Zobrazeno 1 - 10
of 61
pro vyhledávání: '"John D. Kisiday"'
Autor:
Clodagh M. Kearney, Sohrab Khatab, Gerben M. van Buul, Saskia G. M. Plomp, Nicoline M. Korthagen, Margot C. Labberté, Laurie R. Goodrich, John D. Kisiday, P. R. Van Weeren, Gerjo J. V. M. van Osch, Pieter A. J. Brama
Publikováno v:
Frontiers in Veterinary Science, Vol 9 (2022)
BackgroundAllogenic mesenchymal stem cell (MSC) secretome is a novel intra-articular therapeutic that has shown promise in in vitro and small animal models and warrants further investigation.ObjectivesTo investigate if intra-articular allogenic MSC-s
Externí odkaz:
https://doaj.org/article/56e0347c945b41baa95ca7717ed69749
Autor:
John D. Kisiday, Christopher J. Centeno, Neven J. Steinmetz, Dustin R. Berger, C. Wayne McIlwraith
Publikováno v:
The American Journal of Sports Medicine. 49:3404-3413
Background: Umbilical cord (UC) connective tissues contain plastic-adherent, colony forming unit–fibroblasts (CFU-Fs) amenable to culture expansion for potential therapeutic use. Recently, UC-derived allograft products have been made available to p
Autor:
Sidi A. Bencherif, Tengfei He, John D. Kisiday, Kasturi Joshi-Navare, Shikhar Mehta, Boting Li, Ambika G. Bajpayee, Thibault Colombani
Publikováno v:
Tissue Engineering Part A. 27:748-760
Traumatic joint injuries can result in significant cartilage defects, which can greatly increase the risk of osteoarthritis development. Due to the limited self-healing capacity of avascular cartilage, tissue engineering approaches are required for f
Publikováno v:
Stem Cells and Development. 29:110-118
Both bone marrow-derived mesenchymal stem cells (BMDMSCs) and extracorporeal shockwave (ESW) have shown promise for enhancing fracture repair. If exposure of BMDMSCs to ESW enhances osteogenic differentiation, these therapies may be combined in vivo
Autor:
Erin McCready, Jeremiah T. Easley, Makayla Risch, Kevin L. Troyer, James W. Johnson, Benjamin C. Gadomski, Kirk C. McGilvray, John D. Kisiday, Brad B. Nelson
Publikováno v:
Cartilage. 13(1)
Objective. Shoulder pain is commonly attributed to rotator cuff injury or osteoarthritis. Ovine translational models are used to investigate novel treatments aimed at remedying these conditions to prevent articular cartilage degeneration and subseque
Autor:
John D. Kisiday, Suwimol Tangtrongsup
Publikováno v:
Cellular and Molecular Bioengineering. 12:153-163
Introduction Mesenchymal stem cell (MSC) chondrogenesis is associated with increases in intracellular reactive oxygen species (ROS), which may result in oxidative stress that is detrimental to cartilage regeneration. This study evaluated the ability
Publikováno v:
Connective tissue research. 62(6)
Purpose/Aim: Expanded, human connective tissue cells can adopt mesenchymal stromal cell (MSC) properties that are favorable for applications in regenerative medicine. Sheep are used as a large anim...
Autor:
Brad B. Nelson, Benjamin C. Gadomski, Kirk C. McGilvray, Erin McCready, Makayla Risch, John D. Kisiday, Kevin L. Troyer, James Johnson, Jeremiah T. Easley
Publikováno v:
Journal of orthopaedic research : official publication of the Orthopaedic Research SocietyREFERENCES. 39(4)
The knee is the most common site for translational cartilage research in sheep, though topographic features of articular cartilage across surfaces are unspecified. We aimed to characterize the mechanical, morphological, and biochemical properties of
Publikováno v:
J Orthop Res
Platelet-rich plasma is autologous plasma that contains concentrated platelets compared to whole blood. It is relatively inexpensive to produce, can be easily isolated from whole blood, and can be administered while the patient is in the operating ro
Autor:
Laurie R. Goodrich, John A. Schwartz, John D. Kisiday, Daniel A. Grande, Suwimol Tangtrongsup
Publikováno v:
Cartilage
ObjectiveRats are an early preclinical model for cartilage tissue engineering, and a practical species for investigating the effects of aging. However, rats may be a poor aging model for mesenchymal stem cells (MSCs) based on laboratory reports of a