Cis and trans determinants of epigenetic silencing by Polycomb repressive complex 2 in Arabidopsis

Autor: Run Jin, Alexandre M Santos, John D. Wagner, Sujuan Cui, Meilin Fernandez Garcia, Ryan S. Austin, Armaan Pai, Michael Zhuang, Roberto Bonasio, Xiaoyu Zhang, Samantha Klasfeld, Xiaowei Lin, Jun Xiao, Xiang Yu, Doris Wagner, Chongsheng He, Jose L. Pruneda-Paz, Max W. Shen, Justin Goodrich, Oliver Clarenz, Claire Song, Chris A. Helliwell, Steve A. Kay

Publikováno v: Xiao, J, Jin, R, Yu, X, Shen, M, Wagner, J, Pai, A, Song, C, Zhuang, M, Klasfeld, S, He, C, Santos, A M, Helliwell, C, Pruneda-Paz, J L, Kay, S A, Lin, X, Cui, S, Garcia, M F, Clarenz, O, Goodrich, W, Zhang, X, Austin, R S, Bonasio, R & Wagner, D 2017, ' Cis and trans determinants of epigenetic silencing by polycomb repressive complex 2 in Arabidopsis ', Nature Genetics, vol. 49, pp. 1546-1552 . https://doi.org/10.1038/ng.3937

Disruption of gene silencing by Polycomb protein complexes leads to homeotic transformations and altered developmental-phase identity in plants1–5. Here we define short genomic fragments, known as Polycomb response elements (PREs), that direct Poly

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b8612fcc3d484312df296079e6c8376
https://pubmed.ncbi.nlm.nih.gov/28825728

Grace for All : The Arminian Dynamics of Salvation

Autor: Clark H. Pinnock, John D. Wagner

Did Christ atone for the sins of humanity on the cross? Does God desire all people to be saved and direct his grace toward all people for that purpose? There are some Christians following a deterministic paradigm who believe this is not true. They be

Nitration of 1-dodecene with nitric acid

Autor: John D. Wagner, Rudolf J. Martens, Christopher E. Stubbs, Donald P. Gregory

Publikováno v: Journal of Applied Chemistry and Biotechnology. 26:623-630

A refluxing, heterogeneous mixture of l-dodecene with aqueous 30% nitric acid leads to a mixture of closely related nitroproducts in greater than 90 % yield within 3 h. Similarly various types of readily available olefins easily undergo nitration wit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a2f5ed72515924063c183617efdf3fe8
https://doi.org/10.1002/jctb.5020260187

H3K36 methylation promotes longevity by enhancing transcriptional fidelity

Autor: Kajia Cao, Greg Donahue, Chong He, Weiwei Dang, Daniel T. Carr, Jun Yeop Lee, Rocco Perry, Shelley L. Berger, Junbiao Dai, Brian M. Wasko, Matt Kaeberlein, Brian D. Gregory, Jef D. Boeke, Wei Liu, John D. Wagner, Brett Robison, Brian K. Kennedy, Jean Dorsey, Xiaohua Cao, Payel Sen

Publikováno v: Genesdevelopment. 29(13)

Epigenetic mechanisms, including histone post-translational modifications, control longevity in diverse organisms. Relatedly, loss of proper transcriptional regulation on a global scale is an emerging phenomenon of shortened life span, but the specif

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd437a60d61a941a49a1f3e4717c11ff
https://pubmed.ncbi.nlm.nih.gov/26159996

Lymphopenia in dialysis patients: a preliminary study indicating a possible role of apoptosis

Autor: Krishna Reddy, N Radhakrishnan, Nicholas Franki, R Ranjan, Robert B. Colvin, Pravin C. Singhal, John D. Wagner, Madhu Bhaskaran, Hitesh H. Shah, J Siu

Publikováno v: Clinical Nephrology. 57:221-229

Lymphopenia is a common finding in dialysis patients. Since infection rate and mortality associated with infection are high in dialysis patients, lymphopenia may be one of the contributing factors. In the present study, we evaluated the mechanism res

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe55db4fc549aa44bd267f0470dc30f5
https://doi.org/10.5414/cnp57221