Zobrazeno 1 - 10
of 177
pro vyhledávání: '"John E Donelson"'
Publikováno v:
PLoS Pathogens, Vol 3, Iss 10, Pp 1432-1445 (2007)
The Trypanosoma brucei genome encodes three groups of zinc metalloproteases, each of which contains approximately 30% amino acid identity with the major surface protease (MSP, also called GP63) of Leishmania. One of these proteases, TbMSP-B, is encod
Externí odkaz:
https://doaj.org/article/f49aa3fe562e48ac9f09481b03129f88
Autor:
Gloria R. Monteiro, V. Macedo-Silva, Jenefer M. Blackwell, John E. Donelson, Selma M B Jeronimo, Diego Gomes Teixeira, M.A. Kurtz, Paulo Ricardo Porfírio do Nascimento, Alistair Miles, Mary E. Wilson, A. Kitchen, Richard D. Pearson, João Paulo Matos Santos Lima, Maria Zélia Fernandes, M. Ansaldi, Daniella Regina Arantes Martins, Judy A. Streit, Maria de Fátima Freire de Melo Ximenes
Publikováno v:
International Journal for Parasitology. 47:655-665
The genomic sequences of 20 Leishmania infantum isolates collected in northeastern Brazil were compared with each other and with the available genomic sequences of 29 L. infantum/donovani isolates from Nepal and Turkey. The Brazilian isolates were ob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0721d0d7bb8917cca13aee91f2103e38
https://doi.org/10.1016/j.ijpara.2017.04.004
https://doi.org/10.1016/j.ijpara.2017.04.004
Autor:
David W. Johnson, Barclay G. Barrell, Sharon Moule, Luke J. Tallon, Ian Goodhead, Lihua Hou, Jeremy Peterson, Danielle Walker, David M. A. Martin, Sara E. Melville, Kristine Jones, Martin Aslett, Appolinaire Djikeng, Neil Hall, Inna Cherevach, Hean Koo, Ester Rabbinowitsch, Steven L. Salzberg, Sarah Sharp, Mark Raymond Adams, Claire Arrowsmith, Andrew Barron, Elisabetta Ullu, Rebecca Atkin, Mark Simmonds, Al Ivens, John E. Donelson, Elodie Ghedin, P. Mooney, Adrian Tivey, Tamara Feldblyum, Audrey Fraser, Natasha Larke, Keith Gull, Jonathon Doggett, Doug Ormond, Jennifer R. Wortman, Claire M. Fraser, Carol Churcher, Mark Carrington, Chris P Reitter, Anjana J. Simpson, Joshua Shallom, Louise Clark, Brian J. Haas, Arnaud Kerhornou, Andrew Tait, Matthew Berriman, Mandy Sanders, Halina Norbertczak, Justin Johnson, Sally Whitehead, Jessica B. Hostetler, Scott M. Landfear, Frédéric Bringaud, Barbara Harris, Ann Cronin, J. David Barry, Fred R. Opperdoes, U. Cecilia M. Alsmark, Brian White, Craig Corton, John Woodward, Najib M. El-Sayed, Alexandra Line, Elisabet Caler, Annette MacLeod, Heidi Hauser, T. Martin Embley, Marie-Adèle Rajandream, Daniella Castanheira Bartholomeu, Mark C. Field, Angela Lord, Linda Hannick, C. Michael R. Turner, Gareth W. Morgan, Hubert Renauld, Bill Wickstead, Christiane Hertz-Fowler, Gaëlle Blandin, Shiliang Wang, Christopher S. Peacock, Tracey-Jane Chillingworth, Michael A. Quail, Karen Mungall, Robert L. Davies, Vanessa Leech, Alan H. Fairlamb, Susan Van Aken, Nicola Lennard, N. Hamlin, Ulrike Böhme, Karen Brooks, Owen White, Christopher Larkin, Lucio Marcello, Zahra Hance, David Harper, David Wanless, Grace Pai, Kay Jagels, Seth Schobel
African trypanosomes cause human sleeping sickness and livestock trypanosomiasis in sub-Saharan Africa. We present the sequence and analysis of the 11 megabase-sized chromosomes of Trypanosoma brucei . The 26-megabase genome contains 9068 predicted g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3750ef339c57c8ea7b18444005230de3
