Zobrazeno 1 - 10
of 131
pro vyhledávání: '"John E, O'Brien"'
Autor:
Eavan C. McLoughlin, Dr. John E. O'Brien, Dr. Cristina Trujillo, Prof. Mary J. Meegan, Prof. Niamh M. O'Boyle
Publikováno v:
ChemistryOpen, Vol 12, Iss 6, Pp n/a-n/a (2023)
Abstract Trans‐β‐lactam isomers have garnered much attention as anti‐cancer microtubule targeting agents. Currently available synthetic methods are available for the preparation of enantiopure β‐lactams and favour isomeric cis/trans β‐la
Externí odkaz:
https://doaj.org/article/19958ee7f0264becb96843468f6b8e7b
Autor:
John E. O'Brien
In his Critique of Rationality, John Eustice O'Brien proposes a fascinating rectification for the distortion of technical necessity in Western Society due to unbridled instrumental reason. He begins with a review of this issue first raised by the Ear
Autor:
John E. O'Brien
Using the historical-materialist method to unravel the promise and limits of critical practice since the Revolutionary Age, John E. O'Brien investigates the problems and prospects of cultural criticism for the 21st century through absorbing studies o
Autor:
Andrew J. Byrne, Sandra A. Bright, James P. McKeown, John E. O’Brien, Brendan Twamley, Darren Fayne, D. Clive Williams, Mary J. Meegan
Publikováno v:
Pharmaceuticals, Vol 13, Iss 1, p 16 (2020)
Lymphomas (cancers of the lymphatic system) account for 12% of malignant diseases worldwide. Burkitt’s lymphoma (BL) is a rare form of non-Hodgkin’s lymphoma in which the cancer starts in the immune B-cells. We report the synthesis and preliminar
Externí odkaz:
https://doaj.org/article/e347fc61fc9f415796bc0140917546d5
Publikováno v:
ChemistrySelect. 6:9663-9668
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d3dc3b1540c5c94f80d0bbf975f0618
https://doi.org/10.1002/slct.202102576
https://doi.org/10.1002/slct.202102576
Publikováno v:
ChemistryOpen.
Trans-β-lactam isomers have garnered much attention as anti-cancer microtubule targeting agents. Currently available synthetic methods are available for the preparation of enantiopure β-lactams and favour isomeric cis/trans β-lactam mixtures. Indi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b9557239a74526a67cbb91515b5d63f
https://pubmed.ncbi.nlm.nih.gov/35876400
https://pubmed.ncbi.nlm.nih.gov/35876400
Publikováno v:
Chemistry (Weinheim an Der Bergstrasse, Germany)
Atropisomerism is a fundamental feature of substituted biaryls resulting from rotation around the biaryl axis. Different stereoisomers are formed due to restricted rotation about the single bond, a situation often found in substituted porphyrins. Pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86dd8915ac5bbe5d3c1941edd21a6e52
https://doi.org/10.1002/chem.202003414
https://doi.org/10.1002/chem.202003414
Autor:
Karolis Norvaiša, John E. O’Brien, Irina Osadchuk, Brendan Twamley, Victor Borovkov, Mathias O. Senge
Publikováno v:
Chemical Communication
Recently prochiral solvating agents (pro-CSA) became a spotlight for the detection of enantiopurity by NMR. Chemical shift non-equivalency in achiral hosts introduced by the presence of chiral guest yields observable resonance signal splitting correl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f177c6a0d8c742310e777faeff21d5c
Autor:
Ligia C. Gomes-da-Silva, Mathias O. Senge, John E. O'Brien, Karolis Norvaiša, Brendan Twamley, Sophie Maguire, Claire L. Donohoe
Publikováno v:
Chemistry Europe
Inspired by the rigidified architecture of 'picket-fence' systems, we propose a strategy utilizing strain to impose intramolecular tension in already peripherally overcrowded structures leading to selective atropisomeric conversion. Employing this ap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1ae4f72bcdc53d74346c62393e3a693
https://pubmed.ncbi.nlm.nih.gov/34792217
https://pubmed.ncbi.nlm.nih.gov/34792217
Autor:
Audrey O’Donnell, Gavin McLaughlin, Carol Downey, John E. O'Brien, Geraldine O'Neill, Pierce V. Kavanagh
Publikováno v:
Drug testing and analysisREFERENCES. 14(3)
Benzodiazepines are a class of compounds used clinically to treat a variety of conditions including anxiety and insomnia. Their potential for abuse has led to a surge in their availability on the illegal drugs market. End users often rely on markings
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca7b0c1cd5313c9daa330ecd380bedb5
https://pubmed.ncbi.nlm.nih.gov/34825517
https://pubmed.ncbi.nlm.nih.gov/34825517