Zobrazeno 1 - 10
of 396
pro vyhledávání: '"John D West"'
Autor:
John D West, Clare A Everett
Publikováno v:
Reproduction and Fertility, Vol 3, Iss 2, Pp R66-R90 (2022)
Some human preimplantation embryos are chromosomally mosaic. For technical reasons, estimates of the overall frequency vary widely from 90% and the true frequency remains unknown. Aneuploid/diploid and aneuploid/ aneuploid mosaics typically arise dur
Externí odkaz:
https://doaj.org/article/1fcb0f16263e4299a007eda48c3f9a54
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e109193 (2014)
Eye phenotypes were investigated in Le-Cre(Tg/-); Pax6(fl/+) mice, which were expected to show tissue-specific reduction of Pax6 in surface ectoderm derivatives. To provide a better comparison with our previous studies of Pax6(+/-) eye phenotypes, he
Externí odkaz:
https://doaj.org/article/631a27764f4d4615b0db9a0cf08fd051
Autor:
Kelly N H Nudelman, Yang Wang, Brenna C McDonald, Susan K Conroy, Dori J Smith, John D West, Darren P O'Neill, Bryan P Schneider, Andrew J Saykin
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e96713 (2014)
Cerebral structural and functional alterations have been reported after chemotherapy for non-CNS cancers, yet the causative mechanism behind these changes remains unclear. This study employed a novel, non-invasive, MRI-based neuroimaging measure to p
Externí odkaz:
https://doaj.org/article/ae25152a00ba4166b4cdb9ed6779e69e
Autor:
Shannon L Risacher, Yang eWang, Heather A Wishart, Laura A Rabin, Laura A Flashman, Brenna C McDonald, John D West, Robert B Santulli, Andrew J Saykin
Publikováno v:
Frontiers in Psychiatry, Vol 4 (2013)
Objective: To determine the physiological impact of treatment with donepezil (Aricept) on neural circuitry supporting episodic memory encoding in patients with amnestic mild cognitive impairment (MCI) using functional MRI (fMRI). Methods: 18 patients
Externí odkaz:
https://doaj.org/article/0e68003d2c1b4e8cae385a2dd230cb92
Autor:
Su-Ping Chang, Hamish D Morrison, Frida Nilsson, Christopher J Kenyon, John D West, Steven D Morley
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e81865 (2013)
Appropriate maintenance and regeneration of adult endocrine organs is important in both normal physiology and disease. We investigated cell proliferation, movement and differentiation in the adult mouse adrenal cortex, using different 5-bromo-2'-deox
Externí odkaz:
https://doaj.org/article/a2b281f35c054c4b9d9f5d07019e4e9e
Autor:
Panagiotis Douvaras, Richard L Mort, Dominic Edwards, Kanna Ramaesh, Baljean Dhillon, Steven D Morley, Robert E Hill, John D West
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e71117 (2013)
We aimed to test previous predictions that limbal epithelial stem cells (LESCs) are quantitatively deficient or qualitatively defective in Pax6(+/-) mice and decline with age in wild-type (WT) mice. Consistent with previous studies, corneal epithelia
Externí odkaz:
https://doaj.org/article/c3e3255cbdd045b4923635016e205e80
Autor:
Richard L Mort, Adam J Bentley, Francis L Martin, J Martin Collinson, Panagiotis Douvaras, Robert E Hill, Steven D Morley, Nigel J Fullwood, John D West
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e28895 (2011)
Altered dosage of the transcription factor PAX6 causes multiple human eye pathophysiologies. PAX6⁺/⁻ heterozygotes suffer from aniridia and aniridia-related keratopathy (ARK), a corneal deterioration that probably involves a limbal epithelial ste
Externí odkaz:
https://doaj.org/article/76f729e253d1417eadba95424dc96e78
Autor:
Shannon L. Risacher, John D. West, Rachael Deardorff, Sujuan Gao, Martin R. Farlow, Jared R. Brosch, Liana G. Apostolova, Thomas W. McAllister, Yu‐Chien Wu, William J. Jagust, Susan M. Landau, Michael W. Weiner, Andrew J. Saykin, for the Alzheimer's Disease Neuroimaging Initiative#
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 13, Iss 1, Pp n/a-n/a (2021)
Abstract Introduction Head injuries (HI) are a risk factor for dementia, but the underlying etiology is not fully known. Understanding whether tau might mediate this relationship is important. Methods Cognition and tau deposition were compared betwee
Externí odkaz:
https://doaj.org/article/54cf32b657e24c65976b025d4a854354
Autor:
Joey A. Contreras, Andrea Avena-Koenigsberger, Shannon L. Risacher, John D. West, Eileen Tallman, Brenna C. McDonald, Martin R. Farlow, Liana G. Apostolova, Joaquín Goñi, Mario Dzemidzic, Yu-Chien Wu, Daniel Kessler, Lucas Jeub, Santo Fortunato, Andrew J. Saykin, Olaf Sporns
Publikováno v:
NeuroImage: Clinical, Vol 22, Iss , Pp - (2019)
Alzheimer's disease is considered a disconnection syndrome, motivating the use of brain network measures to detect changes in whole-brain resting state functional connectivity (FC). We investigated changes in FC within and among resting state network
Externí odkaz:
https://doaj.org/article/344e3795dbed4b25886c116e42330129
Autor:
Tugce Duran, Ellen Woo, Diana Otero, Shannon L. Risacher, Eddie Stage, Apoorva B. Sanjay, Kwangsik Nho, John D. West, Meredith L. Phillips, Naira Goukasian, Kristy S. Hwang, Liana G. Apostolova
Publikováno v:
Brain Imaging Behav
Metacognitive deficits affect Alzheimer’s disease (AD) patient safety and increase caregiver burden. The brain areas that support metacognition are not well understood. 112 participants from the Imaging and Genetic Biomarkers for AD (ImaGene) study