Zobrazeno 1 - 10
of 25
pro vyhledávání: '"John David Sinclair"'
Publikováno v:
Behavioral Neuroscience. 118:1089-1096
Three experiments examined the effect of acute naltrexone treatment on both taste reactivity and consumption of ethanol in high ethanol-preferring rat lines: Alko Alcohol-Accepting (AA) rats (Experiments 1 and 2) and Alcohol-Preferring (P) rats (Expe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60990eaff85422c7fb5705fc8fd0f1dd
https://doi.org/10.1037/0735-7044.118.5.1089
https://doi.org/10.1037/0735-7044.118.5.1089
Autor:
John David Sinclair
Publikováno v:
Alcohol and Alcoholism. 36:2-10
Eight double-blind placebo-controlled clinical trials in five countries have demonstrated the safety and efficacy of naltrexone as an adjunct in alcoholism treatment. The efficacy depends, however, on how naltrexone is used. Three of the trials teste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8911a7618cb4b288222c49f44b180cae
https://doi.org/10.1093/alcalc/36.1.2
https://doi.org/10.1093/alcalc/36.1.2
Publikováno v:
Pharmacology Biochemistry and Behavior. 52:29-34
The role of central monoamines in the genetically determined influences on voluntary ethanol consumption were examined by studying the extracellular levels of monoamines in the nucleus accumbens of the alcohol-preferring AA (Alko Alcohol) and alcohol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52c9d82f2a5b0ec09b438039610fe3df
https://doi.org/10.1016/0091-3057(95)00097-g
https://doi.org/10.1016/0091-3057(95)00097-g
Publikováno v:
Alcohol. 11:315-321
A microdialysis system for measuring the ethanol concentration curve in the nucleus accumbens of the rat brain was developed and tested in three different rat lines (AA, ANA, and Wistar) after an intraperitoneal (IP) and an intragastric (IG) dose of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a503585b1e4324aaae1b8d8af39edb5d
https://doi.org/10.1016/0741-8329(94)90098-1
https://doi.org/10.1016/0741-8329(94)90098-1
Autor:
John David Sinclair, Pekka Sillanaukee
Publikováno v:
Addiction. 88:591-595
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c81cb2bda97eb9d163532c5bf697130
https://doi.org/10.1111/j.1360-0443.1993.tb02068.x
https://doi.org/10.1111/j.1360-0443.1993.tb02068.x
Publikováno v:
Alcohol. 9:155-160
Alcohol-avoiding (ANA), alcohol-preferring (AA), and control Wistar rats were tested sequentially for their initial preferences for single concentration solutions of quinine, saccharin, salt, and citric acid, and then for an ascending series of sacch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::697d4a98fa22fd4e98ebe0d5471cf0b8
https://doi.org/10.1016/0741-8329(92)90027-8
https://doi.org/10.1016/0741-8329(92)90027-8
Autor:
Sören V. Siegmund, Ting-Kai Li, John David Sinclair, Manfred V. Singer, Rainer Spanagel, Valentina Vengeliene
Publikováno v:
Alcoholism, clinical and experimental research. 27(7)
Background: Voluntary alcohol intake in rats can be influenced by alcohol deprivation phases and stress. We investigated the magnitude of the effects of both deprivation and stress (forced swimming in cold water and foot-shock had been chosen as stre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50a8789a11cdd143a23accbede74416a
https://pubmed.ncbi.nlm.nih.gov/12878910
https://pubmed.ncbi.nlm.nih.gov/12878910
Publikováno v:
The New England journal of medicine. 346(17)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::18cf296ee133a5f65ff841d91bcbb201
https://pubmed.ncbi.nlm.nih.gov/11973854
https://pubmed.ncbi.nlm.nih.gov/11973854