Zobrazeno 1 - 10
of 68
pro vyhledávání: '"John D. O'Neill"'
Autor:
Meghan R. Pinezich, Mohammad Mir, Jonathan A. Reimer, Sarah R. Kaslow, Jiawen Chen, Brandon A. Guenthart, Matthew Bacchetta, John D. O'Neill, Gordana Vunjak‐Novakovic, Jinho Kim
Publikováno v:
Bioengineering & Translational Medicine, Vol 8, Iss 1, Pp n/a-n/a (2023)
Abstract Pulmonary air leak is the most common complication of lung surgery, with air leaks that persist longer than 5 days representing a major source of post‐surgery morbidity. Clinical management of air leaks is challenging due to limited method
Externí odkaz:
https://doaj.org/article/381367de965447ddb8c74380bf68bd43
Autor:
Brandon A. Guenthart, John D. O’Neill, Jinho Kim, Dawn Queen, Scott Chicotka, Kenmond Fung, Michael Simpson, Rachel Donocoff, Michael Salna, Charles C. Marboe, Katherine Cunningham, Susan P. Halligan, Holly M. Wobma, Ahmed E. Hozain, Alexander Romanov, Gordana Vunjak-Novakovic, Matthew Bacchetta
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Gastric aspiration severely injures donor lungs, frequently making them unacceptable for transplantation. Here the authors show that an interventional cross-circulation platform enables the regeneration of severely damaged lungs in a swine model of g
Externí odkaz:
https://doaj.org/article/d5b8dc81c66442c485f24ef1186a3a1f
Autor:
Eylem Kulkoyluoglu Cotul, Qianying Zuo, Ashlie Santaliz-Casiano, Ozan Berk Imir, Ayca Nazli Mogol, Elif Tunc, Kevin Duong, Jenna Kathryn Lee, Rithva Ramesh, Elijah Odukoya, Mrinali P. Kesavadas, Monika Ziogaite, Brandi Patrice Smith, Chengjian Mao, David J. Shapiro, Ben Ho Park, Benita S. Katzenellenbogen, Drew Daly, Evelyn Aranda, John D. O’Neill, Christopher Walker, Yosef Landesman, Zeynep Madak-Erdogan
Publikováno v:
Cancers, Vol 12, Iss 9, p 2397 (2020)
The majority of breast cancer specific deaths in women with estrogen receptor positive (ER+) tumors occur due to metastases that are resistant to therapy. There is a critical need for novel therapeutic approaches to achieve tumor regression and/or ma
Externí odkaz:
https://doaj.org/article/87243b4591a14484aca866d16781cc46
Autor:
Meghan R. Pinezich, Manuel A. Tamargo, Sharon Fleischer, Jonathan A. Reimer, Maria R. Hudock, Ahmed E. Hozain, Sarah R. Kaslow, Yuliya Tipograf, Rajesh Kumar Soni, Olimpia P. Gavaudan, Brandon A. Guenthart, Charles C. Marboe, Matthew Bacchetta, John D. O'Neill, N. Valerio Dorrello, Gordana Vunjak-Novakovic
Publikováno v:
J Cyst Fibros
Manifestations of cystic fibrosis, although well-characterized in the proximal airways, are understudied in the distal lung. Characterization of the cystic fibrosis lung 'matrisome' (matrix proteome) has not been previously described, and could help
Autor:
Zeynep Madak Erdogan, Debu Tripathy, Akshara Singareeka Raghavendra, John D. O'Neill, Evelyn Aranda, Benita S. Katzenellenbogen, Yvonne Ziegler, Ben Ho Park, David J. Shapiro, Nicole Hwajin Park, Eylem Kulkoyluoglu-Cotul, Ozan Berk Imir, Jenny Drnevich, Christine Chien, Ashlie Santaliz Casiano, Yu-Jeh Liu, Ayca Nazli Mogol, Qianying Zuo
Supplementary Table from Targeting Metabolic Adaptations in the Breast Cancer–Liver Metastatic Niche Using Dietary Approaches to Improve Endocrine Therapy Efficacy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08fcbd670914710b64958120b07b5ee2
https://doi.org/10.1158/1541-7786.22528229.v1
https://doi.org/10.1158/1541-7786.22528229.v1
Autor:
Zeynep Madak Erdogan, Debu Tripathy, Akshara Singareeka Raghavendra, John D. O'Neill, Evelyn Aranda, Benita S. Katzenellenbogen, Yvonne Ziegler, Ben Ho Park, David J. Shapiro, Nicole Hwajin Park, Eylem Kulkoyluoglu-Cotul, Ozan Berk Imir, Jenny Drnevich, Christine Chien, Ashlie Santaliz Casiano, Yu-Jeh Liu, Ayca Nazli Mogol, Qianying Zuo
Estrogen receptor–positive (ER+) metastatic tumors contribute to nearly 70% of breast cancer–related deaths. Most patients with ER+ metastatic breast cancer (MBC) undergo treatment with the estrogen receptor antagonist fulvestrant as standard of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10b4132d6b56eba42f1eb12d4ae2f62b
https://doi.org/10.1158/1541-7786.c.6545651.v1
https://doi.org/10.1158/1541-7786.c.6545651.v1
Autor:
Seyed Mohammad, Mir, Jiawen, Chen, Meghan R, Pinezich, John D, O'Neill, Sarah X L, Huang, Gordana, Vunjak-Novakovic, Jinho, Kim
Publikováno v:
Lab Chip
Recent synergistic advances in organ-on-chip and tissue engineering technologies offer opportunities to create in vitro-grown tissue or organ constructs that can faithfully recapitulate their in vivo counterparts. Such in vitro tissue or organ constr
Autor:
Seyed Mohammad Mir, Jiawen Chen, Meghan R. Pinezich, John D. O'Neill, Sarah X. L. Huang, Gordana Vunjak-Novakovic, Jinho Kim
Publikováno v:
Lab on a Chip. 22:1018-1031
An imaging-enabled rat trachea bioreactor is developed that can permit controllable in vitro epithelium replacement, in situ cell monitoring, and long-term tissue scaffold cultivation.
Autor:
John W. Stokes, Matthew Bacchetta, Gordana Vunjak-Novakovic, Clayne Benson, Jennifer Talackine, Jonathan A. Reimer, Sophoclis P. Alexopoulos, John D. O’Neill, Michael J. Lee, Charles R. Flynn, Rei Ukita, Ahmed E. Hozain, Andrew Tumen, Nancy L. Cardwell, Meghan R. Pinezich, Wei Kelly Wu
Publikováno v:
ASAIO J
Although machine perfusion has gained momentum as an organ preservation technique in liver transplantation, persistent organ shortages and high waitlist mortality highlight unmet needs for improved organ salvage strategies. Beyond preservation, extra
Autor:
W. Kelly Wu, Brandon A. Guenthart, John D. O'Neill, Ahmed E. Hozain, Yuliya Tipograf, Rei Ukita, John W. Stokes, Yatrik J. Patel, Meghan Pinezich, Jennifer R. Talackine, Nancy L. Cardwell, Kenmond Fung, Gordana Vunjak-Novakovic, Matthew Bacchetta
Publikováno v:
J Heart Lung Transplant
BACKGROUND: Xenogeneic cross-circulation (XC) is an experimental method for ex vivo organ support and recovery that could expand the pool of donor lungs suitable for transplantation. The objective of this study was to establish and validate a standar