Zobrazeno 1 - 10
of 39
pro vyhledávání: '"John D. McPherson"'
Autor:
Mirna Lechpammer, Austin Todd, Vivian Tang, Taryn Morningstar, Alexander Borowsky, Kiarash Shahlaie, John A. Kintner, John D. McPherson, John W. Bishop, Farzad Fereidouni, Zachary T. Harmany, Nicholas Coley, David Zagzag, Jason W. H. Wong, Jiang Tao, Luke B. Hesson, Leslie Burnett, Richard Levenson
Publikováno v:
Brain Sciences, Vol 14, Iss 1, p 108 (2024)
Whereas traditional histology and light microscopy require multiple steps of formalin fixation, paraffin embedding, and sectioning to generate images for pathologic diagnosis, Microscopy using Ultraviolet Surface Excitation (MUSE) operates through UV
Externí odkaz:
https://doaj.org/article/199e9290e30d41d68253f83c6c595d64
Autor:
Christina Poh, John D. McPherson, Joseph Tuscano, Qian Li, Arti Parikh-Patel, Christoph F. A. Vogel, Myles Cockburn, Theresa Keegan
Publikováno v:
BMC Medicine, Vol 20, Iss 1, Pp 1-12 (2022)
Abstract Background There is evidence indicating that pesticide exposure is a risk factor for non-Hodgkin lymphoma (NHL) development. However, the association between pesticide exposure and NHL survival is not well-established. Methods Using the Cali
Externí odkaz:
https://doaj.org/article/ec3ef03438e24905b763701143231a12
Autor:
Alex Q. Lee, Hiroaki Konishi, Connie Duong, Sakiko Yoshida, Ryan R. Davis, Jonathan E. Van Dyke, Masami Ijiri, Bridget McLaughlin, Kyoungmi Kim, Yueju Li, Laurel Beckett, Nitin Nitin, John D. McPherson, Clifford G. Tepper, Noriko Satake
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
In leukemia, a distinct subpopulation of cancer-initiating cells called leukemia stem cells (LSCs) is believed to drive population expansion and tumor growth. Failing to eliminate LSCs may result in disease relapse regardless of the amount of non-LSC
Externí odkaz:
https://doaj.org/article/65345325b8c3492586a08bddfb989d5c
Autor:
Syed H. Zaidi, Tabitha A. Harrison, Amanda I. Phipps, Robert Steinfelder, Quang M. Trinh, Conghui Qu, Barbara L. Banbury, Peter Georgeson, Catherine S. Grasso, Marios Giannakis, Jeremy B. Adams, Elizabeth Alwers, Efrat L. Amitay, Richard T. Barfield, Sonja I. Berndt, Ivan Borozan, Hermann Brenner, Stefanie Brezina, Daniel D. Buchanan, Yin Cao, Andrew T. Chan, Jenny Chang-Claude, Charles M. Connolly, David A. Drew, Alton Brad Farris, Jane C. Figueiredo, Amy J. French, Charles S. Fuchs, Levi A. Garraway, Steve Gruber, Mark A. Guinter, Stanley R. Hamilton, Sophia Harlid, Lawrence E. Heisler, Akihisa Hidaka, John L. Hopper, Wen-Yi Huang, Jeroen R. Huyghe, Mark A. Jenkins, Paul M. Krzyzanowski, Mathieu Lemire, Yi Lin, Xuemei Luo, Elaine R. Mardis, John D. McPherson, Jessica K. Miller, Victor Moreno, Xinmeng Jasmine Mu, Reiko Nishihara, Nickolas Papadopoulos, Danielle Pasternack, Michael J. Quist, Adilya Rafikova, Emma E. G. Reid, Eve Shinbrot, Brian H. Shirts, Lincoln D. Stein, Cherie D. Teney, Lee Timms, Caroline Y. Um, Bethany Van Guelpen, Megan Van Tassel, Xiaolong Wang, David A. Wheeler, Christina K. Yung, Li Hsu, Shuji Ogino, Andrea Gsur, Polly A. Newcomb, Steven Gallinger, Michael Hoffmeister, Peter T. Campbell, Stephen N. Thibodeau, Wei Sun, Thomas J. Hudson, Ulrike Peters
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Large scale sequencing study is of paramount importance to unravel the heterogeneity of colorectal cancer. Here, the authors sequenced 205 cancer genes in more than 2000 tumours and identified additional mutated driver genes, determined that mutation
