Zobrazeno 1 - 10
of 212
pro vyhledávání: '"John E Edwards"'
Autor:
Shakti Singh, Priya Uppuluri, Zeinab Mamouei, Abdullah Alqarihi, Hana Elhassan, Samuel French, Shawn R Lockhart, Tom Chiller, John E Edwards, Ashraf S Ibrahim
Publikováno v:
PLoS Pathogens, Vol 15, Iss 8, p e1007460 (2019)
Candida auris is an emerging, multi-drug resistant, health care-associated fungal pathogen. Its predominant prevalence in hospitals and nursing homes indicates its ability to adhere to and colonize the skin, or persist in an environment outside the h
Externí odkaz:
https://doaj.org/article/591776a7f04541d49e6e74af7b86336e
Autor:
Priya Uppuluri, Lin Lin, Abdullah Alqarihi, Guanpingsheng Luo, Eman G Youssef, Sondus Alkhazraji, Nannette Y Yount, Belal A Ibrahim, Michael Anthony Bolaris, John E Edwards, Marc Swidergall, Scott G Filler, Michael R Yeaman, Ashraf S Ibrahim
Publikováno v:
PLoS Pathogens, Vol 14, Iss 5, p e1007056 (2018)
Different pathogens share similar medical settings and rely on similar virulence strategies to cause infections. We have previously applied 3-D computational modeling and bioinformatics to discover novel antigens that target more than one human patho
Externí odkaz:
https://doaj.org/article/100150df04e849208bce94ce12f9ddd6
Autor:
Mingfu Liu, Lin Lin, Teclegiorgis Gebremariam, Guanpingsheng Luo, Christopher D Skory, Samuel W French, Tsui-Fen Chou, John E Edwards, Ashraf S Ibrahim
Publikováno v:
PLoS Pathogens, Vol 11, Iss 5, p e1004842 (2015)
Dialysis patients with chronic renal failure receiving deferoxamine for treating iron overload are uniquely predisposed for mucormycosis, which is most often caused by Rhizopus oryzae. Although the deferoxamine siderophore is not secreted by Mucorale
Externí odkaz:
https://doaj.org/article/e4e60f85d2dc44689751f9751f79818b
Autor:
Michael R Yeaman, Scott G Filler, Clint S Schmidt, Ashraf S Ibrahim, John E Edwards, John P Hennessey
Publikováno v:
Frontiers in Immunology, Vol 5 (2014)
Recent perspectives forecast a new paradigm for future 3rd generation vaccines based on commonalities found in diverse pathogens or convergent immune defenses to such pathogens. For Staphylococcus aureus, recurring infections and a limited success of
Externí odkaz:
https://doaj.org/article/45313c3786db43d9a2a95c56d1a2d88c
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e25909 (2011)
We previously reported that Candida albicans cell surface protein Hyr1 encodes a phagocyte killing resistance factor and active vaccination with a recombinant N-terminus of Hyr1 protein (rHyr1p-N), significantly protects immunocompetent mice from dis
Externí odkaz:
https://doaj.org/article/3c53ec7d8e7f4063930a62b4f2681f38
Autor:
Lin Lin, Ashraf S Ibrahim, Xin Xu, Joshua M Farber, Valentina Avanesian, Beverlie Baquir, Yue Fu, Samuel W French, John E Edwards, Brad Spellberg
Publikováno v:
PLoS Pathogens, Vol 5, Iss 12, p e1000703 (2009)
We sought to define protective mechanisms of immunity to Staphylococcus aureus and Candida albicans bloodstream infections in mice immunized with the recombinant N-terminus of Als3p (rAls3p-N) vaccine plus aluminum hydroxide (Al(OH(3)) adjuvant, or a
Externí odkaz:
https://doaj.org/article/89fb79374282438c9e1b522d5ea4e210
Autor:
Ricardo S Almeida, Sascha Brunke, Antje Albrecht, Sascha Thewes, Michael Laue, John E Edwards, Scott G Filler, Bernhard Hube
Publikováno v:
PLoS Pathogens, Vol 4, Iss 11, p e1000217 (2008)
Iron sequestration by host iron-binding proteins is an important mechanism of resistance to microbial infections. Inside oral epithelial cells, iron is stored within ferritin, and is therefore not usually accessible to pathogenic microbes. We observe
Externí odkaz:
https://doaj.org/article/9bd70ceb7671409aa6e079e2f114f912
Autor:
Quynh T Phan, Carter L Myers, Yue Fu, Donald C Sheppard, Michael R Yeaman, William H Welch, Ashraf S Ibrahim, John E Edwards, Scott G Filler
Publikováno v:
PLoS Biology, Vol 5, Iss 3, p e64 (2007)
Candida albicans is the most common cause of hematogenously disseminated and oropharyngeal candidiasis. Both of these diseases are characterized by fungal invasion of host cells. Previously, we have found that C. albicans hyphae invade endothelial ce
Externí odkaz:
https://doaj.org/article/7de12b1cc3b141c5b28ce0aacaecaed3
Autor:
Clarissa J Nobile, David R Andes, Jeniel E Nett, Frank J Smith, Fu Yue, Quynh-Trang Phan, John E Edwards, Scott G Filler, Aaron P Mitchell
Publikováno v:
PLoS Pathogens, Vol 2, Iss 7, p e63 (2006)
The fungal pathogen Candida albicans is frequently associated with catheter-based infections because of its ability to form resilient biofilms. Prior studies have shown that the transcription factor Bcr1 governs biofilm formation in an in vitro cathe
Externí odkaz:
https://doaj.org/article/6e469df78c6a4089b3f6363e24ac266e
A compendium of research in the field of medical mycology. Serves as a valuable resource for students, fellows, instructors, researchers, specialists, clinicians, and anyone interested in the general field of microbial pathogenesis.
