Zobrazeno 1 - 7
of 7
pro vyhledávání: '"John D. McClymont"'
Publikováno v:
The Journal of Physical Chemistry. 100:18562-18566
Exposure of aqueous solutions of the sodium salt of DNA to ionizing radiation at 77 K gives trapped electron-loss and electron-gain centers in the stacked bases that were well characterized by EPR spectroscopy. We find that when mitoxanthrone and AQ4
Autor:
Mark E. Malone, Paul M. Cullis, Andrew Mather, Ian D. Podmore, John D. McClymont, Martyn C. R. Symons, Marion C. Sweeney
Publikováno v:
Journal of the Chemical Society, Perkin Transactions 2. :1695
Exposure of a range of DNA samples in various media to 60Co γ-rays at 77 K gives electron-capture centres characterized by an EPR doublet with A(1H) of ca. 16 G. Since the electron-adducts of C and T give very similar doublet EPR spectra in irradiat
Publikováno v:
Journal of the Chemical Society, Faraday Transactions. 86:591
Exposure of intercalated DNA to γ-rays at 77 K gives two radical anions, identified as thymine (T˙–) and intercalator (int˙–) radical anions. Growth of the Int˙– signal follows an exponential law with 50% scavenging of T˙– at ca. 1 : 110
Publikováno v:
J. Chem. Soc., Chem. Commun.. :1859-1861
Addition of low concentrations of Cu2+ ions to aqueous DNA gives units having no detectable e.s.r. spectra which, on exposure to 60Co γ-rays at 77 K, gave a well-defined signal for Cu2+.
Autor:
Martyn C. R. Symons, George D. D. Jones, Marion C. Sweeney, John D. McClymont, Paul M. Cullis
Publikováno v:
ChemInform. 18
Autor:
John D. McClymont, Barry G. Dalgarno, Ian D. Podmore, Paul M. Cullis, Mary Lawson, Martyn C. R. Symons
Publikováno v:
Journal of the Chemical Society, Chemical Communications. :1003
Evidence from e.s.r. spectroscopy for the facile N-protonation of the radical anion of cytosine generated in an aqueous glass, even at 4 K, supports the conclusions that electrons are captured predominantly at thymine when DNA is exposed to ionising
Autor:
George D. D. Jones, John D. McClymont, Martyn C. R. Symons, Marion C. Sweeney, Paul M. Cullis
Publikováno v:
Journal of the Chemical Society, Perkin Transactions 2. :1671
The direct and indirect mechanisms for ionising-radiation-induced damage to deoxyribonucleic acid (DNA) have been probed by e.s.r. spectroscopy and by analysis for strand breaks. Irradiation of frozen aqueous DNA was shown by e.s.r. spectroscopy to g