Zobrazeno 1 - 10
of 609
pro vyhledávání: '"John E, Wagner"'
Autor:
Sara Bolivar-Wagers, Michael L. Loschi, Sujeong Jin, Govindarajan Thangavelu, Jemma H. Larson, Cameron S. McDonald-Hyman, Ethan G. Aguilar, Asim Saha, Brent H. Koehn, Mehrdad Hefazi, Mark J. Osborn, Michael C. Jensen, John E. Wagner, Christopher A. Pennell, Bruce R. Blazar
Publikováno v:
JCI Insight, Vol 7, Iss 17 (2022)
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) efficacy is complicated by graft-versus-host disease (GVHD), a leading cause of morbidity and mortality. Regulatory T cells (Tregs) have shown efficacy in preventing GVHD. However, high T
Externí odkaz:
https://doaj.org/article/13f49ac28e6643b598a93fee5b351f8a
Autor:
Teresa L. Ramos, Sara Bolivar-Wagers, Sujeong Jin, Govindarajan Thangavelu, Federico Simonetta, Po-Yu Lin, Toshihito Hirai, Asim Saha, Brent Koehn, Leon L. Su, Lora K. Picton, Jeanette Baker, Juliane K. Lohmeyer, Megan Riddle, Cindy Eide, Jakub Tolar, Angela Panoskaltsis-Mortari, John E. Wagner, K. Christopher Garcia, Robert S. Negrin, Bruce R. Blazar
Publikováno v:
Blood. 141:1337-1352
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is a curative option for patients with hematological disorders and bone marrow (BM) failure syndromes. Graft-versus-host disease (GVHD) remains a leading cause of morbidity posttransplant
Publikováno v:
Forest Science. 69:10-23
There has been increasing interest among foresters and landowners in modifying existing even-aged forest structures to multi-aged or uneven-aged structures. Maintaining a continuous forest structure often provides a wider array of forest values over
Autor:
Ashish O. Gupta, John E. Wagner
Publikováno v:
Frontiers in Pediatrics, Vol 8 (2020)
Hematopoietic cell transplants using stem cells from umbilical cord blood are used worldwide for the treatment of malignant and non-malignant disorders. Transplant procedures from this stem cell source have shown promising outcomes in successfully tr
Externí odkaz:
https://doaj.org/article/506441796c194e208bafe72bce6929dd
Autor:
Miguel-Angel Perales, Benjamin Tomlinson, Mei-Jie Zhang, Andrew St. Martin, Amer Beitinjaneh, John Gibson, William Hogan, Natasha Kekre, Hillard Lazarus, David Marks, Joseph McGuirk, Rizwan Romee, Melhem Solh, John E. Wagner, Daniel J. Weisdorf, Marcos de Lima, Mary Eapen
Publikováno v:
Haematologica, Vol 105, Iss 2 (2020)
We sought to study whether survival after haploidentical transplantation is comparable to that after matched unrelated donor transplantation for 822 patients aged 50-75 years with acute myeloid leukemia in first or second complete remission. One hund
Externí odkaz:
https://doaj.org/article/82f3f5402b6740588c81999290939ab2
Autor:
Nelli Bejanyan, Claudio G. Brunstein, Qing Cao, Aleksandr Lazaryan, Xianghua Luo, Julie Curtsinger, Rohtesh S. Mehta, Erica Warlick, Sarah A. Cooley, Bruce R. Blazar, Jeffrey S. Miller, Daniel Weisdorf, John E. Wagner, Michael R. Verneris
Publikováno v:
Blood Advances, Vol 2, Iss 8, Pp 909-922 (2018)
Abstract: Slow immune reconstitution is a major obstacle to the successful use of allogeneic hematopoietic cell transplantation (allo-HCT). As matched sibling donor (MSD) allo-HCT is regarded as the gold standard, we evaluated the pace of immune reco
Externí odkaz:
https://doaj.org/article/445e1125ac304426a5ced8cc55bc111d
Autor:
Andrew L. H. Webster, Mathijs A. Sanders, Krupa Patel, Ralf Dietrich, Raymond J. Noonan, Francis P. Lach, Ryan R. White, Audrey Goldfarb, Kevin Hadi, Matthew M. Edwards, Frank X. Donovan, Remco M. Hoogenboezem, Moonjung Jung, Sunandini Sridhar, Tom F. Wiley, Olivier Fedrigo, Huasong Tian, Joel Rosiene, Thomas Heineman, Jennifer A. Kennedy, Lorenzo Bean, Rasim O. Rosti, Rebecca Tryon, Ashlyn-Maree Gonzalez, Allana Rosenberg, Ji-Dung Luo, Thomas S. Carroll, Sanjana Shroff, Michael Beaumont, Eunike Velleuer, Jeff C. Rastatter, Susanne I. Wells, Jordi Surrallés, Grover Bagby, Margaret L. MacMillan, John E. Wagner, Maria Cancio, Farid Boulad, Theresa Scognamiglio, Roger Vaughan, Kristin G. Beaumont, Amnon Koren, Marcin Imielinski, Settara C. Chandrasekharappa, Arleen D. Auerbach, Bhuvanesh Singh, David I. Kutler, Peter J. Campbell, Agata Smogorzewska
Publikováno v:
Nature, 612(7940), 495-502. Nature Publishing Group
Nature
Nature
Fanconi anaemia (FA), a model syndrome of genome instability, is caused by a deficiency in DNA interstrand crosslink repair resulting in chromosome breakage1–3. The FA repair pathway protects against endogenous and exogenous carcinogenic aldehydes4
Publikováno v:
FASEB BioAdvances, Vol 3, Iss 10, Pp 802-813 (2021)
FASEB BioAdvances
FASEB BioAdvances
A hallmark of endometriosis – a chronic debilitating condition whose causes are poorly understood – is neuronal innervation of lesions. Recent evidence demonstrates that the peripheral nervous system plays an important role in the pathophysiology
Autor:
F. Bernaudin, Damiano Rondelli, Julie Kanter, Teonna L Woolford, Julie A. Panepinto, Courtney D. Fitzhugh, John F. Tisdale, Javier Bolaños-Meade, Shalini Shenoy, Jane S. Hankins, John E. Wagner, Robert I. Liem, Mark C. Walters, Joerg J Meerpohl, M. Hassan Murad
Publikováno v:
Blood Adv
Background: Sickle cell disease (SCD) is a life-limiting inherited hemoglobinopathy that results in significant complications and affects quality of life. Hematopoietic stem cell transplantation (HSCT) is currently the only curative intervention for
Autor:
Sarah C. Merkel, Frank Cichocki, Mark J. Osborn, Margaret L. MacMillan, Scott N. Furlan, Leslie S. Kean, Jeffrey S. Miller, John E. Wagner, Sophia Hani, Rahul Roychoudhuri, Ena Wang, Bruce R. Blazar, Yigang Zhang, Keli L. Hippen, Nicholas P. Restifo
Publikováno v:
Cytotherapy. 23:704-714
Background aims Adoptive transfer of suppressive CD4+CD25+ thymic regulatory T cells (tTregs) can control auto- and alloimmune responses but typically requires in vitro expansion to reach the target cell number for efficacy. Although the adoptive tra