Zobrazeno 1 - 10
of 177
pro vyhledávání: '"John D. Hayball"'
Autor:
Jessica Day, Sophia Otto, Kathy Cash, Preethi Eldi, Pravin Hissaria, Susanna Proudman, Vidya Limaye, John D. Hayball
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
IntroductionHigh Mobility Group Box Protein 1 (HMGB1) is a DNA-binding protein that exerts inflammatory or pro-repair effects upon translocation from the nucleus. We postulate aberrant HMGB1 expression in immune-mediated necrotising myopathy (IMNM).M
Externí odkaz:
https://doaj.org/article/9c08d4c3150848bdbbe1a0cd3c4ccb83
Publikováno v:
Expert Review of Vaccines, Vol 17, Iss 10, Pp 925-934 (2018)
Introduction: With the increasing number of vaccines and vaccine-preventable diseases, the pressure to generate multi-valent and multi-pathogen vaccines grows. Combining individual established vaccines to generate single-shot formulations represents
Externí odkaz:
https://doaj.org/article/2dbf7c5aaf93487fa930b4b90a8ff06c
Uterine B Cells Exhibit Regulatory Properties During the Peri-Implantation Stage of Murine Pregnancy
Autor:
Ruth Marian Guzman-Genuino, Preethi Eldi, Pablo Garcia-Valtanen, John D. Hayball, Kerrilyn R. Diener
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
A successful outcome to pregnancy is dependent on the ability of the maternal uterine microenvironment to regulate inflammation processes and establish maternal tolerance. Recently, B cells have been shown to influence pregnancy outcomes as aberratio
Externí odkaz:
https://doaj.org/article/58929504f1224d3e9f6463ec1316ed0e
Autor:
Natalie A. Prow, Liang Liu, Eri Nakayama, Tamara H. Cooper, Kexin Yan, Preethi Eldi, Jessamine E. Hazlewood, Bing Tang, Thuy T. Le, Yin Xiang Setoh, Alexander A Khromykh, Jody Hobson-Peters, Kerrilyn R. Diener, Paul M. Howley, John D. Hayball, Andreas Suhrbier
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Zika and chikungunya virus are co-circulating in many regions and currently there is no approved vaccine for either virus. Here, the authors engineer one vaccinia virus based vaccine for both, Zika and chikungunya, and show protection from infection
Externí odkaz:
https://doaj.org/article/fb33c22d0fd945c1b4999adae6928f2c
Autor:
Danushka K. Wijesundara, Wenbo Yu, Ben J. C. Quah, Preethi Eldi, John D. Hayball, Kerrilyn R. Diener, Ilia Voskoboinik, Eric J. Gowans, Branka Grubor-Bauk
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
Abstract The use of cost-effective vaccines capable of inducing robust CD8+ T cell immunity will contribute significantly towards the elimination of persistent viral infections and cancers worldwide. We have previously reported that a cytolytic DNA v
Externí odkaz:
https://doaj.org/article/458aba626a294f098ff6f9d7d1461b40
Autor:
Natalie E. Stevens, Marianne J. Chapman, Cara K. Fraser, Tim R. Kuchel, John D. Hayball, Kerrilyn R. Diener
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Abstract Sepsis remains a significant health burden and a major clinical need exists for therapeutics to dampen the excessive and uncontrolled immune activation. Nuclear protein high mobility group box protein 1 (HMGB1) is released following cell dea
Externí odkaz:
https://doaj.org/article/db850342f341408eaced7e104b682ab6
Autor:
Liang Liu, Tamara Cooper, Preethi Eldi, Pablo Garcia-Valtanen, Kerrilyn R. Diener, Paul M. Howley, John D. Hayball
Publikováno v:
BioTechniques, Vol 62, Iss 4, Pp 183-187 (2017)
Recombinant vaccinia viruses (rVACVs) are promising antigen-delivery systems for vaccine development that are also useful as research tools. Two common methods for selection during construction of rVACV clones are (i) co-insertion of drug resistance
Externí odkaz:
https://doaj.org/article/b3404c6f21114b35a0e331a2f981ba5f
Publikováno v:
Viruses, Vol 12, Iss 5, p 569 (2020)
White adipose tissue (WAT) produces interleukin-10 and other immune suppressors in response to pathogen-associated molecular patterns (PAMPs). It also homes a subset of B-cells specialized in the production of IL-10, referred to as regulatory B-cells
Externí odkaz:
https://doaj.org/article/4cd4bf1e46bd48b69a5db881632694f6
Autor:
Wilson Nguyen, Eri Nakayama, Kexin Yan, Bing Tang, Thuy T. Le, Liang Liu, Tamara H. Cooper, John D. Hayball, Helen M. Faddy, David Warrilow, Richard J. N. Allcock, Jody Hobson-Peters, Roy A. Hall, Daniel J. Rawle, Viviana P. Lutzky, Paul Young, Nidia M. Oliveira, Gunter Hartel, Paul M. Howley, Natalie A. Prow, Andreas Suhrbier
Publikováno v:
Vaccines, Vol 8, Iss 2, p 209 (2020)
Chikungunya virus (CHIKV), Ross River virus (RRV), o’nyong nyong virus (ONNV), Mayaro virus (MAYV) and Getah virus (GETV) represent arthritogenic alphaviruses belonging to the Semliki Forest virus antigenic complex. Antibodies raised against one of
Externí odkaz:
https://doaj.org/article/ab91253b909a4655ac9a7f198f2a6b40
Autor:
Lixin Wang, Yunmei Song, Ankit Parikh, Paul Joyce, Rosa Chung, Liang Liu, Franklin Afinjuomo, John D. Hayball, Nikolai Petrovsky, Thomas G. Barclay, Sanjay Garg
Publikováno v:
Pharmaceutics, Vol 11, Iss 11, p 581 (2019)
Delta inulin, also known as microparticulate inulin (MPI), was modified by covalently attaching doxorubicin to its nanostructured surface for use as a targeted drug delivery vehicle. MPI is readily endocytosed by monocytes, macrophages, and dendritic
Externí odkaz:
https://doaj.org/article/39f8058e82ff4064a2882746ce806d26