Zobrazeno 1 - 10
of 199
pro vyhledávání: '"John D. Pfeifer"'
Publikováno v:
Endocrine Connections, Vol 7, Iss 12, Pp 1226-1235 (2018)
The majority of papillary thyroid carcinoma (PTC) cases comprise classic papillary (C-PTC) and follicular variant (FV-PTC) histologic sub-types. Historically, clinical equivalency was assumed, but recent data suggest C-PTC may have poorer outcomes. H
Externí odkaz:
https://doaj.org/article/2272820b235b40dbafc26b47e85c641c
Autor:
Ta-Chiang Liu, Kelley VanBuskirk, Syed A Ali, M Paul Kelly, Lori R Holtz, Omer H Yilmaz, Kamran Sadiq, Najeeha Iqbal, Beatrice Amadi, Sana Syed, Tahmeed Ahmed, Sean Moore, I Malick Ndao, Michael H Isaacs, John D Pfeifer, Hannah Atlas, Phillip I Tarr, Donna M Denno, Christopher A Moskaluk
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 14, Iss 1, p e0007975 (2020)
BackgroundA major limitation to understanding the etiopathogenesis of environmental enteric dysfunction (EED) is the lack of a comprehensive, reproducible histologic framework for characterizing the small bowel lesions. We hypothesized that the devel
Externí odkaz:
https://doaj.org/article/c1b0dd36aa384bf6be66f36831be9806
Autor:
Lulu Sun, Jessica S. Petrone, Samantha N. McNulty, Michael J. Evenson, Xiaopei Zhu, Joshua A. Robinson, Rebecca D. Chernock, Eric J. Duncavage, John D. Pfeifer
Publikováno v:
Human Pathology. 123:1-10
Salivary gland neoplasms may pose diagnostic difficulties due to overlapping morphologic features. Recently, specific gene fusions have been discovered that correspond to particular tumor types, and can aid in accurate diagnosis. Gene rearrangements
Autor:
Lulu, Sun, Molly C, Schroeder, Ian S, Hagemann, John D, Pfeifer, Julie K, Schwarz, Perry W, Grigsby, Stephanie, Markovina, Alexander J, Lin
Publikováno v:
International Journal of Gynecological Pathology. 41:628-635
There have been few clinically useful targetable biomarkers in uterine cervical carcinomas. Estrogen receptor (ER), HER2, and fibroblast activation protein (FAP) are potential therapeutic or theranostic targets in other gynecologic and genitourinary
Autor:
Jason N. Rosenbaum, Anna B. Berry, Alanna J. Church, Kristy Crooks, David Wu, Dolores Lopez-Terrada, John D. Pfeifer, Jeffrey Gagan, Iris Schrijver, Anthony N. Snow, Mark D. Ewalt, Hanna Rennert
Publikováno v:
The Journal of Molecular Diagnostics. 23:1218-1240
Molecular genetic pathology (MGP) is a subspecialty of pathology and medical genetics and genomics. Genomic testing, which is defined as that which generates large data sets and interrogates large segments of the genome in a single assay, is increasi
Autor:
Molly Y Hansen, Karl V. Voelkerding, John A. Thorson, John D. Pfeifer, Allison M. Cushman-Vokoun, Marilyn M. Li, Damon R Olson, Josh Lauring, Sophia Yohe, Gail H. Vance, James D. Barbeau, Pranil Chandra, Jonathan Myles, Brad W Jensen, Anna B. Berry
Publikováno v:
Archives of Pathology & Laboratory Medicine. 146:70-77
Context.— Next-generation sequencing is a powerful clinical tool for cancer management but can produce incidental/secondary findings that require special consideration. Objective.— To discuss clinical and laboratory issues related to incidental o
Autor:
Jennifer M. Yoest, Eric J. Duncavage, Samantha N. McNulty, Meaghan Riley, John D. Pfeifer, Michael J. Evenson, Meagan Corliss, Jonathan W. Heusel
Publikováno v:
The Journal of Molecular Diagnostics. 23:200-211
Severe congenital neutropenia (SCN) is a collection of diverse disorders characterized by chronically low absolute neutrophil count in the peripheral blood, increased susceptibility to infection, and a significant predisposition to the development of
Autor:
Carina Dehner, Jason Kenney, Lulu Sun, Horacio M. Maluf, John D. Pfeifer, Xiaopei Zhu, Samantha M McNulty, John S.A. Chrisinger
Publikováno v:
Virchows Archiv. 478:757-765
Phosphaturic mesenchymal tumors (PMT) are rare neoplasms characterized by secretion of FGF23, resulting in renal phosphate wasting and osteomalacia. This tumor-induced osteomalacia (TIO) is cured by complete resection; thus, diagnosis is important, p
Autor:
Dale R. Balce, Megan T. Baldridge, Herbert W. Virgin, Qun Lu, Chandni Desai, Konstantin Zaitsev, Lindsay Droit, Craig B. Wilen, Sunmin Park, Darren Kreamalmeyer, Shan Li, Maxim N. Artyomov, Ki-Wook Kim, Christina L. Stallings, Anthony Orvedahl, John D. Pfeifer, Ya-Ting Wang, Scott A. Handley, Robert C. Orchard, W. Timothy Schaiff
Publikováno v:
Nature microbiology
Innate and adaptive immune responses that prime myeloid cells, such as macrophages, protect against pathogens1,2. However, if left uncontrolled, these responses may lead to detrimental inflammation3. Macrophages, particularly those resident in tissue
Autor:
Lulu Sun, John D. Pfeifer
Publikováno v:
Seminars in Diagnostic Pathology. 36:342-354
Molecular diagnostic techniques are part of the ancillary arsenal of anatomic pathologists. Advances in technology and knowledge regarding disease pathogenesis, tumorigenesis, and immune function contribute to the development of these assays. However