Externí odkaz:
https://doaj.org/article/a09dab8e99d844a6a6258b23214b612c
Publikováno v:
JAAD Case Reports, Vol 6, Iss 4, Pp 334-336 (2020)
Externí odkaz:
https://doaj.org/article/63049037f1f24a809dba4ef2a7c5029d
Autor:
Julia F. Hopkins, Veronica Y. Sabelnykova, Joachim Weischenfeldt, Ronald Simon, Jennifer A. Aguiar, Rached Alkallas, Lawrence E. Heisler, Junyan Zhang, John D. Watson, Melvin L. K. Chua, Michael Fraser, Francesco Favero, Chris Lawerenz, Christoph Plass, Guido Sauter, John D. McPherson, Theodorus van der Kwast, Jan Korbel, Thorsten Schlomm, Robert G. Bristow, Paul C. Boutros
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-8 (2017)
In prostate cancer, the role of mutations in the maternally-inherited mitochondrial genome are not well known. Here, the authors demonstrate frequent, age-dependent mitochondrial mutation in prostate cancer. Strong links between mitochondrial and nuc
Externí odkaz:
https://doaj.org/article/60e16080a49e4b41a40aef4ed8595ea3
Autor:
Irina Kalatskaya, Quang M. Trinh, Melanie Spears, John D. McPherson, John M. S. Bartlett, Lincoln Stein
Publikováno v:
Genome Medicine, Vol 9, Iss 1, Pp 1-18 (2017)
Abstract Background A key step in cancer genome analysis is the identification of somatic mutations in the tumor. This is typically done by comparing the genome of the tumor to the reference genome sequence derived from a normal tissue taken from the
Externí odkaz:
https://doaj.org/article/3874531847174a59b6e298ac61eafc3b
Autor:
Renea A. Taylor, Michael Fraser, Julie Livingstone, Shadrielle Melijah G. Espiritu, Heather Thorne, Vincent Huang, Winnie Lo, Yu-Jia Shiah, Takafumi N. Yamaguchi, Ania Sliwinski, Sheri Horsburgh, Alice Meng, Lawrence E. Heisler, Nancy Yu, Fouad Yousif, Melissa Papargiris, Mitchell G. Lawrence, Lee Timms, Declan G. Murphy, Mark Frydenberg, Julia F. Hopkins, Damien Bolton, David Clouston, John D. McPherson, Theodorus van der Kwast, Paul C. Boutros, Gail P. Risbridger, Robert G. Bristow
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Men that carrierBRCA2germline mutations are at risk of developing prostate cancer. Here, the authors analyse the genomes of prostate cancer from these individuals and demonstrate increased genomic instability in comparison to sporadic prostate cancer
Externí odkaz:
https://doaj.org/article/8d920a8293a04405b9542b7f3b199b5c
Autor:
Junfeng Ji, Vivek Sharma, Suxia Qi, Meritxell Espino Guarch, Ping Zhao, Zhiwei Luo, Wenxia Fan, Yu Wang, Faridah Mbabaali, Dante Neculai, Miguel Angel Esteban, John D. McPherson, Nizar N. Batada
Publikováno v:
Stem Cell Reports, Vol 2, Iss 1, Pp 44-51 (2014)
Somatic cells can be reprogrammed to induced pluripotent stem cells (iPSCs) using oncogenic transcription factors. However, this method leads to genetic aberrations in iPSCs via unknown mechanisms, which may limit their clinical use. Here, we demonst
Externí odkaz:
https://doaj.org/article/54bf8bd69ce348f08e3045105f8f2540
Autor:
Jia Qian Wu, Angela M. Garcia, Steven Hulyk, Anna Sneed, Carla Kowis, Ye Yuan, David Steffen, John D. McPherson, Preethi H. Gunaratne, Richard A. Gibbs
Publikováno v:
BioTechniques, Vol 36, Iss 4, Pp 690-700 (2004)
Pseudogenes, alternative transcripts, noncoding RNA, and polymorphisms each add extensive complexity to the mammalian transcriptome and confound estimation of the total number of genes. Despite advanced algorithms for gene prediction and several larg
Externí odkaz:
https://doaj.org/article/56c17997dda040869760d133e867dd0e