https://ora.ox.ac.uk/objects/uuid:68a73f00-8613-4389-bf92-d156df3b8386
https://ora.ox.ac.uk/objects/uuid:68a73f00-8613-4389-bf92-d156df3b8386
Autor:
Bianca Loveless, John E. Donelson, Terry W. Pearson, Christiane Hertz-Fowler, Noboru Inoue, Tatsuya Sakurai, Brett A. Eyford, Derek Smith
Publikováno v:
Molecular and Biochemical Parasitology
Graphical abstract Highlights ► All 4 major life cycle stages of Trypanosoma congolense were grown in the lab. ► Relative protein expression among the life cycle stages was studied by iTRAQ MS. ► Several known expression trends were observed an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b329f5d7762c32c3fb496aaf8fa9e912
Leishmania infantum chagasi: A genome-based approach to identification of excreted/secreted proteins
Autor:
Selma M. B. Jeronimo, Mary E. Wilson, John E. Donelson, Norikiyo Ueno, Alexandra B. Keenan, Sruti DebRoy
Publikováno v:
Experimental Parasitology. 126:582-591
The parasitic protozoan, Leishmania, survives in harsh environments within its mammalian and sand fly hosts. Secreted proteins likely play critical roles in the parasite’s interactions with its environment. As a preliminary identification of the sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e043aa1d0121d09b873aed89d83d009e
https://doi.org/10.1016/j.exppara.2010.06.011
https://doi.org/10.1016/j.exppara.2010.06.011
Publikováno v:
Molecular and Biochemical Parasitology. 159:134-137
Most trypanosomatid genes are transcribed into polycistronic precursor RNAs that are processed into monocistronic mRNAs possessing a 39-nucleotide spliced leader (SL) at their 5'-ends and polyadenylation at their 3'-ends. We show here that precursor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e24c1afb92289d498c031d80ad454e31
https://doi.org/10.1016/j.molbiopara.2008.02.006
https://doi.org/10.1016/j.molbiopara.2008.02.006
The major surface protease (MSP or GP63) in the intracellular amastigote stage of Leishmania chagasi
Publikováno v:
Molecular and Biochemical Parasitology. 157:148-159
The Leishmania spp. protozoa have an abundant surface metalloprotease called MSP (major surface protease), which in Leishmania chagasi is encoded by three distinct gene classes (MSPS, MSPL, MSPC). Although MSP has been characterized primarily in extr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcd86702ac66ea2738113f1c3e213714
https://doi.org/10.1016/j.molbiopara.2007.10.008
https://doi.org/10.1016/j.molbiopara.2007.10.008
Publikováno v:
Experimental Parasitology. 118:129-133
Homogenous metacyclic promastigotes of Leishmania chagasi were isolated by buoyant density from in vitro heterogeneous cultures and used for biochemical characterization of isoforms of the major surface protease (MSP). Compared to stationary phase pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efa46a823bf39b0e9d9cf7df117b4d59
https://doi.org/10.1016/j.exppara.2007.06.012
https://doi.org/10.1016/j.exppara.2007.06.012
Publikováno v:
Experimental Parasitology. 110:102-107
The intercoding regions of many Leishmania sp. genes have been implicated in the regulation of mRNA processing, stability, and translation. Herein we show that the intercoding region of the Leishmania chagasi alpha-tubulin gene (alpha-TUB) confers st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a68a97c0934ef6d6356784d56ac8b374
https://doi.org/10.1016/j.exppara.2005.02.008
https://doi.org/10.1016/j.exppara.2005.02.008