Zobrazeno 1 - 2
of 2
pro vyhledávání: '"John David Jeppson"'
Autor:
Othman Ghribi, Salvador Soriano, Wolff M. Kirsch, John David Jeppson, Harry V. Vinters, Nicholas Sanchez, Brendan Gongol, Karina Mayagoitia, Samuel Shin, Traci L. Marin, Christopher G. Wilson
Publikováno v:
Scientific reports, vol 7, iss 1
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Scientific Reports
The function of the amyloid precursor protein (APP) in brain health remains unclear. This study elucidated a novel cytoprotective signaling pathway initiated by the APP transcriptionally active intracellular domain (AICD) in response to 27-hydroxycho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11efb290041447dfb712e3a0f45794b8
https://escholarship.org/uc/item/4sz093nr
https://escholarship.org/uc/item/4sz093nr
Publikováno v:
BMC Neurology
Background: High-profile Phase 3 clinical trials of bapineuzumab and solanezumab, antibodies targeted at amyloid-beta (Aβ) removal, have failed to meet their primary endpoints. Neit her drug improves clinical outcomes in patients with late onset AD,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a1d684c18f7898bd1dea831981800bd
https://pubmed.ncbi.nlm.nih.gov/25179671
https://pubmed.ncbi.nlm.nih.gov/25179671
