Zobrazeno 1 - 10
of 522
pro vyhledávání: '"John D. Baird"'
Autor:
Lan Gao, Diksha Kaushik, Brian A. Van Tine, Matthew A. Ingham, Steven Attia, Christian F. Meyer, Gary K. Schwartz, Pius Maliakal, John D. Baird, Jiyuan Ma, Rosemary Barrett, Dhiren D'Silva, Kylie O'Keefe, Ronald Kong
Publikováno v:
Clinical and Translational Science, Vol 17, Iss 2, Pp n/a-n/a (2024)
Abstract Unesbulin is being investigated in combination with dacarbazine (DTIC) as a potential therapeutic agent in patients with advanced leiomyosarcoma (LMS). This paper reports the pharmacokinetics (PK) of unesbulin, DTIC, and its unreactive surro
Externí odkaz:
https://doaj.org/article/67669181c17b40ddb322ddfc3dd1c1a1
Autor:
Anindya Dey, Shailendra Kumar Dhar Dwivedi, Lin Wang, Md Nazir Hossen, Fiifi Neizer-Ashun, Magdalena Bieniasz, Priyabrata Mukherjee, John D. Baird, Marla Weetall, Resham Bhattacharya
Publikováno v:
Genes and Diseases, Vol 9, Iss 6, Pp 1415-1418 (2022)
Externí odkaz:
https://doaj.org/article/a48c82a17d734bd19377dd0f2526ad7d
Publikováno v:
Genes, Vol 14, Iss 7, p 1479 (2023)
Spastic syndrome is a chronic, progressive disorder of adult cattle characterized by episodes of sudden involuntary muscle contractions or spasms of the extensor and abductor muscles of one or both hind limbs. In this study, a case-control genome-wid
Externí odkaz:
https://doaj.org/article/2f4833592ce04183a5b420cd1ecb8194
Autor:
Arthur Branstrom, Liangxian Cao, Bansri Furia, Christopher Trotta, Marianne Santaguida, Jason D. Graci, Joseph M. Colacino, Balmiki Ray, Wencheng Li, Josephine Sheedy, Anna Mollin, Shirley Yeh, Ronald Kong, Richard Sheridan, John D. Baird, Kylie O’Keefe, Robert Spiegel, Elizabeth Goodwin, Suzanne Keating, Marla Weetall
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Blocking the pyrimidine nucleotide de novo synthesis pathway by inhibiting dihydroorotate dehydrogenase (DHODH) results in the cell cycle arrest and/or differentiation of rapidly proliferating cells including activated lymphocytes, cancer cells, or v
Externí odkaz:
https://doaj.org/article/811abbf56e4c48f29740cec2bf4b6b7f
Autor:
Omid Teymournejad, Mingqun Lin, Hannah Bekebrede, Ahmed Kamr, Ramiro E. Toribio, Luis G. Arroyo, John D. Baird, Yasuko Rikihisa
Publikováno v:
mBio, Vol 11, Iss 2 (2020)
Externí odkaz:
https://doaj.org/article/f04317b668074d95b103ad391803d825
Autor:
Omid Teymournejad, Mingqun Lin, Hannah Bekebrede, Ahmed Kamr, Ramiro E. Toribio, Luis G. Arroyo, John D. Baird, Yasuko Rikihisa
Publikováno v:
mBio, Vol 11, Iss 1 (2020)
ABSTRACT Potomac horse fever (PHF), a severe and frequently fatal febrile diarrheal disease, has been known to be caused only by Neorickettsia risticii, an endosymbiont of digenean trematodes. Here, we report the cell culture isolation of a new Neori
Externí odkaz:
https://doaj.org/article/b0bfb3ef1f8f4e019ad4530da5336d9d
Publikováno v:
Case Reports in Veterinary Medicine, Vol 2014 (2014)
Auricular chondritis is an extremely rare condition in cattle and other domestic animals. A 13-month-old Jersey heifer was presented with cutaneous papillomatosis and bilaterally droopy ears. Histopathology revealed bilateral auricular chondritis cha
Externí odkaz:
https://doaj.org/article/d2585c4bd94e473bbebff0d4d52b0dbd
Autor:
Nicole Risher, Josephine Sheedy, Hasane Ratni, Zhihua Feng, Xin Zhao, Amal Dakka, Anna Mollin, Catherine Lutz, Karen K. Y. Ling, Ellen Welch, Friedrich Metzger, Marla Weetall, Karen S. Chen, Jana Narasimhan, Nikolai Naryshkin, John D. Baird, Chien-Ping Ko
Publikováno v:
Human Molecular Genetics. 31:82-96
Spinal muscular atrophy (SMA) is caused by the loss of the survival motor neuron 1 (SMN1) gene function. The related SMN2 gene partially compensates but produces insufficient levels of SMN protein due to alternative splicing of exon 7. Evrysdi™ (ri
Autor:
Khemraj Budachetri, Mingqun Lin, Qi Yan, Rory C. Chien, Laura D. Hostnik, Gillian Haanen, Mathilde Leclère, Warren Waybright, John D. Baird, Luis G. Arroyo, Yasuko Rikihisa
Publikováno v:
Journal of Clinical Microbiology. 60
Potomac horse fever (PHF) is an acute and potentially fatal enterotyphlocolitis of horses with clinical signs that include anorexia, fever, diarrhea, and laminitis. Its incidence is increasing despite a commercially available vaccine.
Autor:
Arthur Branstrom, Liangxian Cao, Bansri Furia, Christopher Trotta, Marianne Santaguida, Jason D. Graci, Joseph M. Colacino, Balmiki Ray, Wencheng Li, Josephine Sheedy, Anna Mollin, Shirley Yeh, Ronald Kong, Richard Sheridan, John D. Baird, Kylie O’Keefe, Robert Spiegel, Elizabeth Goodwin, Suzanne Keating, Marla Weetall
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Blocking the pyrimidine nucleotide de novo synthesis pathway by inhibiting dihydroorotate dehydrogenase (DHODH) results in the cell cycle arrest and/or differentiation of rapidly proliferating cells including activated lymphocytes, cancer cells, or v