Zobrazeno 1 - 10
of 102
pro vyhledávání: '"John D Olson"'
Publikováno v:
Research in Diagnostic and Interventional Imaging, Vol 5, Iss , Pp 100024- (2023)
Rationale and objectives: The accurate, non-invasive, and rapid measurement of renal cortical fibrosis is needed for well-defined benchmarks of permanent injury and for use of anti-fibrotic agents. It is also needed for non-invasive and rapid assessm
Externí odkaz:
https://doaj.org/article/12bdd5f479b14bd198dfd539e58883b6
Publikováno v:
PLoS ONE, Vol 15, Iss 2, p e0228626 (2020)
ObjectivesReliable biomarkers for renal fibrosis are needed for clinical care and for research. Existing non-invasive biomarkers are imprecise, which has limited their utility.MethodsWe developed a method to quantify fibrosis by subject size-adjusted
Externí odkaz:
https://doaj.org/article/fa49a6e0316b4a3b809a51ced1fc4049
Autor:
Shanaz A Ghandhi, Helen C Turner, Igor Shuryak, Gregory O Dugan, J Daniel Bourland, John D Olson, Janet A Tooze, Shad R Morton, Ines Batinic-Haberle, J Mark Cline, Sally A Amundson
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0191402 (2018)
We investigated the cytogenetic and gene expression responses of peripheral blood cells of non-human primates (NHP, Macaca mulatta) that were whole-thorax irradiated with a single dose of 10 Gy. In this model, partial irradiation of NHPs in the thora
Externí odkaz:
https://doaj.org/article/1e8da8efebcb4ad0be2450ba9f567b80
Autor:
Paulo A Garcia, John H Rossmeisl, John L Robertson, John D Olson, Annette J Johnson, Thomas L Ellis, Rafael V Davalos
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e50482 (2012)
The blood-brain-barrier (BBB) presents a significant obstacle to the delivery of systemically administered chemotherapeutics for the treatment of brain cancer. Irreversible electroporation (IRE) is an emerging technology that uses pulsed electric fie
Externí odkaz:
https://doaj.org/article/e0d4c0f247f6452fbef0800afebf1b6c
Autor:
Matthew J. French, Ryan Wuerker, Greg Dugan, John D. Olson, Brittany R. Sanders, Janet A. Tooze, David L. Caudell, J. Mark Cline, Gregory D. Sempowski, Andrew N. Macintyre
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 115:945-956
The aim of this study was to develop an improved understanding of the delayed immunologic effects of acute total body irradiation (TBI) using a diverse cohort of nonhuman primates as a model for an irradiated human population.Immune recovery was eval
Autor:
Mark P. Little, Alina V. Brenner, Eric J. Grant, Hiromi Sugiyama, Dale L. Preston, Ritsu Sakata, John Cologne, Raquel Velazquez-Kronen, Mai Utada, Kiyohiko Mabuchi, Kotaro Ozasa, John D. Olson, Gregory O. Dugan, Simonetta Pazzaglia, J. Mark Cline, Kimberly E. Applegate
Publikováno v:
International journal of radiation biology.
One of the principal uncertainties when estimating population risk of late effects from epidemiological data is that few radiation-exposed cohorts have been followed up to extinction. Therefore, the relative risk model has often been used to estimate
Publikováno v:
Radiation Research.
There is increasing evidence that circulatory disease incidence and mortality is associated with radiation exposure. Wake Forest School of Medicine is home to a unique cohort of total-body irradiated macaques, some with evidence of vascular end-organ
Autor:
Priyanka Thakur, John D. Olson, Gregory O Dugan, J. Daniel Bourland, Nancy D. Kock, J. Mark Cline
Publikováno v:
Radiation research.
Computed tomography (CT) imaging has been used to diagnose radiation-induced lung injury for decades. However, histogram-based quantitative tools have rarely been applied to assess lung abnormality due to radiation-induced lung injury (RILI). Here, w
Autor:
Oksana Volod, Andrew J. Goodwin, Dong Chen, Huy P. Pham, James Alexander Isom, Karen A. Moser, John D. Olson, Russell A. Higgins, Amanda M. VanSandt, Kristi J. Smock, Geoffrey D. Wool, Thomas A. Long, Marian A. Rollins-Raval, Neil S Harris, Wayne L. Chandler
Publikováno v:
Archives of Pathology & Laboratory Medicine. 146:145-153
Context.— Assessing direct oral anticoagulant (DOAC) drug levels by reliable laboratory assays is necessary in a number of clinical scenarios. Objective.— To evaluate the performance of DOAC-specific assays for various concentrations of dabigatra
Autor:
W. Shane Sills, Janet A. Tooze, John D. Olson, David L. Caudell, Greg O. Dugan, Brendan J. Johnson, Nancy D. Kock, Rachel N. Andrews, George W. Schaaf, Richard A. Lang, J. Mark Cline
Publikováno v:
Int J Radiat Oncol Biol Phys
PURPOSE: Cancer is a severe delayed effect of acute radiation exposure. Total-body irradiation has been associated with an increased risk of solid cancer and leukemia in Japanese atomic bomb survivors, and secondary malignancies, such as sarcoma, are