Zobrazeno 1 - 4
of 4
pro vyhledávání: '"John D. McAnany"'
Autor:
Viktoriya Anokhina, Netty Santoso, John D. McAnany, Jessica H. Ciesla, Hongyu Miao, Thomas A. Hilimire, Benjamin L. Miller
Publikováno v:
Bioorg Med Chem
Ribosomal frameshifting, a process whereby a translating ribosome is diverted from one reading frame to another on a contiguous mRNA, is an important regulatory mechanism in biology and an opportunity for therapeutic intervention in several human dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f07b34aaaf0f7f0cea77fe5ef8a56c0
https://doi.org/10.1016/j.bmc.2019.05.009
https://doi.org/10.1016/j.bmc.2019.05.009
Autor:
John D, McAnany, Benjamin L, Miller
Publikováno v:
Methods in enzymology. 623
The ever-growing number of RNA species that are recognized as having a role in human disease is driving a demand for novel molecular probes and therapeutics. Producing sequence-selective RNA-binding molecules remains a substantial challenge, however.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5c940e23e5e68943ff8aac979897cb5d
https://pubmed.ncbi.nlm.nih.gov/31239058
https://pubmed.ncbi.nlm.nih.gov/31239058
Autor:
Benjamin L. Miller, John D. McAnany
The ever-growing number of RNA species that are recognized as having a role in human disease is driving a demand for novel molecular probes and therapeutics. Producing sequence-selective RNA-binding molecules remains a substantial challenge, however.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71490f46a9e805e1ddc9a71fa1ebd758
https://doi.org/10.1016/bs.mie.2019.05.012
https://doi.org/10.1016/bs.mie.2019.05.012
Dynamic Combinatorial Chemistry (DCC) has proven to be a reliable method for identifying hit compounds for target nucleic acid (DNA and RNA) sequences. Typically, these hit compounds are subjected to a lengthy process of optimization via traditional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94a0901f8d2bf5bb2657f679d03ae7bd
https://europepmc.org/articles/PMC4972655/
https://europepmc.org/articles/PMC4972655/