Effect of losartan on performance and physiological responses to exercise at high altitude (5035 m)

Autor: Arthur R Bradwell, John Delamere, Owen D Thomas, Samuel J E Lucas, Stephen D Myers, Brian Johnson, Mark Edsell, Charles Newman, Patrick Cadigan, William L Malein, Kimberly M Ashdown, Carla A Rue, Kelsey E Joyce, Fiona A Myers, Alexander D Wright, Chris H E Imray

Publikováno v: BMJ Open Sport & Exercise Medicine, Vol 7, Iss 1 (2021)

Objective Altitude-related and exercise-related elevations in blood pressure (BP) increase the likelihood of developing pulmonary hypertension and high-altitude illness during high-altitude sojourn. This study examined the antihypertensive effect and

Externí odkaz: https://doaj.org/article/add5a789176f482e96d2832bb3c82f32

Acetazolamide reduces exercise capacity following a 5-day ascent to 4559 m in a randomised study

Autor: Arthur R Bradwell, Kimberley Ashdown, Carla Rue, John Delamere, Owen D Thomas, Samuel J E Lucas, Alex D Wright, Stephen J Harris, Stephen D Myers

Publikováno v: BMJ Open Sport & Exercise Medicine, Vol 4, Iss 1 (2018)

Objective To assess whether acetazolamide (Az), used prophylactically for acute mountain sickness (AMS), alters exercise capacity at high altitude.Methods Az (500 mg daily) or placebo was administered to 20 healthy adults (aged 36±20 years, range 21

Externí odkaz: https://doaj.org/article/add0e9ac9d6641849b002fa349f28f2b

Effect of losartan on performance and physiological responses to exercise at high altitude (5035 m)

Autor: Owen Thomas, Stephen D. Myers, Kimberly M. Ashdown, Kelsey E. Joyce, Charles Newman, Carla A. Rue, William L. Malein, Samuel J. E. Lucas, Arthur R. Bradwell, Patrick Cadigan, Alex D. Wright, John Delamere, Brian G. Johnson, Fiona A. Myers, Mark E. Edsell, Christopher H.E. Imray

Publikováno v: Lucas, S J E, Malein, W L, Thomas, O D, Ashdown, K M, Rue, C A, Joyce, K E, Newman, C, Cadigan, P, Johnson, B, Myers, S D, Myers, F A, Wright, A D, Delamere, J, Imray, C H E, Bradwell, A R & Edsell, M 2021, ' Effect of losartan on performance and physiological responses to exercise at high altitude (5035 m) ', BMJ Open Sport and Exercise Medicine, vol. 7, no. 1, e000982 . https://doi.org/10.1136/bmjsem-2020-000982
BMJ Open Sport & Exercise Medicine, Vol 7, Iss 1 (2021)
BMJ Open Sport — Exercise Medicine

ObjectiveAltitude-related and exercise-related elevations in blood pressure (BP) increase the likelihood of developing pulmonary hypertension and high-altitude illness during high-altitude sojourn. This study examined the antihypertensive effect and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27ed02f08b799d12612b73524950e98f

Hypoxia is not the primary mechanism contributing to exercise-induced proteinuria

Autor: John Delamere, Brian G. Johnson, Susie B. Bradwell, Will Malein, Kimberley Ashdown, Arthur R. Bradwell, Mark Edsell, Alex D. Wright, Kelsey E. Joyce, Amy Fountain, Carla A. Rue, Stephen D. Myers, Charles Newman, Patrick Cadigan, Christopher T. Lewis, Owen Thomas, Samuel J. E. Lucas, Christopher H.E. Imray, Fiona A. Myers, Alexander J. Clarke

Publikováno v: Joyce, K E, Delamere, J, Bradwell, S, Myers, S D, Ashdown, K, Rue, C, Lucas, S J E, Thomas, O D, Fountain, A, Edsell, M, Myers, F, Malein, W, Imray, C, Clarke, A, Lewis, C T, Newman, C, Johnson, B, Cadigan, P, Wright, A & Bradwell, A 2020, ' Hypoxia is not the primary mechanism contributing to exercise-induced proteinuria ', BMJ Open Sport and Exercise Medicine, vol. 6, no. 1, e000662 . https://doi.org/10.1136/bmjsem-2019-000662
BMJ Open Sport — Exercise Medicine
BMJ Open Sport & Exercise Medicine, Vol 6, Iss 1 (2020)

IntroductionProteinuria increases at altitude and with exercise, potentially as a result of hypoxia. Using urinary alpha-1 acid glycoprotein (α1-AGP) levels as a sensitive marker of proteinuria, we examined the impact of relative hypoxia due to high

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e986db693808a349f1795a8917468b63
https://doi.org/10.1136/bmjsem-2019-000662

Acetazolamide reduces exercise capacity following a 5-day ascent to 4559 m in a randomised study

Autor: John Delamere, Carla A. Rue, Alex D. Wright, Stephen Harris, Arthur R. Bradwell, Kimberley Ashdown, Samuel J. E. Lucas, Owen Thomas, Stephen D. Myers

Publikováno v: BMJ Open Sport — Exercise Medicine

ObjectiveTo assess whether acetazolamide (Az), used prophylactically for acute mountain sickness (AMS), alters exercise capacity at high altitude.MethodsAz (500 mg daily) or placebo was administered to 20 healthy adults (aged 36±20 years, range 21�

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d310ee17598fff9ed8770579c8a31451
https://doi.org/10.1136/bmjsem-2017-000302