Zobrazeno 1 - 10
of 18
pro vyhledávání: '"John E Dillberger"'
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 37, Iss 2, Pp 510-517 (2023)
Abstract Background Delayed postoperative hemorrhage (DEPOH) is an important health concern for Scottish deerhounds. Hypothesis/Objectives Identify genes associated with DEPOH in Scottish deerhounds. Animals Two hundred sixty‐nine privately owned S
Externí odkaz:
https://doaj.org/article/4c30c5fb515844728afe82d2f338fe3e
Publikováno v:
Veterinary Record Case Reports. 11
Autor:
John E Dillberger, Thomas D Roper, Allison J. Armstrong, Brian R. Wamhoff, Stephen A. Hoang, Matthew W. Olson, Justin M. Taylor, Brad R. Henke, John E. Reardon, Maria Sol Collado, Brian A. Johns, Robert A. Figler, Taylor D. Pourtaheri
Publikováno v:
Journal of medicinal chemistry. 64(8)
Propionic acidemia (PA) and methylmalonic acidemia (MMA) are rare autosomal recessive disorders of propionyl-CoA (P-CoA) catabolism, caused by a deficiency in the enzymes P-CoA carboxylase and methylmalonyl-CoA (M-CoA) mutase, respectively. PA and MM
Publikováno v:
Toxicologic Pathology. 47:93-96
It is important to detect injection site reactions during the nonclinical phases of drug development. However, differentiating between normal changes following needle trauma and changes due to the toxicity of injected drugs can be challenging. Theref
Autor:
John E. Dillberger, Shambhunath Choudhary, Ricardo Ochoa, Rick Adler, Tanasa Osborne, Kevin McDorman
Publikováno v:
Toxicologic Pathology. 45:1012-1021
In the constantly evolving field of toxicologic pathology, a pathologist’s career is often characterized by multiple career transitions. However, these transitions can be challenging and/or overwhelming and may require a shift in focus, strategic a
Autor:
Ursula Rehkemper, David Sokal, John E. Dillberger, Thomas Smith, R. Michael McClain, Aida M. Cancel
Publikováno v:
International Journal of Toxicology. 25:109-118
Quinacrine is an acridine derivative under investigation for its use in nonsurgical female sterilization. Safety issues regarding the carcinogenic potential of quinacrine have been raised because it is mutagenic and clastogenic in vitro. The objectiv
Autor:
Byron Ellis, Debra Weigl, Jeff T. Hutchins, Mark de Serres, Randolph B. DePrince, John E. Dillberger, Sharon K. Rudolph, Christine M. Boytos
Publikováno v:
STEM CELLS. 17:203-209
Administration of exogenous proteins and peptides as therapeutics carries with it the potential for immune system recognition and the development of neutralizing antibodies to endogenous regulatory proteins. PEGylation of proteins typically reduces t
Autor:
William E Heydorn, Gail H. Hurst, Neil M. Sussman, Bruce Lippert, John T. Yarrington, Ronald J. Marler, John P. Gibson, John E. Dillberger
Publikováno v:
Toxicologic Pathology. 21:480-489
Vigabatrin (Sabril®) is a γ-aminobutyric acid-transaminase (GABA-T) inhibitor that is effective in the treatment of certain types of drug-resistant or uncontrolled epilepsy but is known to cause microscopic vacuolation (intramyelinic edema) in the
Autor:
John E. Dillberger, Aida M. Cancel, David C. Sokal, Dianne M. Creasy, Catherine M. Kelly, Henry F. Bolte
Publikováno v:
Regulatory toxicology and pharmacology : RTP. 56(2)
This study investigated if quinacrine can induce a tumorigenic response in rats when administered in a manner similar to the intended human use for female non-surgical sterilization. Young sexually mature female rats received two doses of quinacrine
Publikováno v:
Genomics. 90(3)
Osteosarcoma is the most common malignant bone tumor in dogs and, like its human orthologue, is characterized by aggressive local behavior and high metastatic rates. The Scottish deerhound is a breed of dog with a >15% incidence of osteosarcoma and r