A multicentre observational study evaluating image-guided radiotherapy for more accurate partial-breast intensity-modulated radiotherapy: comparison with standard imaging technique

Autor: Emma J Harris, Mukesh Mukesh, Rajesh Jena, Angela Baker, Harry Bartelink, Corrinne Brooks, June Dean, Ellen M Donovan, Sandra Collette, Sally Eagle, John D Fenwick, Peter H Graham, Jo S Haviland, Anna M Kirby, Helen Mayles, Robert A Mitchell, Rosalind Perry, Philip Poortmans, Andrew Poynter, Glyn Shentall, Jenny Titley, Alistair Thompson, John R Yarnold, Charlotte E Coles, Philip M Evans, on behalf of the IMPORT Trials Management Group

Publikováno v: Efficacy and Mechanism Evaluation, Vol 1, Iss 3 (2014)

Background: Whole-breast radiotherapy (WBRT) is the standard treatment for breast cancer following breast-conserving surgery. Evidence shows that tumour recurrences occur near the original cancer: the tumour bed. New treatment developments include in

Externí odkaz: https://doaj.org/article/1dda8bc383744990b5ba37123bbe3057

Cardiac-sparing radiotherapy for locally advanced non-small cell lung cancer

Autor: Louise Turtle, Neeraj Bhalla, Andrew Willett, Robert Biggar, Jonathan Leadbetter, Georgios Georgiou, James M. Wilson, Sindu Vivekanandan, Maria A. Hawkins, Michael Brada, John D. Fenwick

Publikováno v: Radiation Oncology, Vol 16, Iss 1, Pp 1-10 (2021)

Abstract Background We have carried out a study to determine the scope for reducing heart doses in photon beam radiotherapy of locally advanced non-small cell lung cancer (LA-NSCLC). Materials and methods Baseline VMAT plans were created for 20 LA-NS

Externí odkaz: https://doaj.org/article/a1f5153fddc84f6c86ae64fdd12092de

Roadmap for Precision preclinical x-ray radiation studies

Autor: Frank Verhaegen, Karl T Butterworth, Anthony J Chalmers, Rob P Coppes, Dirk de Ruysscher, Sophie Dobiasch, John D Fenwick, Patrick V Granton, Stefan H J Heijmans, Mark A Hill, Constantinos Koumenis, Kirsten Lauber, Brian Marples, Katia Parodi, Lucas C G G Persoon, Nick Staut, Anna Subiel, Rianne D W Vaes, Stefan van Hoof, Ioannis L Verginadis, Jan J Wilkens, Kaye J Williams, George D Wilson, Ludwig J Dubois

Publikováno v: Physics in Medicine and Biology, 68(6). IOP Publishing Ltd.
Verhaegen, F, Butterworth, K T, Chalmers, A J, Coppes, R P, de Ruysscher, D, Dobiasch, S, Fenwick, J D, Granton, P V, Heijmans, S H J, Hill, M A, Koumenis, C, Lauber, K, Marples, B, Parodi, K, Persoon, L C G G, Staut, N, Subiel, A, Vaes, R D W, van Hoof, S, Verginadis, I L, Wilkens, J J, Williams, K J & Wilson, G D 2023, ' Roadmap for precision preclinical x-ray radiation studies ', Physics in Medicine and Biology, vol. 68, no. 6, 06RM01 . https://doi.org/10.1088/1361-6560/acaf45

This Roadmap paper covers the field of precision preclinical x-ray radiation studies in animal models. It is mostly focused on models for cancer and normal tissue response to radiation, but also discusses other disease models. The recent technologica

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05103f95458dc0a4608333fb04c34423
https://cris.maastrichtuniversity.nl/en/publications/ec5c3a0a-a978-4f52-b112-e310333f3236

Dose-Response Analysis Describes Particularly Rapid Repopulation of Non-Small Cell Lung Cancer during Concurrent Chemoradiotherapy

Autor: Huei-Tyng Huang, Michael G. Nix, Douglas H. Brand, David Cobben, Crispin T. Hiley, John D. Fenwick, Maria A. Hawkins

Publikováno v: Cancers; Volume 14; Issue 19; Pages: 4869

(1) Purpose: We analysed overall survival (OS) rates following radiotherapy (RT) and chemo-RT of locally-advanced non-small cell lung cancer (LA-NSCLC) to investigate whether tumour repopulation varies with treatment-type, and to further characterise

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cee39865b6fa2dcdd8f346a821554699

Collection efficiencies of ionization chambers in pulsed radiation beams: an exact solution of an ion recombination model including free electron effects

Autor: John D Fenwick, Sudhir Kumar

Publikováno v: Physics in medicine and biology. 68(1)

Objective. Boag et al (1996) formulated a key model of collection efficiency for ionization chambers in pulsed radiation beams, in which some free electrons form negatively charged ions with a density that initially varies exponentially across the ch

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3a410c656592fb4dafba3b6714b2747
https://pubmed.ncbi.nlm.nih.gov/36571457