Zobrazeno 1 - 10
of 13
pro vyhledávání: '"John D. Broome"'
Publikováno v:
British Journal of Haematology. 106:477-485
In a unique case of chronic lymphocytic leukaemia (CLL) we performed a longitudinal cytogenetic and molecular genetic study of tumour cells from diagnosis through progression and transformation to non-Hodgkin's lymphoma (NHL) and lymphomatous meningi
Publikováno v:
Cancer Investigation. 11:25-32
N- and K-ras mutations at codons 12 and 13 were investigated using oligonucleotide hybridization analysis after PCR amplification and subsequent sequence analysis of the amplified DNA from the region of interest in the following prostatic primary and
Autor:
John D. Broome, Shiril M. Hombal, Philip Schulman, Prasad Koduru, William Muuse, Jonathan E. Kolitz, Myron Susin, Tsieh Sun, Saul Teichberg, Judith Brody
Publikováno v:
American Journal of Hematology. 40:135-145
Two cases of lymphoma of large granular lymphocytes are reported. The first case expressed natural killer (NK) cell, some T-cell (CD 2, CD 5, CD 8), and HLA-DR antigens, but was negative for other T-cell (CD 3, CD 4, CD 7), T-cell receptor (TCR), B-c
Autor:
L. Qian, J. P. Issa, L. O. Goodwin, John D. Broome, H. Peng, N. Shen, Prasad Koduru, Xinlai Sun
Publikováno v:
British Journal of Cancer
We have sequenced the promoter region of the murine asparagine synthetase gene and examined its methylation profile in the CpG islands of L-asparaginase-sensitive 6C3HED cells (asparagine auxotrophs) and resistant variants (prototrophs). In the forme
Publikováno v:
Experimental Biology and Medicine. 157:517-521
SummaryThe growth of thiol dependent cells of Lymphoma L1210(V) is supported by 3T3 and L cells as well as by macrophages in vitro. The supporting cells do not permanently condition the medium, but diffusion chamber studies show that growth promotion
Publikováno v:
Proceedings of the National Academy of Sciences. 69:1883-1886
Dopamine-β-hydroxylase activity is present in mouse neuroblastoma C-1300 tumors. The activity is proportional to the weight of the tumor. Serum activity is markedly increased in mice that bear the tumors. Treatment of mice with 5-bromodeoxyuridine c
Autor:
Eugene L. Opie, John D. Broome
Publikováno v:
The Journal of Experimental Medicine
When liver slices immediately after their removal from the body are immersed in graded solutions of sodium chloride, movement of water does not follow a course determined by movement of sodium ions. From hypotonic solutions sodium enters slowly and s
Publikováno v:
Proceedings of the National Academy of Sciences. 56:1516-1519
aginase with the lower affinity was ineffective. Agouti serum, which contains an L-asparaginase with an affinity intermediate between those of the two enzymes from E. coli, inhibited tumors less than did the E. coli enzyme with the higher affinity. W
Autor:
Patrick C. Chen, John D. Broome
Publikováno v:
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). 163(3)
SummaryMouse peritoneal macrophages in culture released a macromolecular factor capable of inhibiting mouse L1210 lymphoma cells in vitro. The factor was proved to be arginase by several criteria. The inhibition was reversed by adding arginine or cit
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 75(4)
Five different kinds of mouse lymphoma cells conditioned culture medium so that it became inhibitory to thiol-dependent cells but not to thiol-independent cells. Conditioning was rapid and appeared to be complete in 1-3 hr. The inhibitory effects cou