Zobrazeno 1 - 10
of 338
pro vyhledávání: '"John D Aplin"'
Publikováno v:
Reproduction and Fertility, Vol 4, Iss 3, Pp 1-13 (2023)
Genome-wide analysis of gene expression has been widely applied to study the endometrium, although to our knowledge no systematic reviews have been performed. Here, we identified 74 studies that described transcriptomes from whole (unprocessed) endom
Externí odkaz:
https://doaj.org/article/21b461f7e77b49ca8a9ea3bbafac4ab2
Autor:
Stéphane C Berneau, Peter T Ruane, Daniel R Brison, Susan J Kimber, Melissa Westwood, John D Aplin
Publikováno v:
Cells, Vol 8, Iss 5, p 432 (2019)
At the onset of pregnancy, embryo implantation is initiated by interactions between the endometrial epithelium and the outer trophectoderm cells of the blastocyst. Osteopontin (OPN) is expressed in the endometrium and is implicated in attachment and
Externí odkaz:
https://doaj.org/article/089f6d7b97634a63b4785fc7e9939468
Autor:
Sylvia Lui, Rebecca L Jones, Nathalie J Robinson, Susan L Greenwood, John D Aplin, Clare L Tower
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e87328 (2014)
Fetal alcohol spectrum disorder (FASD) describes developmental issues from high maternal alcohol intake, which commonly results in fetal growth restriction and long term morbidity. We aimed to investigate the effect of alcohol and acetaldehyde, on th
Externí odkaz:
https://doaj.org/article/de99283e9bfc4d2b88c849cf869b9cc9
Autor:
Daniel K Shanley, Patrick A Kiely, Kalyan Golla, Seamus Allen, Kenneth Martin, Ronan T O'Riordan, Melanie Ball, John D Aplin, Bernhard B Singer, Noel Caplice, Niamh Moran, Tom Moore
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e57491 (2013)
Pregnancy-specific glycoproteins (PSGs) are immunoglobulin superfamily members encoded by multigene families in rodents and primates. In human pregnancy, PSGs are secreted by the syncytiotrophoblast, a fetal tissue, and reach a concentration of up to
Externí odkaz:
https://doaj.org/article/36cc399900a842d09f227e777a1b78db
Autor:
Alexandra J Umbers, Danielle I Stanisic, Maria Ome, Regina Wangnapi, Sarah Hanieh, Holger W Unger, Leanne J Robinson, Elvin Lufele, Francesca Baiwog, Peter M Siba, Christopher L King, James G Beeson, Ivo Mueller, John D Aplin, Jocelyn D Glazier, Stephen J Rogerson
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e55269 (2013)
BACKGROUND:Malaria in early pregnancy is difficult to study but has recently been associated with fetal growth restriction (FGR). The pathogenic mechanisms underlying malarial FGR are poorly characterized, but may include impaired placental developme
Externí odkaz:
https://doaj.org/article/cf097d66063e48d5840f42217f48966c
Autor:
Suzanne C Simmons, Edward A McKenzie, Lynda K Harris, John D Aplin, Paul E Brenchley, Maria N Velasco-Garcia, Sotiris Missailidis
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e37938 (2012)
Heparanase is an enzyme involved in extracellular matrix remodelling and heparan sulphate proteoglycan catabolism. It is secreted by metastatic tumour cells, allowing them to penetrate the endothelial cell layer and basement membrane to invade target
Externí odkaz:
https://doaj.org/article/7f9b5571bbff4c6691259dfd3a2c62ae
Autor:
Ming-Yi Lee, Jian-Pei Huang, Yi-Yung Chen, John D Aplin, Yi-Hsin Wu, Chia-Yu Chen, Pei-Chun Chen, Chie-Pein Chen
Publikováno v:
PLoS ONE, Vol 4, Iss 10, p e6913 (2009)
Human placental multipotent mesenchymal stromal cells (hPMSCs) can be isolated from term placenta, but their angiogenic ability and the regulatory pathways involved are not known. hPMSCs were shown to express integrins alpha(v), alpha(4), alpha(5), b
Externí odkaz:
https://doaj.org/article/bd9171c7dba743618b10a8dbebf3624d
Publikováno v:
Jones, C J P, Wilsher, S, Russo, G & Aplin, J D 2023, ' Lectin histochemistry reveals two cytotrophoblast differentiation pathways during placental development in the feline (Felis catus) ', Placenta, vol. 134, pp. 30-38 . https://doi.org/10.1016/j.placenta.2023.02.011
Introduction: Placental glycosylation has been examined on eight feline placentae ranging from approximately 15 to 60 days post-conception as little is known about changes in glycan distribution in this species. Methods: Specimens were resin embedded
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7edef35703c13cce8706e544289fb80c
https://doi.org/10.1016/j.placenta.2023.02.011
https://doi.org/10.1016/j.placenta.2023.02.011
Publikováno v:
Reproductive Medicine
Volume 4
Issue 1
Pages: 40-56
Volume 4
Issue 1
Pages: 40-56
Background: Single cell transcriptomics offers an avenue for predicting, with improved accuracy, the gene networks that are involved in the establishment of the first direct cell–cell interactions between the blastocyst and the maternal luminal epi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3da5cb12431954be40fa08f1be23da40
https://doi.org/10.3390/reprodmed4010006
https://doi.org/10.3390/reprodmed4010006
Targeted Delivery of Epidermal Growth Factor to the Human Placenta to Treat Fetal Growth Restriction
Autor:
Lewis J. Renshall, Frances Beards, Angelos Evangelinos, Susan L. Greenwood, Paul Brownbill, Adam Stevens, Colin P. Sibley, John D. Aplin, Edward D. Johnstone, Tambet Teesalu, Lynda K. Harris
Publikováno v:
Pharmaceutics, Vol 13, Iss 11, p 1778 (2021)
Placental dysfunction is the underlying cause of pregnancy complications such as fetal growth restriction (FGR) and pre-eclampsia. No therapies are available to treat a poorly functioning placenta, primarily due to the risks of adverse side effects i
Externí odkaz:
https://doaj.org/article/31d09fe8761e42b3bf935d5bee54fcfc