singh, BS, Jay L. Cohen, MD, Michael Astudillo, MD, John E. Harris, MD, PhD, Esther E. Freeman, MD, PhD
Publikováno v:
JAAD Case Reports, Vol 28, Iss , Pp 142-144 (2022)
Externí odkaz:
https://doaj.org/article/0f43d5a59f0543bba23c548fae5e7e23
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