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pro vyhledávání: '"John Damrath"'
Publikováno v:
Journal of Bone and Mineral Research. 37:1297-1306
Chronic kidney disease (CKD) affects 15% of Americans and greatly increases fracture risk due to elevated parathyroid hormone, cortical porosity, and reduced bone material quality. Calcimimetic drugs are used to lower parathyroid hormone (PTH) in CKD
Autor:
Alyson L. Essex, Joshua R. Huot, Padmini Deosthale, Alison Wagner, Jorge Figueras, Azaria Davis, John Damrath, Fabrizio Pin, Joseph Wallace, Andrea Bonetto, Lilian I. Plotkin
Publikováno v:
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 37(7)
Previous studies proposed the Triggering Receptor Expressed on Myeloid Cells 2 (TREM2), a receptor expressed in myeloid cells including microglia in brain and osteoclasts in bone, as a link between brain and bone disease. The TREM2 R47H variant is a
Autor:
C. Simon, Laura Buttitta, John Damrath, Cheng Yu Lee, Caitlin E. Gamble, Chaoyuan Kuang, Krista Golden
Publikováno v:
Development. 141:1453-1464
Cancer stem cells likely survive chemotherapy or radiotherapy by acquiring mutations that inactivate the endogenous apoptotic machinery or by cycling slowly. Thus, knowledge about the mechanisms linking the activation of an alternative cell death mod